BG99074A - Recombinant human hiv neutralizing monoclonal antibodies for prophylaxy and treatment of hiv infection - Google Patents

Recombinant human hiv neutralizing monoclonal antibodies for prophylaxy and treatment of hiv infection

Info

Publication number
BG99074A
BG99074A BG99074A BG9907494A BG99074A BG 99074 A BG99074 A BG 99074A BG 99074 A BG99074 A BG 99074A BG 9907494 A BG9907494 A BG 9907494A BG 99074 A BG99074 A BG 99074A
Authority
BG
Bulgaria
Prior art keywords
treatment
recombinant human
prophylaxy
hiv
monoclonal antibodies
Prior art date
Application number
BG99074A
Other languages
Bulgarian (bg)
English (en)
Inventor
Emilio Emini
Anthony Conley
George Mark
L. Johnson
David Pfarr
Original Assignee
Merck & Co. Inc.
Medimmune,Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co. Inc., Medimmune,Inc. filed Critical Merck & Co. Inc.
Publication of BG99074A publication Critical patent/BG99074A/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/42—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum viral
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • C07K16/1036—Retroviridae, e.g. leukemia viruses
    • C07K16/1045—Lentiviridae, e.g. HIV, FIV, SIV
    • C07K16/1063—Lentiviridae, e.g. HIV, FIV, SIV env, e.g. gp41, gp110/120, gp160, V3, PND, CD4 binding site
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Microbiology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Oncology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • AIDS & HIV (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG99074A 1992-04-01 1994-09-28 Recombinant human hiv neutralizing monoclonal antibodies for prophylaxy and treatment of hiv infection BG99074A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US86170192A 1992-04-01 1992-04-01
PCT/US1993/002629 WO1993019785A1 (fr) 1992-04-01 1993-03-23 Anticorps monoclonaux humains recombines neutralisant le vih destines a prevenir et a traiter l'infection due au vih

Publications (1)

Publication Number Publication Date
BG99074A true BG99074A (en) 1995-11-30

Family

ID=25336532

Family Applications (1)

Application Number Title Priority Date Filing Date
BG99074A BG99074A (en) 1992-04-01 1994-09-28 Recombinant human hiv neutralizing monoclonal antibodies for prophylaxy and treatment of hiv infection

Country Status (19)

Country Link
EP (1) EP0577243A3 (fr)
JP (1) JPH06217791A (fr)
KR (1) KR950700761A (fr)
CN (1) CN1081716A (fr)
AU (2) AU3928593A (fr)
BG (1) BG99074A (fr)
CA (1) CA2093099A1 (fr)
CZ (1) CZ239694A3 (fr)
FI (1) FI944561A (fr)
HU (1) HUT70461A (fr)
IL (1) IL105145A0 (fr)
MX (1) MX9301858A (fr)
NO (1) NO943653L (fr)
NZ (1) NZ251582A (fr)
RU (1) RU94045907A (fr)
SK (1) SK116294A3 (fr)
WO (1) WO1993019785A1 (fr)
YU (1) YU22693A (fr)
ZA (1) ZA932308B (fr)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2220114T3 (es) * 1998-10-30 2004-12-01 Novozymes A/S Variantes de proteinas poco alergenicas.
US7560529B2 (en) 2001-04-24 2009-07-14 FDS Pharma Method for producing catalytic antibodies (variants), antigens for immunization and nucleotide sequence
RU2221873C2 (ru) * 2001-04-24 2004-01-20 Закрытое акционерное общество "АСГЛ-Фармацевтические Инновации" Способ получения каталитических антител (варианты), антигены для иммунизации и нуклеотидная последовательность
FR2844455B1 (fr) * 2002-09-13 2007-12-14 Lab Francais Du Fractionnement Traitement des pathologies echappant a la reponse immune par des anticorps optimises
PT1595959E (pt) 2003-02-20 2015-03-05 Chemo Sero Therapeut Res Inst Método para melhorar a eficácia de uma preparação de anticorpo monoclonal
WO2009029569A1 (fr) * 2007-08-24 2009-03-05 Novartis Vaccines And Diagnostics Inc. Protéines env du vih avec modifications dans la boucle v3
TWI480268B (zh) 2008-12-09 2015-04-11 Gilead Sciences Inc 類鐸受體的調節劑
US10421803B2 (en) 2014-01-31 2019-09-24 The Rockefeller University Broadly neutralizing glycan-dependent 8ANC195 antibody variants that bind to an epitope spanning both HIV-1 Env subunits
AU2015287773B2 (en) 2014-07-11 2018-03-29 Gilead Sciences, Inc. Modulators of toll-like receptors for the treatment of HIV
WO2016044182A1 (fr) 2014-09-16 2016-03-24 Gilead Sciences, Inc. Formes solides d'un modulateur de récepteurs de type toll
WO2021227138A1 (fr) * 2020-05-09 2021-11-18 江苏省疾病预防控制中心(江苏省公共卫生研究院) Anticorps monoclonal du nouveau coronavirus, ou partie de liaison à l'antigène de celui-ci

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988009181A2 (fr) * 1987-05-29 1988-12-01 Tanox Biosystems, Inc. Anticorps monoclonaux neutralisant le hiv-1
EP0311228A3 (fr) * 1987-10-09 1990-05-02 Repligen Corporation Polypeptides recombinants et leur utilisation, y compris un diagnostic pour le virus du SIDA
AU6036690A (en) * 1989-06-05 1991-01-07 Helen F. Carson Human monoclonal antibodies to hiv-1mn gp 120
EP0535154A4 (en) * 1990-06-15 1993-12-01 New York University Heterohybridomas producing human monoclonal antibodies to hiv-1
AU668134B2 (en) * 1992-01-29 1996-04-26 United States Of America, Represented By The Secretary, Department Of Health And Human Services, The AAMP-1, a protein with local homologies to HIV-1 ENV and NEF proteins

Also Published As

Publication number Publication date
MX9301858A (es) 1994-03-31
CA2093099A1 (fr) 1993-10-02
JPH06217791A (ja) 1994-08-09
NO943653D0 (no) 1994-09-30
AU3563093A (en) 1993-10-07
CZ239694A3 (en) 1995-07-12
NZ251582A (en) 1997-07-27
FI944561A0 (fi) 1994-09-30
HU9402824D0 (en) 1994-11-28
NO943653L (no) 1994-11-30
HUT70461A (en) 1995-10-30
FI944561A (fi) 1994-09-30
EP0577243A3 (fr) 1994-11-02
IL105145A0 (en) 1993-07-08
WO1993019785A1 (fr) 1993-10-14
RU94045907A (ru) 1996-11-10
CN1081716A (zh) 1994-02-09
AU658987B2 (en) 1995-05-04
EP0577243A2 (fr) 1994-01-05
SK116294A3 (en) 1996-11-06
AU3928593A (en) 1993-11-08
KR950700761A (ko) 1995-02-20
YU22693A (sh) 1997-01-08
ZA932308B (en) 1994-09-30

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