BR0004537A - Sìntese de antibióticos cetólidos carbamatos - Google Patents

Sìntese de antibióticos cetólidos carbamatos

Info

Publication number
BR0004537A
BR0004537A BR0004537-3A BR0004537A BR0004537A BR 0004537 A BR0004537 A BR 0004537A BR 0004537 A BR0004537 A BR 0004537A BR 0004537 A BR0004537 A BR 0004537A
Authority
BR
Brazil
Prior art keywords
synthesis
antibiotics
ketolide antibiotics
carbamate ketolide
macrolide antibiotic
Prior art date
Application number
BR0004537-3A
Other languages
English (en)
Inventor
Takushi Kaneko
Robert William Mclaughlin
William Thomas Mcmillen
David Harold Brown Ripin
Brian Clement Vanderplas
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of BR0004537A publication Critical patent/BR0004537A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Patente de Invenção: <B>"SìNTESE DE ANTIBIóTICOS CETóLIDOS CARBAMATOS"<D>. A invenção diz respeito a um método de preparação de um antibiótico macrólido de fórmula em que R¹, R², R³, R^ 4^, R^ 5^ são definidos acima. Estes antibióticos são úteis como agentes antibacterianos e antiprotozoários em mamíferos, incluindo o homem, bem como em peixes e aves. A invenção também inclui novos compostos feitos para a preparação do antibiótico macrólido.
BR0004537-3A 1999-09-29 2000-09-29 Sìntese de antibióticos cetólidos carbamatos BR0004537A (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US15655499P 1999-09-29 1999-09-29

Publications (1)

Publication Number Publication Date
BR0004537A true BR0004537A (pt) 2001-04-17

Family

ID=22560054

Family Applications (1)

Application Number Title Priority Date Filing Date
BR0004537-3A BR0004537A (pt) 1999-09-29 2000-09-29 Sìntese de antibióticos cetólidos carbamatos

Country Status (18)

Country Link
EP (1) EP1088828A3 (pt)
JP (1) JP2001151792A (pt)
KR (1) KR20010050704A (pt)
CN (1) CN1289778A (pt)
AR (1) AR023273A1 (pt)
AU (1) AU6129300A (pt)
BR (1) BR0004537A (pt)
CA (1) CA2321336C (pt)
CZ (1) CZ20003567A3 (pt)
HU (1) HUP0003834A3 (pt)
ID (1) ID27331A (pt)
IL (1) IL138633A0 (pt)
IN (2) IN187119B (pt)
PL (1) PL342917A1 (pt)
RU (1) RU2188827C2 (pt)
TR (1) TR200002787A2 (pt)
YU (1) YU57900A (pt)
ZA (1) ZA200005139B (pt)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1482957A4 (en) 2002-02-15 2006-07-19 Merckle Gmbh ANTIBIOTIC CONJUGATES
US20050171342A1 (en) 2002-02-15 2005-08-04 Michael Burnet Conjugates of biologically active compounds, methods for their preparation and use, formulation and pharmaceutical applications thereof
EP1483579A4 (en) 2002-02-15 2006-07-12 Merckle Gmbh CONJUGATES OF BIOLOGICALLY ACTIVE COMPOUNDS, METHODS FOR THE PREPARATION AND USE OF CONJUGATES, FORMULATION AND PHARMACEUTICAL APPLICATIONS OBTAINED FROM SUCH CONJUGATES
CN102199180B (zh) * 2011-04-12 2014-07-09 连云港杰瑞药业有限公司 一种卡培他滨的制备方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
BR9810021A (pt) * 1997-06-11 2000-09-19 Pfizer Prod Inc Derivados 9-oxima-eritromicina
HN1998000159A (es) * 1997-10-29 1999-02-09 Monsanto Co Derivados de 9- amino - 3 ceto eritromicina
AP1060A (en) * 1998-01-02 2002-04-23 Pfizer Prod Inc Novel erythromycin derivatives.

Also Published As

Publication number Publication date
IN188930B (pt) 2002-11-23
EP1088828A3 (en) 2001-04-11
IN187119B (pt) 2002-02-09
CA2321336C (en) 2005-03-15
HU0003834D0 (en) 2000-09-28
AR023273A1 (es) 2002-09-04
RU2188827C2 (ru) 2002-09-10
HUP0003834A2 (hu) 2001-05-28
CN1289778A (zh) 2001-04-04
HUP0003834A3 (en) 2001-07-30
CA2321336A1 (en) 2001-03-29
ZA200005139B (en) 2002-03-26
ID27331A (id) 2001-03-29
PL342917A1 (en) 2001-04-09
IL138633A0 (en) 2001-10-31
AU6129300A (en) 2001-04-05
CZ20003567A3 (cs) 2002-01-16
KR20010050704A (ko) 2001-06-15
TR200002787A2 (tr) 2001-04-20
EP1088828A2 (en) 2001-04-04
YU57900A (sh) 2003-02-28
JP2001151792A (ja) 2001-06-05

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Legal Events

Date Code Title Description
B08F Application dismissed because of non-payment of annual fees [chapter 8.6 patent gazette]

Free format text: REFERENTE A 7A, 8A, 9A E 10A ANUIDADE(S).

B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 2069 DE 31/08/2010.