BG60015A3 - Method for the preparation of 3-methoxy-4-/1-methyl-5/-2-methyl-4, 4, 4-trifluobutylcarbamoyl/-3-il-methyl/-n-/2-methylphenylsuphonyl/be nzamide - Google Patents

Method for the preparation of 3-methoxy-4-/1-methyl-5/-2-methyl-4, 4, 4-trifluobutylcarbamoyl/-3-il-methyl/-n-/2-methylphenylsuphonyl/be nzamide

Info

Publication number
BG60015A3
BG60015A3 BG93426A BG9342690A BG60015A3 BG 60015 A3 BG60015 A3 BG 60015A3 BG 93426 A BG93426 A BG 93426A BG 9342690 A BG9342690 A BG 9342690A BG 60015 A3 BG60015 A3 BG 60015A3
Authority
BG
Bulgaria
Prior art keywords
methyl
trifluobutylcarbamoyl
methylphenylsuphonyl
nzamide
methoxy
Prior art date
Application number
BG93426A
Inventor
Robert T Jacobs
Original Assignee
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Plc filed Critical Ici Plc
Priority to BG95502/91A priority Critical patent/BG50606A3/en
Publication of BG60015A3 publication Critical patent/BG60015A3/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04Indoles; Hydrogenated indoles
    • C07D209/10Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/02Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
    • C07C211/15Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
BG93426A 1989-12-11 1990-12-10 Method for the preparation of 3-methoxy-4-/1-methyl-5/-2-methyl-4, 4, 4-trifluobutylcarbamoyl/-3-il-methyl/-n-/2-methylphenylsuphonyl/be nzamide BG60015A3 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
BG95502/91A BG50606A3 (en) 1989-12-11 1990-12-10 Method for the preparation of 3- methoxy- 4- /1- methyl- 5-/ 2- methyl- 4, 4, 4- trifluorobutylcarbamoil/indol- 3- il- methyl/n- /2- methylphenylsulfonyl/benzamide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB898927981A GB8927981D0 (en) 1989-12-11 1989-12-11 Carbamoyl derivative

Publications (1)

Publication Number Publication Date
BG60015A3 true BG60015A3 (en) 1993-06-15

Family

ID=10667774

Family Applications (2)

Application Number Title Priority Date Filing Date
BG93426A BG60015A3 (en) 1989-12-11 1990-12-10 Method for the preparation of 3-methoxy-4-/1-methyl-5/-2-methyl-4, 4, 4-trifluobutylcarbamoyl/-3-il-methyl/-n-/2-methylphenylsuphonyl/be nzamide
BG95502/91A BG50606A3 (en) 1989-12-11 1990-12-10 Method for the preparation of 3- methoxy- 4- /1- methyl- 5-/ 2- methyl- 4, 4, 4- trifluorobutylcarbamoil/indol- 3- il- methyl/n- /2- methylphenylsulfonyl/benzamide

Family Applications After (1)

Application Number Title Priority Date Filing Date
BG95502/91A BG50606A3 (en) 1989-12-11 1990-12-10 Method for the preparation of 3- methoxy- 4- /1- methyl- 5-/ 2- methyl- 4, 4, 4- trifluorobutylcarbamoil/indol- 3- il- methyl/n- /2- methylphenylsulfonyl/benzamide

Country Status (32)

Country Link
EP (1) EP0432984B1 (en)
JP (1) JPH0822849B2 (en)
KR (1) KR100192999B1 (en)
CN (1) CN1025786C (en)
AP (1) AP192A (en)
AT (1) ATE163641T1 (en)
AU (1) AU642182B2 (en)
BG (2) BG60015A3 (en)
CA (1) CA2031897C (en)
CZ (1) CZ614690A3 (en)
DE (1) DE69032083T2 (en)
DK (1) DK0432984T3 (en)
ES (1) ES2112832T3 (en)
FI (1) FI95029C (en)
GB (2) GB8927981D0 (en)
GR (1) GR3026279T3 (en)
HK (1) HK1003830A1 (en)
HR (1) HRP930326B1 (en)
HU (2) HU210441B (en)
IE (1) IE904448A1 (en)
IL (1) IL96621A (en)
MY (1) MY106363A (en)
NO (1) NO174198C (en)
PL (2) PL167449B1 (en)
PT (1) PT96154B (en)
RO (1) RO108562B1 (en)
RU (1) RU2002740C1 (en)
SI (1) SI9012330A (en)
SK (1) SK278528B6 (en)
TW (1) TW219329B (en)
YU (1) YU48218B (en)
ZA (1) ZA909898B (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59103389D1 (en) * 1990-05-04 1994-12-08 Ciba Geigy Ag Substituted indoles.
GB9020338D0 (en) * 1990-09-18 1990-10-31 Lilly Industries Ltd Pharmaceutical compounds
GB9026427D0 (en) * 1990-12-05 1991-01-23 Ici Plc Chemical process
GB9026425D0 (en) * 1990-12-05 1991-01-23 Ici Plc Process
GB9119001D0 (en) * 1991-09-05 1991-10-23 Ici Plc Pharmaceutical agents
GR1001368B (en) * 1992-10-08 1993-10-29 Ici Plc Pharmaceutical agents.
ES2050611B1 (en) * 1992-10-08 1994-12-16 Ici Plc A NEW PHYSICAL FORM OF A CARBAMOILINDOL DERIVATIVE WITH ANTAGONIST PROPERTIES OF LEUCOTRENE.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4524152A (en) * 1982-12-30 1985-06-18 Pennwalt Corporation 1-Cyano-3-(fluoroalkyl)guanidines for lowering blood pressure
GB8623429D0 (en) * 1985-10-17 1986-11-05 Ici America Inc Carboximide derivatives
US4837235A (en) * 1985-10-17 1989-06-06 Ici Americas Inc. Indole and indazole keto sulphones as leukotriene antagonists
MY103259A (en) * 1987-04-15 1993-05-29 Ici America Inc Aliphatic carboxamides
GB8906032D0 (en) * 1988-04-14 1989-04-26 Ici America Inc Hetera-aliphatic carboxamides
GB9026425D0 (en) * 1990-12-05 1991-01-23 Ici Plc Process

Also Published As

Publication number Publication date
DE69032083D1 (en) 1998-04-09
KR100192999B1 (en) 1999-06-15
ES2112832T3 (en) 1998-04-16
FI95029C (en) 1995-12-11
NO174198C (en) 1994-04-06
FI95029B (en) 1995-08-31
HRP930326A2 (en) 1996-06-30
YU48218B (en) 1997-08-22
PT96154B (en) 1998-05-29
MY106363A (en) 1995-05-30
HU210877A9 (en) 1995-09-28
RO108562B1 (en) 1994-06-30
HU908137D0 (en) 1991-06-28
HK1003830A1 (en) 1998-11-06
HU210441B (en) 1995-04-28
IL96621A0 (en) 1991-09-16
AP9000230A0 (en) 1991-01-31
CA2031897A1 (en) 1991-06-12
JPH0770061A (en) 1995-03-14
FI906084A (en) 1991-06-12
CZ282068B6 (en) 1997-05-14
NO905327D0 (en) 1990-12-10
GB8927981D0 (en) 1990-02-14
BG50606A3 (en) 1992-09-15
AU642182B2 (en) 1993-10-14
FI906084A0 (en) 1990-12-11
HUT56345A (en) 1991-08-28
YU233090A (en) 1993-05-28
NO174198B (en) 1993-12-20
AP192A (en) 1992-06-30
GB2238790B (en) 1993-06-30
GR3026279T3 (en) 1998-06-30
KR910011780A (en) 1991-08-07
HRP930326B1 (en) 1998-12-31
IL96621A (en) 1994-11-28
ATE163641T1 (en) 1998-03-15
PT96154A (en) 1991-09-30
NO905327L (en) 1991-06-12
DE69032083T2 (en) 1998-07-16
SK614690A3 (en) 1997-08-06
ZA909898B (en) 1991-08-28
AU6791790A (en) 1991-06-13
CA2031897C (en) 2001-12-18
IE904448A1 (en) 1991-06-19
PL288184A1 (en) 1992-04-21
JPH0822849B2 (en) 1996-03-06
PL167449B1 (en) 1995-09-30
TW219329B (en) 1994-01-21
EP0432984A3 (en) 1992-04-22
EP0432984A2 (en) 1991-06-19
SK278528B6 (en) 1997-08-06
SI9012330A (en) 1997-12-31
GB2238790A (en) 1991-06-12
CN1025786C (en) 1994-08-31
DK0432984T3 (en) 1998-11-30
EP0432984B1 (en) 1998-03-04
PL166516B1 (en) 1995-05-31
CN1053604A (en) 1991-08-07
GB9026797D0 (en) 1991-01-30
RU2002740C1 (en) 1993-11-15
CZ614690A3 (en) 1997-05-14

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