BG21606A3 - Метод за получаване на производни на пиперазинилхиноксалини - Google Patents

Метод за получаване на производни на пиперазинилхиноксалини

Info

Publication number
BG21606A3
BG21606A3 BG027222A BG2722274A BG21606A3 BG 21606 A3 BG21606 A3 BG 21606A3 BG 027222 A BG027222 A BG 027222A BG 2722274 A BG2722274 A BG 2722274A BG 21606 A3 BG21606 A3 BG 21606A3
Authority
BG
Bulgaria
Prior art keywords
piperazinylquinoxaline
derivatives
preparing
preparing piperazinylquinoxaline
piperazinylquinoxaline derivatives
Prior art date
Application number
BG027222A
Other languages
Bulgarian (bg)
English (en)
Inventor
Edward Engelhardt
William Lumma
Walfred Saari
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of BG21606A3 publication Critical patent/BG21606A3/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
BG027222A 1973-07-13 1974-07-13 Метод за получаване на производни на пиперазинилхиноксалини BG21606A3 (bg)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37902273A 1973-07-13 1973-07-13
US46538174A 1974-04-29 1974-04-29

Publications (1)

Publication Number Publication Date
BG21606A3 true BG21606A3 (bg) 1976-07-20

Family

ID=27008442

Family Applications (1)

Application Number Title Priority Date Filing Date
BG027222A BG21606A3 (bg) 1973-07-13 1974-07-13 Метод за получаване на производни на пиперазинилхиноксалини

Country Status (18)

Country Link
JP (1) JPS5037791A (fi)
AU (1) AU7073174A (fi)
BG (1) BG21606A3 (fi)
CH (1) CH605919A5 (fi)
DD (1) DD112127A5 (fi)
DE (1) DE2433397A1 (fi)
DK (1) DK342674A (fi)
ES (1) ES428107A1 (fi)
FI (1) FI193974A (fi)
FR (1) FR2236499B1 (fi)
GB (1) GB1440722A (fi)
IE (1) IE39869B1 (fi)
IL (1) IL45158A0 (fi)
LU (1) LU70510A1 (fi)
NL (1) NL7408705A (fi)
NO (1) NO742351L (fi)
RO (1) RO63539A (fi)
SE (1) SE417316B (fi)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4091098A (en) * 1977-04-25 1978-05-23 Merck & Co., Inc. 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides
US4082845A (en) 1977-04-25 1978-04-04 Merck & Co., Inc. 3-(1-Piperazinyl)-pyrido[2,3-b]pyrazines
US4107309A (en) * 1977-05-23 1978-08-15 American Cyanamid Company Substituted imidazo[1,2-d]-as-triazines
US4091101A (en) * 1977-06-15 1978-05-23 Merck & Co., Inc. 6-(1-Piperazinyl)quinoxaline
EP0094498A3 (en) * 1982-05-06 1985-04-03 American Cyanamid Company Antiatherosclerotic 1-piperazine derivatives
ES2042395B1 (es) * 1992-02-27 1994-06-16 Promotora Catalana De Inversio Procedimiento para la obtencion de derivados de 2-ciano-3-piperacinilquinoxalinas.
FR2731221B1 (fr) * 1995-03-01 1997-05-30 Pf Medicament Nouveaux derives de l'ethyl-1 dihydro-1, 2 oxo-2 methylamino-3 quinoxaline, leur utilisation a titre de medicament et les compositions pharmaceutiques les comprenant
EP1025097B1 (en) * 1997-10-24 2005-04-27 Neurogen Corporation 1-(2-naphthyl) and 1-(2-azanaphthyl)-4-(1-phenylmethyl)piperazines being dopamine d 4? receptor subtype ligands
US6040448A (en) 1997-10-24 2000-03-21 Neurogen Corporation Certain 1-(2-naphthyl) and 1-(2-azanaphthyl)-4-(1-phenylmethyl) piperazines, dopamine receptor subtype specific ligands
WO2000012500A2 (en) * 1998-09-02 2000-03-09 Neurogen Corporation 2-aryl-4-(1-[4-heteroaryl]piperazin-1-yl) methylimidazoles: dopamine d4 receptor subtype ligands
US6465467B1 (en) 1999-05-21 2002-10-15 Biovitrum Ab Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases
WO2000076984A2 (en) * 1999-05-21 2000-12-21 Biovitrum Ab Novel compounds, their use and preparation
SE9901884D0 (sv) * 1999-05-21 1999-05-21 Pharmacia & Upjohn Ab Novel compounds their use and preparation
JP4707261B2 (ja) * 2001-05-15 2011-06-22 日本エンバイロケミカルズ株式会社 キノキサリン系化合物および工業用殺菌組成物
JP4460450B2 (ja) 2002-06-19 2010-05-12 ビオヴィトルム・アクチボラゲット(プブリクト) 新規化合物、その使用および製造法
NZ537629A (en) * 2002-07-19 2007-05-31 Biovitrum Ab Novel piperazinyl-pyrazinone derivatives for the treatment of 5-HT2A receptor-related disorders
SE0202287D0 (sv) * 2002-07-19 2002-07-19 Biovitrum Ab New compounds
US8013156B2 (en) 2003-03-19 2011-09-06 Exelixis, Inc. Tie-2 modulators and methods of use
WO2005033088A1 (en) * 2003-09-30 2005-04-14 Janssen Pharmaceutica N.V. Quinoxaline compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL260335A (fi) * 1960-01-22
CH450434A (de) * 1961-12-14 1968-01-31 Ciba Geigy Verfahren zur Herstellung von Diazinen
BE788451A (fr) * 1971-09-08 1973-03-06 Bayer Ag Nouvelles 2-amino-quinoxalines, leur procede de preparation et leur application comme insecticides, acaricides et fongicides
GB1457005A (en) * 1972-11-20 1976-12-01 Pfizer 2-substituted-3-aminoquinoxalines

Also Published As

Publication number Publication date
DK342674A (fi) 1975-03-03
NO742351L (fi) 1975-02-10
DD112127A5 (fi) 1975-03-20
LU70510A1 (fi) 1975-03-27
SE417316B (sv) 1981-03-09
JPS5037791A (fi) 1975-04-08
IE39869L (en) 1975-01-13
FR2236499A1 (fi) 1975-02-07
FR2236499B1 (fi) 1977-04-15
AU7073174A (en) 1976-01-08
NL7408705A (nl) 1975-01-15
IE39869B1 (en) 1979-01-17
FI193974A (fi) 1975-01-14
GB1440722A (en) 1976-06-23
DE2433397A1 (de) 1975-02-06
RO63539A (fr) 1978-07-15
IL45158A0 (en) 1974-11-29
CH605919A5 (fi) 1978-10-13
ES428107A1 (es) 1976-11-16
SE7408486L (sv) 1975-01-14

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