BG27368A3 - Method of obtaining of substituted pyridines - Google Patents

Method of obtaining of substituted pyridines

Info

Publication number
BG27368A3
BG27368A3 BG033887A BG3388776A BG27368A3 BG 27368 A3 BG27368 A3 BG 27368A3 BG 033887 A BG033887 A BG 033887A BG 3388776 A BG3388776 A BG 3388776A BG 27368 A3 BG27368 A3 BG 27368A3
Authority
BG
Bulgaria
Prior art keywords
obtaining
substituted pyridines
pyridines
substituted
Prior art date
Application number
BG033887A
Other languages
Bulgarian (bg)
English (en)
Inventor
Graham Durant
Charon Ganellin
George Sach
Original Assignee
Неизвестен
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Неизвестен filed Critical Неизвестен
Publication of BG27368A3 publication Critical patent/BG27368A3/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/65—One oxygen atom attached in position 3 or 5
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/68—One oxygen atom attached in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
BG033887A 1975-07-31 1976-07-30 Method of obtaining of substituted pyridines BG27368A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB31970/75A GB1564502A (en) 1975-07-31 1975-07-31 Guanidines thioureas and 1,1-diamino-2-nitroethylene derivatives

Publications (1)

Publication Number Publication Date
BG27368A3 true BG27368A3 (en) 1979-10-12

Family

ID=10331105

Family Applications (1)

Application Number Title Priority Date Filing Date
BG033887A BG27368A3 (en) 1975-07-31 1976-07-30 Method of obtaining of substituted pyridines

Country Status (31)

Country Link
US (4) US4083983A (fr)
JP (2) JPS5219671A (fr)
AR (1) AR213736A1 (fr)
AT (1) AT356132B (fr)
AU (1) AU502752B2 (fr)
BE (1) BE844504A (fr)
BG (1) BG27368A3 (fr)
CA (1) CA1068711A (fr)
CH (1) CH624938A5 (fr)
CS (1) CS189018B2 (fr)
DD (1) DD125204A5 (fr)
DE (1) DE2634433A1 (fr)
DK (1) DK316176A (fr)
ES (1) ES450310A1 (fr)
FI (1) FI762193A (fr)
FR (1) FR2319343A1 (fr)
GB (1) GB1564502A (fr)
GR (1) GR60810B (fr)
HU (1) HU173778B (fr)
IE (1) IE43508B1 (fr)
IL (1) IL50005A (fr)
LU (1) LU75507A1 (fr)
NL (1) NL7608496A (fr)
NO (1) NO762661L (fr)
PH (1) PH14555A (fr)
PL (1) PL103684B1 (fr)
PT (1) PT65348B (fr)
SE (1) SE7608477L (fr)
SU (1) SU692558A3 (fr)
ZA (1) ZA764082B (fr)
ZM (1) ZM9876A1 (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS4928863A (fr) * 1972-07-13 1974-03-14
JPS5078968U (fr) * 1973-11-20 1975-07-08
ZA774220B (en) * 1976-07-28 1978-06-28 Smith Kline French Lab Pharmacologically active compounds
US4165378A (en) 1977-04-20 1979-08-21 Ici Americas Inc. Guanidine derivatives of imidazoles and thiazoles
IE47044B1 (en) 1977-04-20 1983-12-14 Ici Ltd Guanidine derivatives
US4233302A (en) * 1977-12-23 1980-11-11 Glaxo Group Limited Amine derivatives and pharmaceutical compositions containing them
US4282363A (en) * 1978-11-24 1981-08-04 Bristol-Myers Company 1-Nitro-2-(2-alkynylamino)-2-[(2-pyridylmethylthio)-ethylamino]ethylene derivatives
US4250316A (en) * 1978-11-24 1981-02-10 Bristol-Myers Company Pyridyl guanidine anti-ulcer agents
NL8000869A (nl) * 1979-02-16 1980-08-19 Eisai Co Ltd Cyanoguanidine-derivaten en werkwijze voor de bereiding daarvan.
PT74865B (en) * 1981-05-27 1983-12-07 Smithkline Beckman Corp Process of preparing a 2-(pyridylbutylamino)-pyrimidone and of its pharmaceutically acceptable salts
SE8204879D0 (sv) * 1982-08-26 1982-08-26 Haessle Ab Novel chemical intermediates
DE3232462A1 (de) * 1982-09-01 1984-03-01 Bayer Ag, 5090 Leverkusen 2-nitro-1,1-ethendiamine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
JPH0828166B2 (ja) * 1985-01-16 1996-03-21 松下電器産業株式会社 サ−モスタツト
AU660132B2 (en) * 1992-12-21 1995-06-08 Bayer Aktiengesellschaft Substituted 4-phenyl-pyridones and 4-phenyl-2-alkoxypyridine
US5380734A (en) * 1993-04-15 1995-01-10 American Home Products Corporation N-cyanoamidine derivatives as anti-influenza agents
CA3104669A1 (fr) 2018-06-29 2020-01-02 410 Medical, Inc. Systemes, appareil et procedes de filtration d'air a partir d'une ligne de fluide
EP4196793A1 (fr) 2020-08-11 2023-06-21 Université de Strasbourg Bloqueurs de h2 ciblant des macrophages du foie pour la prévention et le traitement d'une maladie du foie et du cancer

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3968216A (en) * 1969-10-29 1976-07-06 Smith Kline & French Laboratories Limited Method of inhibiting histamine activity with guanidine compounds
US3908014A (en) * 1970-06-25 1975-09-23 Smith Kline French Lab Pharmaceutical compositions and methods of inhibiting histamine activity with thiourea derivatives
US3808336A (en) 1970-06-25 1974-04-30 Smithkline Corp Pharmaceutical compositions and methods of inhibiting histamine activity with thiourea derivatives
GB1338169A (en) * 1971-03-09 1973-11-21 Smith Kline French Lab Ureas thioureas and guanidines
US3905984A (en) * 1971-03-09 1975-09-16 Smith Kline French Lab Pyridyl substituted thioalkyl-and oxyalkyl-thioureas and ureas
GB1397436A (en) * 1972-09-05 1975-06-11 Smith Kline French Lab Heterocyclic n-cyanoguinidines
GB1421792A (en) * 1973-05-17 1976-01-21 Smith Kline French Lab Heterocyclic substituted-1, 1-diamino-ethylene derivatives methods for their preparation and compositions containing them
US4002759A (en) * 1973-05-17 1977-01-11 Smith Kline & French Laboratories Limited Pyridylbutylamino ethylene compounds
US4025527A (en) * 1973-07-13 1977-05-24 Smith Kline & French Laboratories Limited Certain thiazoles and oxazoles
GB1497260A (en) * 1974-06-28 1978-01-05 Smith Kline French Lab Guanidine derivatives

Also Published As

Publication number Publication date
NO762661L (fr) 1977-02-01
AU502752B2 (en) 1979-08-09
DE2634433A1 (de) 1977-02-03
JPS5219671A (en) 1977-02-15
PH14555A (en) 1981-09-24
AT356132B (de) 1980-04-10
SE7608477L (sv) 1977-02-01
US4426526A (en) 1984-01-17
PT65348B (en) 1978-01-06
GR60810B (en) 1978-08-30
US4215126A (en) 1980-07-29
PL103684B1 (pl) 1979-07-31
PT65348A (en) 1976-08-01
CH624938A5 (fr) 1981-08-31
ZA764082B (en) 1977-06-29
US4264608A (en) 1981-04-28
ZM9876A1 (en) 1977-09-21
IE43508B1 (en) 1981-03-11
NL7608496A (nl) 1977-02-02
AR213736A1 (es) 1979-03-15
LU75507A1 (fr) 1977-03-03
IL50005A (en) 1981-06-29
DD125204A5 (fr) 1977-04-06
FR2319343A1 (fr) 1977-02-25
DK316176A (da) 1977-02-01
HU173778B (hu) 1979-08-28
AU1645376A (en) 1978-02-02
JPS617423B2 (fr) 1986-03-06
IL50005A0 (en) 1976-09-30
CA1068711A (fr) 1979-12-25
FR2319343B1 (fr) 1978-11-17
CS189018B2 (en) 1979-03-30
GB1564502A (en) 1980-04-10
ATA552576A (de) 1979-09-15
BE844504A (fr) 1977-01-24
JPS60243069A (ja) 1985-12-03
ES450310A1 (es) 1977-12-01
FI762193A (fr) 1977-02-01
SU692558A3 (ru) 1979-10-15
IE43508L (en) 1977-01-31
US4083983A (en) 1978-04-11

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