BE893707R - Azabicyclohexanes et procede de leur preparation - Google Patents

Azabicyclohexanes et procede de leur preparation

Info

Publication number
BE893707R
BE893707R BE0/208496A BE208496A BE893707R BE 893707 R BE893707 R BE 893707R BE 0/208496 A BE0/208496 A BE 0/208496A BE 208496 A BE208496 A BE 208496A BE 893707 R BE893707 R BE 893707R
Authority
BE
Belgium
Prior art keywords
azabicyclohexanes
preparation
Prior art date
Application number
BE0/208496A
Other languages
English (en)
Inventor
A C Osterberg
J W Epstein
H J Brabander
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Application granted granted Critical
Publication of BE893707R publication Critical patent/BE893707R/fr

Links

Classifications

    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03B—APPARATUS OR ARRANGEMENTS FOR TAKING PHOTOGRAPHS OR FOR PROJECTING OR VIEWING THEM; APPARATUS OR ARRANGEMENTS EMPLOYING ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ACCESSORIES THEREFOR
    • G03B19/00—Cameras
    • G03B19/18—Motion-picture cameras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, ***e
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/52—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring condensed with a ring other than six-membered

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
BE0/208496A 1981-07-01 1982-06-30 Azabicyclohexanes et procede de leur preparation BE893707R (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27936681A 1981-07-01 1981-07-01

Publications (1)

Publication Number Publication Date
BE893707R true BE893707R (fr) 1982-12-30

Family

ID=23068645

Family Applications (1)

Application Number Title Priority Date Filing Date
BE0/208496A BE893707R (fr) 1981-07-01 1982-06-30 Azabicyclohexanes et procede de leur preparation

Country Status (6)

Country Link
JP (1) JPS5813568A (fr)
BE (1) BE893707R (fr)
DE (1) DE3223463A1 (fr)
GR (1) GR76185B (fr)
IL (1) IL65843A (fr)
ZA (1) ZA824689B (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6372919B1 (en) 2001-01-11 2002-04-16 Dov Pharmaceutical, Inc. (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as an anti-depressant agent
US6569887B2 (en) 2001-08-24 2003-05-27 Dov Pharmaceuticals Inc. (−)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake
US8138377B2 (en) 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
US8765801B2 (en) 2004-08-18 2014-07-01 Euthymics Bioscience, Inc. Polymorphs of azabicyclohexane
US8877798B2 (en) 2005-07-27 2014-11-04 Neurovance, Inc. 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
US9393204B2 (en) 2002-07-31 2016-07-19 Ebi Life Sciences, Inc. Methods and compositions employing bicifadine for treating disability or functional impairment associated with acute pain, chronic pain, or neuropathic disorders
US9527813B2 (en) 2006-04-28 2016-12-27 Euthymics Bioscience, Inc. Process for the synthesis of (+) and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0114033B1 (fr) * 1982-12-21 1988-10-12 Ciba-Geigy Ag Azabicycloalcanes substitués, leur utilisation, préparations pharmaceutiques contenant ces composés et procédé pour la préparation de ces composés
US5302752A (en) * 1989-10-30 1994-04-12 Ethyl Corporation Acetic acid derivatives and their production
GB0507602D0 (en) * 2005-04-14 2005-05-18 Glaxo Group Ltd Compounds
EP1904059A2 (fr) * 2005-07-21 2008-04-02 Wyeth a Corporation of the State of Delaware Methode de traitement de troubles et d'affections du systeme nerveux
GB0517175D0 (en) * 2005-08-22 2005-09-28 Glaxo Group Ltd Compounds
CA2834713A1 (fr) * 2010-12-03 2012-06-07 Anthony Alexander Mckinney Preparation et utilisation du (+)-1-(3,4-dichlorophenyl)-3-azabicyclo- [3.1.0]hexane dans le traitement des pathologies affectees par les neurotransmetteurs de type monoamine
BR112021020883A2 (pt) * 2019-05-01 2022-04-19 Boehringer Ingelheim Int Formas sólidas de um inibidor de glyt1

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4131611A (en) * 1975-07-31 1978-12-26 American Cyanamid Company Azabicyclohexanes
GR72713B (fr) * 1976-09-15 1983-12-01 American Cyanamid Co

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6372919B1 (en) 2001-01-11 2002-04-16 Dov Pharmaceutical, Inc. (+)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as an anti-depressant agent
US6569887B2 (en) 2001-08-24 2003-05-27 Dov Pharmaceuticals Inc. (−)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake
US6716868B2 (en) 2001-08-24 2004-04-06 Dov Pharmaceutical Inc (-)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake inhibitor
US7041835B2 (en) 2001-08-24 2006-05-09 Dor Pharmaceutical, Inc. (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake inhibitor
US7081471B2 (en) 2001-08-24 2006-07-25 Dov Pharmaceutical, Inc. (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake inhibitor
US7098230B2 (en) 2001-08-24 2006-08-29 Dov Pharmaceutical, Inc. (-)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane, compositions thereof, and uses as a dopamine-reuptake inhibitor
US9393204B2 (en) 2002-07-31 2016-07-19 Ebi Life Sciences, Inc. Methods and compositions employing bicifadine for treating disability or functional impairment associated with acute pain, chronic pain, or neuropathic disorders
US8765801B2 (en) 2004-08-18 2014-07-01 Euthymics Bioscience, Inc. Polymorphs of azabicyclohexane
US9139521B2 (en) 2004-08-18 2015-09-22 Euthymics Bioscience, Inc. Polymorphs of azabicyclohexane
US8877798B2 (en) 2005-07-27 2014-11-04 Neurovance, Inc. 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
US9205074B2 (en) 2005-07-27 2015-12-08 Neurovance, Inc. 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
US9737506B2 (en) 2005-07-27 2017-08-22 Neurovance, Inc. 1-aryl-3-azabicyclo[3.1.0]hexanes: preparation and use to treat neuropsychiatric disorders
US9527813B2 (en) 2006-04-28 2016-12-27 Euthymics Bioscience, Inc. Process for the synthesis of (+) and (−)-1-(3,4-dichlorophenyl)-3-azabicyclo[3.1.0]hexane
US8138377B2 (en) 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
US9597315B2 (en) 2007-06-06 2017-03-21 Euthymics Bioscience, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments

Also Published As

Publication number Publication date
DE3223463A1 (de) 1983-05-05
DE3223463C2 (fr) 1991-05-02
JPS5813568A (ja) 1983-01-26
IL65843A (en) 1986-12-31
GR76185B (fr) 1984-08-03
ZA824689B (en) 1983-04-27
IL65843A0 (en) 1982-08-31

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Legal Events

Date Code Title Description
RE Patent lapsed

Owner name: AMERICAN CYANAMID CY

Effective date: 19920930