BG105859A - Тетрахидропиранови производни и тяхното използване като терапевтични вещества - Google Patents
Тетрахидропиранови производни и тяхното използване като терапевтични вещества Download PDFInfo
- Publication number
- BG105859A BG105859A BG105859A BG10585901A BG105859A BG 105859 A BG105859 A BG 105859A BG 105859 A BG105859 A BG 105859A BG 10585901 A BG10585901 A BG 10585901A BG 105859 A BG105859 A BG 105859A
- Authority
- BG
- Bulgaria
- Prior art keywords
- alkyl
- alkoxy
- formula
- phenyl
- hydrogen
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Pain & Pain Management (AREA)
- Psychiatry (AREA)
- Rheumatology (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicinal Preparation (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9906480.0A GB9906480D0 (en) | 1999-03-19 | 1999-03-19 | Therapeutic agents |
GBGB9924616.7A GB9924616D0 (en) | 1999-10-18 | 1999-10-18 | Therapeutic agents |
PCT/GB2000/000977 WO2000056728A1 (en) | 1999-03-19 | 2000-03-16 | Tetrahydropyran derivatives and their use as therapeutic agents |
Publications (1)
Publication Number | Publication Date |
---|---|
BG105859A true BG105859A (bg) | 2002-04-30 |
Family
ID=26315315
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BG105859A BG105859A (bg) | 1999-03-19 | 2001-08-30 | Тетрахидропиранови производни и тяхното използване като терапевтични вещества |
Country Status (23)
Country | Link |
---|---|
US (1) | US6458830B1 (xx) |
EP (1) | EP1165540B1 (xx) |
JP (1) | JP2002540107A (xx) |
KR (1) | KR20010113773A (xx) |
CN (1) | CN1344264A (xx) |
AT (1) | ATE247096T1 (xx) |
AU (2) | AU3304400A (xx) |
BG (1) | BG105859A (xx) |
BR (1) | BR0009127A (xx) |
CA (1) | CA2367985A1 (xx) |
CO (1) | CO5150225A1 (xx) |
CZ (1) | CZ20013377A3 (xx) |
DE (1) | DE60004504T2 (xx) |
EA (1) | EA200100902A1 (xx) |
EE (1) | EE200100491A (xx) |
ES (1) | ES2203434T3 (xx) |
HU (1) | HUP0200441A3 (xx) |
IL (1) | IL144236A0 (xx) |
NO (1) | NO20014529L (xx) |
PE (1) | PE20001556A1 (xx) |
PL (1) | PL350123A1 (xx) |
SK (1) | SK13322001A3 (xx) |
WO (2) | WO2000056727A1 (xx) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10001785A1 (de) * | 2000-01-18 | 2001-07-19 | Boehringer Ingelheim Pharma | NK¶1¶-Rezeptor-Antagonisten zur Behandlung des Restless Legs Syndroms |
GB0017256D0 (en) | 2000-07-13 | 2000-08-30 | Merck Sharp & Dohme | Therapeutic agents |
GB0020721D0 (en) | 2000-08-22 | 2000-10-11 | Merck Sharp & Dohme | Therapeutic agents |
PE20020444A1 (es) | 2000-09-22 | 2002-06-14 | Merck & Co Inc | Antagonistas de receptores de taquiquinina zwitterionica |
JP2004518671A (ja) | 2001-01-17 | 2004-06-24 | メルク シャープ エンド ドーム リミテッド | ニューロキニン受容体アンタゴニストとしてのテトラヒドロピラン誘導体 |
GB0121874D0 (en) * | 2001-09-10 | 2001-10-31 | Merck Sharp & Dohme | Therapeutic agents |
GB0217068D0 (en) * | 2002-07-23 | 2002-08-28 | Merck Sharp & Dohme | Therapeutic agents |
WO2004037843A2 (en) * | 2002-10-25 | 2004-05-06 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Steroid compounds comprising superoxide dismutase mimic groups and nitric oxide donor groups, and their use in the preparation of medicaments |
AU2003286389A1 (en) * | 2002-11-29 | 2004-06-23 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Ace-inhibitors having antioxidant and nitricoxid-donor activity |
EP1603901B1 (en) | 2003-03-07 | 2008-10-15 | MERCK SHARP & DOHME LTD. | Tetrahydropyran compounds as tachykinin antagonists |
AU2005281703B2 (en) | 2004-09-08 | 2011-11-17 | Takeda Gmbh | Novel 3-thia-10-aza-phenanthrene derivatives |
EP1819661B1 (en) * | 2004-11-30 | 2009-04-22 | Mallinckrodt, Inc. | Crystallization method for benzphetamine |
AU2006240789B2 (en) * | 2005-04-22 | 2010-03-04 | Daiichi Sankyo Company, Limited | Heterocyclic compound |
CN100395242C (zh) * | 2006-06-08 | 2008-06-18 | 华东理工大学 | 烷氧基萘和萘醌类吡喃碳糖苷化合物及其制备方法 |
DE102007010077B4 (de) * | 2007-02-28 | 2010-04-08 | RUHR-UNIVERSITäT BOCHUM | [1,3]-Dioxane zur Modulation von GABAa-Rezeptoren |
EP2729147B1 (en) | 2011-07-04 | 2017-09-06 | IRBM - Science Park S.p.A. | Nk-1 receptor antagonists for treating corneal neovascularisation |
EP2892509A4 (en) * | 2012-09-04 | 2016-05-18 | Lauren Sciences Llc | BOLAAMPHIPHILIC COMPOUNDS, COMPOSITIONS AND USES THEREOF |
CA2951259A1 (en) | 2014-06-06 | 2015-12-10 | Flexus Biosciences, Inc. | Immunoregulatory agents |
UY36390A (es) | 2014-11-05 | 2016-06-01 | Flexus Biosciences Inc | Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido), sus métodos de síntesis y composiciones farmacéuticas que los contienen |
UY36391A (es) | 2014-11-05 | 2016-06-01 | Flexus Biosciences Inc | Compuestos moduladores de la enzima indolamina 2,3-dioxigenasa (ido1), sus métodos de síntesis y composiciones farmacèuticas que las contienen |
EA201790806A1 (ru) | 2014-11-05 | 2017-11-30 | Флексус Байосайенсиз, Инк. | Иммунорегулирующие средства |
HU231150B1 (hu) | 2017-03-13 | 2021-03-29 | Richter Gedeon Nyrt | Eljárás racém 3-alkilpiperidin-3-karbonsav-etil-észterek optikai izomerjeinek elválasztására |
ES2963437T3 (es) * | 2018-02-06 | 2024-03-27 | Daiichi Sankyo Co Ltd | Compuesto de aminoalquilo |
US20210015834A1 (en) | 2018-02-26 | 2021-01-21 | Ospedale San Raffaele S.R.L. | Nk-1 antagonists for use in the treatment of ocular pain |
US20230134843A1 (en) | 2020-03-11 | 2023-05-04 | Ospedale San Raffaele S.R.L. | Treatment of stem cell deficiency |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9301920D0 (en) * | 1993-02-01 | 1993-03-17 | Foundation For Ethnobiology Th | Polycetylenes |
-
2000
- 2000-03-10 CO CO00017612A patent/CO5150225A1/es unknown
- 2000-03-13 PE PE2000000218A patent/PE20001556A1/es not_active Application Discontinuation
- 2000-03-16 SK SK1332-2001A patent/SK13322001A3/sk unknown
- 2000-03-16 EA EA200100902A patent/EA200100902A1/ru unknown
- 2000-03-16 WO PCT/GB2000/000974 patent/WO2000056727A1/en active IP Right Grant
- 2000-03-16 WO PCT/GB2000/000977 patent/WO2000056728A1/en not_active Application Discontinuation
- 2000-03-16 DE DE60004504T patent/DE60004504T2/de not_active Expired - Fee Related
- 2000-03-16 AT AT00911045T patent/ATE247096T1/de not_active IP Right Cessation
- 2000-03-16 KR KR1020017011885A patent/KR20010113773A/ko not_active Application Discontinuation
- 2000-03-16 AU AU33044/00A patent/AU3304400A/en not_active Abandoned
- 2000-03-16 ES ES00911045T patent/ES2203434T3/es not_active Expired - Lifetime
- 2000-03-16 CZ CZ20013377A patent/CZ20013377A3/cs unknown
- 2000-03-16 CA CA002367985A patent/CA2367985A1/en not_active Abandoned
- 2000-03-16 CN CN00805114A patent/CN1344264A/zh active Pending
- 2000-03-16 EE EEP200100491A patent/EE200100491A/xx unknown
- 2000-03-16 US US09/936,343 patent/US6458830B1/en not_active Expired - Fee Related
- 2000-03-16 PL PL00350123A patent/PL350123A1/xx not_active Application Discontinuation
- 2000-03-16 AU AU33042/00A patent/AU746251B2/en not_active Ceased
- 2000-03-16 IL IL14423600A patent/IL144236A0/xx unknown
- 2000-03-16 HU HU0200441A patent/HUP0200441A3/hu unknown
- 2000-03-16 JP JP2000606588A patent/JP2002540107A/ja not_active Withdrawn
- 2000-03-16 BR BR0009127-8A patent/BR0009127A/pt not_active Application Discontinuation
- 2000-03-16 EP EP00911045A patent/EP1165540B1/en not_active Expired - Lifetime
-
2001
- 2001-08-30 BG BG105859A patent/BG105859A/bg unknown
- 2001-09-18 NO NO20014529A patent/NO20014529L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EE200100491A (et) | 2002-12-16 |
BR0009127A (pt) | 2001-12-26 |
NO20014529D0 (no) | 2001-09-18 |
AU3304400A (en) | 2000-10-09 |
DE60004504D1 (de) | 2003-09-18 |
CA2367985A1 (en) | 2000-09-28 |
ATE247096T1 (de) | 2003-08-15 |
WO2000056728A1 (en) | 2000-09-28 |
SK13322001A3 (sk) | 2002-02-05 |
JP2002540107A (ja) | 2002-11-26 |
CN1344264A (zh) | 2002-04-10 |
PL350123A1 (en) | 2002-11-04 |
DE60004504T2 (de) | 2004-06-24 |
EP1165540A1 (en) | 2002-01-02 |
CZ20013377A3 (cs) | 2002-02-13 |
CO5150225A1 (es) | 2002-04-29 |
EP1165540B1 (en) | 2003-08-13 |
NO20014529L (no) | 2001-11-13 |
AU3304200A (en) | 2000-10-09 |
HUP0200441A2 (hu) | 2002-07-29 |
ES2203434T3 (es) | 2004-04-16 |
WO2000056727A1 (en) | 2000-09-28 |
IL144236A0 (en) | 2002-05-23 |
PE20001556A1 (es) | 2001-01-13 |
EA200100902A1 (ru) | 2002-02-28 |
AU746251B2 (en) | 2002-04-18 |
US6458830B1 (en) | 2002-10-01 |
KR20010113773A (ko) | 2001-12-28 |
HUP0200441A3 (en) | 2002-09-30 |
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