BG105458A - Dna molecules encoding muc-1 and use thereof in tumor vaccination - Google Patents

Dna molecules encoding muc-1 and use thereof in tumor vaccination

Info

Publication number
BG105458A
BG105458A BG105458A BG10545801A BG105458A BG 105458 A BG105458 A BG 105458A BG 105458 A BG105458 A BG 105458A BG 10545801 A BG10545801 A BG 10545801A BG 105458 A BG105458 A BG 105458A
Authority
BG
Bulgaria
Prior art keywords
dna molecules
molecules encoding
tumor vaccination
encoding muc
tumor
Prior art date
Application number
BG105458A
Other languages
Bulgarian (bg)
English (en)
Inventor
Dino Parente
MASSIMO Anna Maria DI
Santis Rita De
Original Assignee
Menarini Ricerche S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Menarini Ricerche S.P.A. filed Critical Menarini Ricerche S.P.A.
Publication of BG105458A publication Critical patent/BG105458A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4727Mucins, e.g. human intestinal mucin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/0011Cancer antigens
    • A61K39/001136Cytokines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
BG105458A 1998-10-30 2001-04-20 Dna molecules encoding muc-1 and use thereof in tumor vaccination BG105458A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT1998MI002330A IT1303683B1 (it) 1998-10-30 1998-10-30 Composizione farmaceutiche ad azione antitumorale contenente dnacodificante per frammenti di una proteina antigenica.
PCT/EP1999/007874 WO2000025827A2 (en) 1998-10-30 1999-10-18 Dna molecules encoding muc-1 and use thereof in tumor vaccination

Publications (1)

Publication Number Publication Date
BG105458A true BG105458A (en) 2002-06-28

Family

ID=11380969

Family Applications (1)

Application Number Title Priority Date Filing Date
BG105458A BG105458A (en) 1998-10-30 2001-04-20 Dna molecules encoding muc-1 and use thereof in tumor vaccination

Country Status (19)

Country Link
EP (1) EP1124956A2 (xx)
JP (1) JP2002528519A (xx)
CN (1) CN1324406A (xx)
AR (1) AR020927A1 (xx)
AU (1) AU1152200A (xx)
BG (1) BG105458A (xx)
BR (1) BR9914892A (xx)
CA (1) CA2348745A1 (xx)
CO (1) CO5231134A1 (xx)
CZ (1) CZ20011521A3 (xx)
EA (1) EA200100395A1 (xx)
HU (1) HUP0103784A2 (xx)
IT (1) IT1303683B1 (xx)
MX (1) MXPA01004186A (xx)
PE (1) PE20001287A1 (xx)
PL (1) PL348156A1 (xx)
SK (1) SK5712001A3 (xx)
TR (1) TR200101141T2 (xx)
WO (1) WO2000025827A2 (xx)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6548643B1 (en) 1994-11-16 2003-04-15 Austin Research Institute Antigen carbohydrate compounds and their use in immunotherapy
WO2001057068A1 (en) * 2000-02-01 2001-08-09 The Austin Research Institute Mucin-1 derived antigens and their use in immunotherapy
JP5165175B2 (ja) * 2000-09-11 2013-03-21 デイナ ファーバー キャンサー インスティチュート,インコーポレイテッド Muc1細胞外ドメインおよびそれから得られた癌治療組成物
JP4276432B2 (ja) 2000-12-22 2009-06-10 ダナ−ファーバー キャンサー インスティテュート,インコーポレイテッド Muc1による細胞増殖調節方法
PL1622648T3 (pl) * 2003-03-24 2010-11-30 Scripps Research Inst Szczepionki DNA przeciwko wzrostowi nowotworów i sposoby ich stosowania
US7696306B2 (en) 2003-07-11 2010-04-13 Board of Agents of the University of Nebraska Compositions and methods for preventing or treating cancer
WO2005042573A1 (en) * 2003-10-24 2005-05-12 Dana-Farber Cancer Institute, Inc. Modulation of the interaction of muc1 with muc1 ligands
US7871784B2 (en) 2007-02-02 2011-01-18 Dana-Farber Cancer Institute, Inc. Methods and compositions relating to the regulation of apoptosis by MUC1 and BH3-containing proapoptotic proteins
US7972870B2 (en) 2007-02-02 2011-07-05 Dana-Farber Cancer Institute, Inc. Methods and compositions relating to the regulation of MUC1 by HSF1 and STAT3
CN106279435B (zh) * 2016-08-16 2019-06-07 新乡医学院 靶向VEGF与mucin1的抗肿瘤疫苗、编码基因、表达载体、表达工程菌及应用
CN114230656A (zh) * 2021-03-24 2022-03-25 深圳市新靶向生物科技有限公司 一种与食道癌驱动基因突变相关的抗原肽组合及其应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1262545B (it) * 1993-10-25 1996-07-02 Menarini Ricerche Sud S P A A Sistema di espressione per linee cellulari eucariotiche
AU727308B2 (en) * 1997-02-24 2000-12-07 Dana-Farber Cancer Institute Recombinant pox virus for immunization against muc1 tumor-associated antigen

Also Published As

Publication number Publication date
BR9914892A (pt) 2001-07-17
CO5231134A1 (es) 2002-12-27
PL348156A1 (en) 2002-05-06
ITMI982330A0 (it) 1998-10-30
WO2000025827A3 (en) 2000-08-10
AU1152200A (en) 2000-05-22
HUP0103784A2 (hu) 2002-02-28
PE20001287A1 (es) 2000-12-07
TR200101141T2 (tr) 2001-09-21
EP1124956A2 (en) 2001-08-22
WO2000025827A2 (en) 2000-05-11
MXPA01004186A (es) 2002-06-04
ITMI982330A1 (it) 2000-04-30
CN1324406A (zh) 2001-11-28
CZ20011521A3 (cs) 2001-10-17
CA2348745A1 (en) 2000-05-11
EA200100395A1 (ru) 2001-10-22
AR020927A1 (es) 2002-06-05
JP2002528519A (ja) 2002-09-03
SK5712001A3 (en) 2002-04-04
IT1303683B1 (it) 2001-02-23

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