BG104801A - Indole-2,3-dione-3-oxime derivatives for therapeutical use - Google Patents

Indole-2,3-dione-3-oxime derivatives for therapeutical use

Info

Publication number
BG104801A
BG104801A BG104801A BG10480100A BG104801A BG 104801 A BG104801 A BG 104801A BG 104801 A BG104801 A BG 104801A BG 10480100 A BG10480100 A BG 10480100A BG 104801 A BG104801 A BG 104801A
Authority
BG
Bulgaria
Prior art keywords
dione
indole
oxime derivatives
therapeutical use
therapeutical
Prior art date
Application number
BG104801A
Other languages
Bulgarian (bg)
English (en)
Inventor
Frank Waetjen
Jorgen Drejer
Original Assignee
Neurosearch A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Neurosearch A/S filed Critical Neurosearch A/S
Publication of BG104801A publication Critical patent/BG104801A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurosurgery (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Addiction (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
BG104801A 1998-03-31 2000-09-27 Indole-2,3-dione-3-oxime derivatives for therapeutical use BG104801A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK45298 1998-03-31
DK46298 1998-04-01
PCT/DK1999/000194 WO1999049864A1 (en) 1998-03-31 1999-03-30 Indole-2,3-dione-3-oxime derivatives for therapeutic use

Publications (1)

Publication Number Publication Date
BG104801A true BG104801A (en) 2001-04-30

Family

ID=26064032

Family Applications (1)

Application Number Title Priority Date Filing Date
BG104801A BG104801A (en) 1998-03-31 2000-09-27 Indole-2,3-dione-3-oxime derivatives for therapeutical use

Country Status (10)

Country Link
US (1) US6239128B1 (ja)
EP (1) EP1066037B1 (ja)
JP (1) JP2002509885A (ja)
AT (1) ATE285772T1 (ja)
AU (1) AU751414B2 (ja)
BG (1) BG104801A (ja)
CA (1) CA2326576A1 (ja)
DE (1) DE69922936T2 (ja)
NZ (1) NZ507259A (ja)
WO (1) WO1999049864A1 (ja)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60041399D1 (de) * 1999-05-19 2009-03-05 Painceptor Pharma Corp Hemmer der protonenabhängigen kationenkanäle und deren verwendung in der behandlung von ischemiebedingten erkrankungen
ES2266214T3 (es) * 2000-01-24 2007-03-01 Neurosearch A/S Derivados de isatina con actividad neurotrofica.
MXPA04000358A (es) 2001-07-13 2004-05-04 Pharmacia & Up John Company Hexahidroazepino (4,5-g) indoles e indolinas como ligandos del receptor 5-ht.
WO2004018466A2 (en) * 2002-08-22 2004-03-04 Neurosearch A/S A method of preparing enantiomers of indole-2,3-dione-3-oxime derivatives
EP1957486A4 (en) * 2005-11-23 2009-11-11 Painceptor Pharma Corp COMPOSITIONS AND METHODS FOR MODULATION OF IONIC CHANNELS
WO2007115403A1 (en) * 2006-04-10 2007-10-18 Painceptor Pharma Corporation Compositions and methods for modulating gated ion channels
WO2007115409A1 (en) * 2006-04-10 2007-10-18 Painceptor Pharma Corporation Compositions and methods for modulating gated ion channels
US20100041691A1 (en) * 2006-09-12 2010-02-18 Neurosearch A/S Pharmaceutical compositions comprising combinations of an ampa/kainate antagonistic compound and an inhibitor of a multidrug resistance protein
CN102653538A (zh) * 2011-03-04 2012-09-05 爱斯医药科技(南京)有限公司 Spd-502的制备方法
CN104725372B (zh) * 2015-01-28 2017-02-22 天津科技大学 四环吲哚生物碱衍生物及其制备和应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994026747A1 (en) * 1993-05-13 1994-11-24 Neurosearch A/S Ampa antagonists and a method of treatment therewith
GB9418357D0 (en) * 1994-09-12 1994-11-02 Chiroscience Ltd Amidation process
AU687255B2 (en) * 1994-09-14 1998-02-19 Neurosearch A/S Indole-2,3-dione-3-oxime derivatives, their preparation and use
UA54403C2 (uk) * 1996-10-01 2003-03-17 Н'Юросерч А/С Похідні індол-2,3-діон-3-оксиму, фармацевтична композиція, спосіб лікування розладу чи захворювання ссавців, у тому числі людини та спосіб одержання похідних індол-2,3-діон-3-оксиму

Also Published As

Publication number Publication date
US6239128B1 (en) 2001-05-29
JP2002509885A (ja) 2002-04-02
DE69922936D1 (de) 2005-02-03
NZ507259A (en) 2003-07-25
WO1999049864A1 (en) 1999-10-07
AU751414B2 (en) 2002-08-15
EP1066037A1 (en) 2001-01-10
DE69922936T2 (de) 2005-12-08
ATE285772T1 (de) 2005-01-15
CA2326576A1 (en) 1999-10-07
AU2921999A (en) 1999-10-18
EP1066037B1 (en) 2004-12-29

Similar Documents

Publication Publication Date Title
ZA200501082B (en) Substituted 1,3-diphenylprop-2-en-1-one derivatives and preparation and uses thereof
MY115977A (en) Synthetic excitatory amino acids
TR200002773T2 (tr) Alzheimer tedavisi için smilagenin ve anzurogenin-D ve bunların kullanımı.
PT1446387E (pt) Derivados de aril-1,4-pirazina substituídos
MY130489A (en) Substituted aryl 1, 4-pyrazine derivatives
BG107016A (en) 2-oxo-1-pyrrolidine derivatives, process for preparing them and their uses
BG100974A (en) Vaccines against papillomavirus
AU2964295A (en) Inhibitors of leukocyte adhesion
BG104236A (en) Transgenous mammals producing oligosaccharides in their milk
BG102947A (en) Ionic conjugates with delayed release
ATE366099T1 (de) Vorrichtung zur physikalischen therapie der schulter
MX9704030A (es) 1,1-dioxidos de 2-heterocicliloxi y tiometil-1,2,5-tiadiazolidin-3-ona y composiciones y metodo de uso de los mismos.
AU1945795A (en) Thieno{ 2,3-b}indoles, their preparation and use
IL127918A0 (en) Novel amino sugar and related sugar derivatives of indolylopyrrolocarbazoles their use as antitumor agents and pharmaceutical formulations
IE902288L (en) Tetrazolylmethylpiperidine carboxylic acid
BG104801A (en) Indole-2,3-dione-3-oxime derivatives for therapeutical use
BG102623A (en) New derivatives of benzoylguanadine, methods for their preparation and application for the manufacture of medicamentous forms
AU3009089A (en) Tetrazole excitatory amino acid receptor antagonists
GR3034575T3 (en) Steroid nitrite ester derivatives useful as anti-inflammatory drugs
BG105275A (en) Tan-1057 derivatives
BG102814A (en) New derivatives of carboxylic acid, their preparation and application
TR200001102T2 (tr) İkameli tetrahidropirimidinen türevleri, üretimleri ve kullanımları.
MX9704034A (es) Derivados y composiciones de 1,1-dioxido de 2-arilcarboniloximetil-1,2,5-tiadiazolidin-3-ona substituido y metodo de uso.
CA2296560A1 (en) Amino acid derivatives useful to treat stroke
IL116843A (en) Glycine and sarcosine derivatives as intermediates and a process for their preparation