BE905601A - DICHLOROANILINE DERIVATIVES. - Google Patents
DICHLOROANILINE DERIVATIVES.Info
- Publication number
- BE905601A BE905601A BE0/217292A BE217292A BE905601A BE 905601 A BE905601 A BE 905601A BE 0/217292 A BE0/217292 A BE 0/217292A BE 217292 A BE217292 A BE 217292A BE 905601 A BE905601 A BE 905601A
- Authority
- BE
- Belgium
- Prior art keywords
- dichloroaniline derivatives
- dichloroaniline
- derivatives
- solvates
- asthma
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C211/00—Compounds containing amino groups bound to a carbon skeleton
- C07C211/43—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
- C07C211/44—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having amino groups bound to only one six-membered aromatic ring
- C07C211/45—Monoamines
- C07C211/46—Aniline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Composés de la formule générale, dans laquelle R1, R2, X, Y et Ar possèdent les significations définies, ainsi que leurs sels et solvates (notamment hydrates) physiologiquement acceptables, qui possèdent une action stimulante au niveau des récepteurs beta 2-adrénergiques et peuvent etre utilisés dans la traitement de maladie associées à l'obstruction réversible des voies respiratoires comme l'asthme et la bronchite chronique.Compounds of the general formula, in which R1, R2, X, Y and Ar have the defined meanings, as well as their physiologically acceptable salts and solvates (in particular hydrates), which have a stimulating action at the level of beta 2-adrenergic receptors and can be used in the treatment of diseases associated with reversible airway obstruction such as asthma and chronic bronchitis.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858525321A GB8525321D0 (en) | 1985-10-15 | 1985-10-15 | Chemical compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
BE905601A true BE905601A (en) | 1987-04-15 |
Family
ID=10586651
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE0/217292A BE905601A (en) | 1985-10-15 | 1986-10-15 | DICHLOROANILINE DERIVATIVES. |
Country Status (21)
Country | Link |
---|---|
JP (1) | JPS62149651A (en) |
KR (1) | KR870003970A (en) |
AT (1) | AT395972B (en) |
AU (1) | AU591188B2 (en) |
BE (1) | BE905601A (en) |
CA (1) | CA1296335C (en) |
CH (1) | CH669787A5 (en) |
DE (1) | DE3634974A1 (en) |
DK (1) | DK491786A (en) |
ES (1) | ES2002036A6 (en) |
FI (1) | FI89164C (en) |
FR (1) | FR2591590B1 (en) |
GB (2) | GB8525321D0 (en) |
IE (1) | IE59466B1 (en) |
IL (2) | IL78432A (en) |
IT (1) | IT1205360B (en) |
NL (1) | NL8602575A (en) |
NO (1) | NO164895C (en) |
PT (1) | PT83531B (en) |
SE (1) | SE467541B (en) |
ZA (1) | ZA867772B (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3571808D1 (en) * | 1984-04-17 | 1989-08-31 | Glaxo Group Ltd | Ethanolamine compounds |
US5149698A (en) * | 1987-08-11 | 1992-09-22 | Glaxo Group Limited | Chloroaniline derivatives |
GB8718938D0 (en) * | 1987-08-11 | 1987-09-16 | Glaxo Group Ltd | Chemical compounds |
GB8718939D0 (en) * | 1987-08-11 | 1987-09-16 | Glaxo Group Ltd | Chemical compounds |
ES2039646T3 (en) * | 1987-11-13 | 1993-10-01 | Glaxo Group Limited | PHENETHANOLAMINE DERIVATIVES. |
ZA889405B (en) * | 1987-12-18 | 1989-12-27 | Glaxo Group Ltd | Ethanolamine derivatives |
DE3884363T2 (en) * | 1987-12-18 | 1994-01-20 | Glaxo Group Ltd | Ethanolamine derivatives. |
GB8808892D0 (en) * | 1988-04-15 | 1988-05-18 | British Bio Technology | Gene synthesis |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1618005A1 (en) * | 1966-09-22 | 1971-09-09 | Thomae Gmbh Dr K | Process for the preparation of new amino-dihalogen-phenyl-ethylamines |
DE2351281C3 (en) * | 1973-10-12 | 1981-07-30 | Dr. Karl Thomae Gmbh, 7950 Biberach | Aminophenylethanolamine derivatives, their production and use |
ZW6584A1 (en) * | 1983-04-18 | 1985-04-17 | Glaxo Group Ltd | Phenethanolamine derivatives |
DE3571808D1 (en) * | 1984-04-17 | 1989-08-31 | Glaxo Group Ltd | Ethanolamine compounds |
GB8426191D0 (en) * | 1984-10-17 | 1984-11-21 | Glaxo Holdings Ltd | Chemical compounds |
-
1985
- 1985-10-15 GB GB858525321A patent/GB8525321D0/en active Pending
-
1986
- 1986-04-08 IL IL78432A patent/IL78432A/en unknown
- 1986-10-14 CH CH4094/86A patent/CH669787A5/fr not_active IP Right Cessation
- 1986-10-14 NO NO864101A patent/NO164895C/en unknown
- 1986-10-14 DE DE19863634974 patent/DE3634974A1/en not_active Ceased
- 1986-10-14 GB GB8624630A patent/GB2182658B/en not_active Expired - Fee Related
- 1986-10-14 CA CA000520447A patent/CA1296335C/en not_active Expired - Fee Related
- 1986-10-14 IL IL80294A patent/IL80294A/en not_active IP Right Cessation
- 1986-10-14 FI FI864137A patent/FI89164C/en not_active IP Right Cessation
- 1986-10-14 IT IT48547/86A patent/IT1205360B/en active
- 1986-10-14 ES ES8602594A patent/ES2002036A6/en not_active Expired
- 1986-10-14 SE SE8604349A patent/SE467541B/en not_active IP Right Cessation
- 1986-10-14 ZA ZA867772A patent/ZA867772B/en unknown
- 1986-10-14 AU AU63959/86A patent/AU591188B2/en not_active Ceased
- 1986-10-14 IE IE270786A patent/IE59466B1/en not_active IP Right Cessation
- 1986-10-14 PT PT83531A patent/PT83531B/en not_active IP Right Cessation
- 1986-10-14 NL NL8602575A patent/NL8602575A/en not_active Application Discontinuation
- 1986-10-14 KR KR1019860008583A patent/KR870003970A/en not_active Application Discontinuation
- 1986-10-14 AT AT0273486A patent/AT395972B/en not_active IP Right Cessation
- 1986-10-14 JP JP61244002A patent/JPS62149651A/en active Pending
- 1986-10-14 DK DK491786A patent/DK491786A/en not_active Application Discontinuation
- 1986-10-15 BE BE0/217292A patent/BE905601A/en not_active IP Right Cessation
- 1986-10-15 FR FR868614314A patent/FR2591590B1/en not_active Expired - Fee Related
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: GLAXO GROUP LTD Effective date: 19941031 |