BE904846A - 11BETA-SUBSTITUTED STEROIDS USEFUL IN PARTICULAR IN THE TREATMENT OF HORMONO-DEPENDENT TUMORS AND METHOD FOR THE PRODUCTION THEREOF. - Google Patents
11BETA-SUBSTITUTED STEROIDS USEFUL IN PARTICULAR IN THE TREATMENT OF HORMONO-DEPENDENT TUMORS AND METHOD FOR THE PRODUCTION THEREOF.Info
- Publication number
- BE904846A BE904846A BE0/216722A BE216722A BE904846A BE 904846 A BE904846 A BE 904846A BE 0/216722 A BE0/216722 A BE 0/216722A BE 216722 A BE216722 A BE 216722A BE 904846 A BE904846 A BE 904846A
- Authority
- BE
- Belgium
- Prior art keywords
- 11beta
- treatment
- hormono
- production
- dependent tumors
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0066—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa
- C07J1/007—Estrane derivatives substituted in position 17 beta not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
- C07J1/0074—Esters
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Les stéroides 11beta-substitués sont des 3-oxo- ou 3-méthylène-4(5), 9(10)-oestradiènes de formule générale ci-dessous. Applications : Compositions pharmaceutiques utiles en médecine humaine ou vétérinaire, notamment comme agents anti-progestérone et antiglucocorticoide et dans le traitement des tumeurs hormono-dépendantes.The 11beta-substituted steroids are 3-oxo- or 3-methylene-4 (5), 9 (10) -oestradienes of the general formula below. Applications: Pharmaceutical compositions useful in human or veterinary medicine, in particular as anti-progesterone and anti-glucocorticoid agents and in the treatment of hormone-dependent tumors.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB858513723A GB8513723D0 (en) | 1985-05-31 | 1985-05-31 | 11-beta substituted steroids |
Publications (1)
Publication Number | Publication Date |
---|---|
BE904846A true BE904846A (en) | 1986-12-01 |
Family
ID=10579949
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE0/216722A BE904846A (en) | 1985-05-31 | 1986-05-30 | 11BETA-SUBSTITUTED STEROIDS USEFUL IN PARTICULAR IN THE TREATMENT OF HORMONO-DEPENDENT TUMORS AND METHOD FOR THE PRODUCTION THEREOF. |
Country Status (21)
Country | Link |
---|---|
JP (1) | JPS6212796A (en) |
KR (1) | KR860009035A (en) |
AU (1) | AU587031B2 (en) |
BE (1) | BE904846A (en) |
CH (1) | CH669385A5 (en) |
DE (1) | DE3617883A1 (en) |
DK (1) | DK251386A (en) |
ES (1) | ES8707972A1 (en) |
FI (1) | FI862278A (en) |
FR (1) | FR2582654B1 (en) |
GB (2) | GB8513723D0 (en) |
GR (1) | GR861405B (en) |
HU (1) | HU197925B (en) |
IL (1) | IL78957A (en) |
IT (1) | IT1190014B (en) |
NL (1) | NL8601387A (en) |
NZ (1) | NZ216325A (en) |
PT (1) | PT82665B (en) |
SE (1) | SE8602449L (en) |
SU (1) | SU1508963A3 (en) |
ZA (1) | ZA864065B (en) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3866410D1 (en) * | 1987-04-24 | 1992-01-09 | Akzo Nv | 11-ARYLESTRANDERIVATIVES AND 11-ARYLPREGNANDERIVATIVES. |
DE3878198T2 (en) * | 1987-12-12 | 1993-06-24 | Akzo Nv | 11-ARYLSTEROID DERIVATIVES. |
FR2665901B2 (en) * | 1989-02-24 | 1994-07-29 | Roussel Uclaf | NEW 19-NOR STEROUIDES HAVING IN THE 11BETA POSITION A CARBON CHAIN COMPRISING AN AMIDE FUNCTION, THEIR PREPARATION, THEIR APPLICATION AS MEDICAMENTS. |
FR2643638B1 (en) * | 1989-02-24 | 1991-06-14 | Roussel Uclaf | NOVEL 19-NOR STEROIDS HAVING IN THE 11BETA POSITION A CARBON CHAIN COMPRISING AN AMIDE OR CARBAMATE FUNCTION, THEIR PREPARATION METHOD AND INTERMEDIATES THEREOF, THEIR APPLICATION AS MEDICAMENTS AND THE PHARMACEUTICAL COMPOSITIONS CONTAINING THEM |
TWI265167B (en) * | 1999-11-29 | 2006-11-01 | Akzo Nobel Nv | 3-methylene steroid derivatives |
DE19961219A1 (en) * | 1999-12-15 | 2001-07-19 | Jenapharm Gmbh | 11beta-phenyltratriene derivatives with fluoroalkyl groups in the aromatic side chain, their preparation and pharmaceutical compositions containing these compounds |
TW200531977A (en) | 2004-03-25 | 2005-10-01 | Akzo Nobel Nv | Progesterone receptor modulators |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH488682A (en) * | 1965-07-30 | 1970-04-15 | Ciba Geigy | Process for the preparation of 4,9,11-trienes of the 19-nor-androstane series |
FR192F (en) * | 1965-10-22 | |||
FR5913M (en) * | 1965-12-02 | 1968-04-01 | ||
NL128375C (en) * | 1966-02-18 | |||
FR2054525B1 (en) * | 1969-07-28 | 1973-01-12 | Roussel Uclaf | |
FR2054527B1 (en) * | 1969-07-28 | 1973-06-08 | Roussel Uclaf | |
FR2377418A1 (en) * | 1977-01-13 | 1978-08-11 | Roussel Uclaf | NEW 4,9-DIENIC 11B-SUBSTITUTE STEROID DERIVATIVES, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICINAL PRODUCTS |
ZA8231B (en) * | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
FR2522328B1 (en) * | 1982-03-01 | 1986-02-14 | Roussel Uclaf | NEW PRODUCTS DERIVED FROM THE STRUCTURE 3-CETO 4,9 19-NOR STEROIDS, THEIR PREPARATION PROCESS AND THEIR APPLICATION AS MEDICAMENTS |
AU580843B2 (en) * | 1985-02-07 | 1989-02-02 | Schering Aktiengesellschaft | 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them |
-
1985
- 1985-05-31 GB GB858513723A patent/GB8513723D0/en active Pending
-
1986
- 1986-05-23 ES ES555298A patent/ES8707972A1/en not_active Expired
- 1986-05-27 GB GB08612866A patent/GB2175905B/en not_active Expired
- 1986-05-27 HU HU862228A patent/HU197925B/en not_active IP Right Cessation
- 1986-05-28 CH CH2152/86A patent/CH669385A5/de not_active IP Right Cessation
- 1986-05-28 IT IT20598/86A patent/IT1190014B/en active
- 1986-05-28 PT PT82665A patent/PT82665B/en not_active IP Right Cessation
- 1986-05-28 IL IL78957A patent/IL78957A/en unknown
- 1986-05-28 DE DE19863617883 patent/DE3617883A1/en not_active Withdrawn
- 1986-05-28 FR FR8607660A patent/FR2582654B1/en not_active Expired
- 1986-05-28 NZ NZ216325A patent/NZ216325A/en unknown
- 1986-05-29 NL NL8601387A patent/NL8601387A/en not_active Application Discontinuation
- 1986-05-29 SE SE8602449A patent/SE8602449L/en not_active Application Discontinuation
- 1986-05-29 GR GR861405A patent/GR861405B/en unknown
- 1986-05-29 AU AU58062/86A patent/AU587031B2/en not_active Ceased
- 1986-05-29 SU SU864027509A patent/SU1508963A3/en active
- 1986-05-29 FI FI862278A patent/FI862278A/en not_active Application Discontinuation
- 1986-05-29 DK DK251386A patent/DK251386A/en not_active Application Discontinuation
- 1986-05-30 BE BE0/216722A patent/BE904846A/en not_active IP Right Cessation
- 1986-05-30 JP JP61123893A patent/JPS6212796A/en active Pending
- 1986-05-30 ZA ZA864065A patent/ZA864065B/en unknown
- 1986-05-30 KR KR1019860004283A patent/KR860009035A/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
IT8620598A1 (en) | 1987-11-28 |
IL78957A0 (en) | 1986-09-30 |
ZA864065B (en) | 1987-01-28 |
PT82665B (en) | 1988-08-17 |
SE8602449L (en) | 1986-12-01 |
FI862278A0 (en) | 1986-05-29 |
ES555298A0 (en) | 1987-09-01 |
SE8602449D0 (en) | 1986-05-29 |
PT82665A (en) | 1986-06-01 |
FR2582654B1 (en) | 1988-06-03 |
CH669385A5 (en) | 1989-03-15 |
HUT44575A (en) | 1988-03-28 |
DK251386D0 (en) | 1986-05-29 |
FI862278A (en) | 1986-12-01 |
NZ216325A (en) | 1989-01-27 |
DE3617883A1 (en) | 1986-12-04 |
AU587031B2 (en) | 1989-08-03 |
AU5806286A (en) | 1986-12-04 |
GB8612866D0 (en) | 1986-07-02 |
SU1508963A3 (en) | 1989-09-15 |
NL8601387A (en) | 1986-12-16 |
IT1190014B (en) | 1988-02-10 |
DK251386A (en) | 1986-12-01 |
GB8513723D0 (en) | 1985-07-03 |
IT8620598A0 (en) | 1986-05-28 |
GB2175905B (en) | 1989-01-18 |
GB2175905A (en) | 1986-12-10 |
ES8707972A1 (en) | 1987-09-01 |
IL78957A (en) | 1990-11-29 |
JPS6212796A (en) | 1987-01-21 |
KR860009035A (en) | 1986-12-19 |
GR861405B (en) | 1986-09-26 |
HU197925B (en) | 1989-06-28 |
FR2582654A1 (en) | 1986-12-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE | Patent lapsed |
Owner name: FARMITALIA CARLO ERBA S.P.A. Effective date: 19910531 |