BE871769A - Derives de quinazoline, leur procede de production et composition pharmaceutique les contenant - Google Patents
Derives de quinazoline, leur procede de production et composition pharmaceutique les contenantInfo
- Publication number
- BE871769A BE871769A BE191542A BE191542A BE871769A BE 871769 A BE871769 A BE 871769A BE 191542 A BE191542 A BE 191542A BE 191542 A BE191542 A BE 191542A BE 871769 A BE871769 A BE 871769A
- Authority
- BE
- Belgium
- Prior art keywords
- pharmaceutical composition
- composition containing
- production process
- quinazoline derivatives
- quinazoline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/40—Acylated substituent nitrogen atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
- C07D211/28—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms to which a second hetero atom is attached
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/36—Radicals substituted by singly-bound nitrogen atoms
- C07D213/42—Radicals substituted by singly-bound nitrogen atoms having hetero atoms attached to the substituent nitrogen atom
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Hospice & Palliative Care (AREA)
- Heart & Thoracic Surgery (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Pyridine Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4566977 | 1977-11-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BE871769A true BE871769A (fr) | 1979-05-03 |
Family
ID=10438111
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BE191542A BE871769A (fr) | 1977-11-03 | 1978-11-03 | Derives de quinazoline, leur procede de production et composition pharmaceutique les contenant |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US4188391A (es) |
| JP (1) | JPS5498786A (es) |
| AR (2) | AR221851A1 (es) |
| AT (1) | AT366043B (es) |
| AU (1) | AU506317B2 (es) |
| BE (1) | BE871769A (es) |
| CA (1) | CA1086735A (es) |
| CH (1) | CH637130A5 (es) |
| DE (1) | DE2847622A1 (es) |
| DK (1) | DK488078A (es) |
| ES (2) | ES474763A1 (es) |
| FI (1) | FI63934C (es) |
| FR (1) | FR2407926A1 (es) |
| HK (1) | HK94184A (es) |
| IE (1) | IE47996B1 (es) |
| IL (1) | IL55845A (es) |
| IT (1) | IT1101287B (es) |
| KE (1) | KE3351A (es) |
| LU (1) | LU80461A1 (es) |
| MY (1) | MY8500284A (es) |
| NL (1) | NL174144C (es) |
| PH (1) | PH14693A (es) |
| PT (1) | PT68733A (es) |
| SE (1) | SE7811323L (es) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4489075A (en) * | 1982-05-15 | 1984-12-18 | Pfizer Inc. | Cyclic sulfonamidoalkyl substituted 4-piperidinoquinazoline cardiac stimulants |
| JPS61215389A (ja) * | 1985-03-20 | 1986-09-25 | Kyowa Hakko Kogyo Co Ltd | キナゾリン誘導体およびそれを含有する強心剤 |
| US5614627A (en) * | 1993-09-10 | 1997-03-25 | Eisai Co., Ltd. | Quinazoline compounds |
| JP4028894B2 (ja) * | 1996-08-09 | 2007-12-26 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | ベンゾピペリジン誘導体 |
| EP2275095A3 (en) | 2005-08-26 | 2011-08-17 | Braincells, Inc. | Neurogenesis by muscarinic receptor modulation |
| EP2258358A3 (en) | 2005-08-26 | 2011-09-07 | Braincells, Inc. | Neurogenesis with acetylcholinesterase inhibitor |
| JP2009512711A (ja) | 2005-10-21 | 2009-03-26 | ブレインセルス，インコーポレイティド | Ｐｄｅ阻害による神経新生の調節 |
| CA2625210A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
| US20100216734A1 (en) * | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
| US20070244143A1 (en) * | 2006-03-08 | 2007-10-18 | Braincells, Inc | Modulation of neurogenesis by nootropic agents |
| US20100009983A1 (en) * | 2006-05-09 | 2010-01-14 | Braincells, Inc. | 5 ht receptor mediated neurogenesis |
| AU2007249399A1 (en) | 2006-05-09 | 2007-11-22 | Braincells, Inc. | Neurogenesis by modulating angiotensin |
| JP2009536667A (ja) * | 2006-05-09 | 2009-10-15 | ブレインセルス，インコーポレイティド | ５ｈｔ受容体介在性の神経新生 |
| KR20090064418A (ko) * | 2006-09-08 | 2009-06-18 | 브레인셀즈 인코퍼레이션 | 4-아실아미노피리딘 유도체 포함 조합물 |
| WO2008036678A2 (en) * | 2006-09-19 | 2008-03-27 | Braincells, Inc. | Combination comprising a peroxisome proliferator activated receptor agent and a second neurogenic agent for treating a nervous system disorder, increasing neurodifferentiation and increasing neurogenesis |
| US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
| MX2009003313A (es) * | 2006-10-06 | 2009-04-09 | Bausch & Lomb | Acidos quinolona carboxilicos, derivados de los mismos, procesos para su preparacion y su uso como agentes antibacterianos. |
| US7632944B2 (en) * | 2007-01-24 | 2009-12-15 | Bausch & Lomb Incorporated | Quinolone carboxylic acids, derivatives thereof, and methods of making and using same |
| WO2010099217A1 (en) | 2009-02-25 | 2010-09-02 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
| WO2013106547A1 (en) | 2012-01-10 | 2013-07-18 | President And Fellows Of Harvard College | Beta-cell replication promoting compounds and methods of their use |
| CN113924092A (zh) * | 2019-03-19 | 2022-01-11 | 斯汀格瑞治疗股份有限公司 | 喹啉和喹唑啉化合物以及其使用方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3812127A (en) * | 1966-10-31 | 1974-05-21 | Pfizer | 4-(quinolin-4-yl)piperazine-1-carboxylic acid esters |
| GB1199768A (en) * | 1966-10-31 | 1970-07-22 | Pfizer & Co C | Nitrogen Heterocycles and process for their preparation |
| US3517005A (en) * | 1967-10-26 | 1970-06-23 | Pfizer & Co C | Certain 2- and 4-substituted quinazolines |
| GB1460389A (en) * | 1974-07-25 | 1977-01-06 | Pfizer Ltd | 4-substituted quinazoline cardiac stimulants |
-
1978
- 1978-10-24 CA CA314,062A patent/CA1086735A/en not_active Expired
- 1978-10-26 US US05/954,931 patent/US4188391A/en not_active Expired - Lifetime
- 1978-10-30 PH PH21751A patent/PH14693A/en unknown
- 1978-10-31 LU LU80461A patent/LU80461A1/fr unknown
- 1978-11-01 SE SE7811323A patent/SE7811323L/xx unknown
- 1978-11-01 NL NLAANVRAGE7810865,A patent/NL174144C/xx not_active IP Right Cessation
- 1978-11-01 DK DK488078A patent/DK488078A/da not_active Application Discontinuation
- 1978-11-01 CH CH1125378A patent/CH637130A5/de not_active IP Right Cessation
- 1978-11-01 FI FI783325A patent/FI63934C/fi not_active IP Right Cessation
- 1978-11-01 AR AR274310A patent/AR221851A1/es active
- 1978-11-01 IL IL55845A patent/IL55845A/xx unknown
- 1978-11-02 ES ES474763A patent/ES474763A1/es not_active Expired
- 1978-11-02 IT IT29368/78A patent/IT1101287B/it active
- 1978-11-02 AT AT0783878A patent/AT366043B/de not_active IP Right Cessation
- 1978-11-02 AU AU41277/78A patent/AU506317B2/en not_active Expired
- 1978-11-02 IE IE2165/78A patent/IE47996B1/en unknown
- 1978-11-02 DE DE19782847622 patent/DE2847622A1/de not_active Ceased
- 1978-11-02 JP JP13569678A patent/JPS5498786A/ja active Granted
- 1978-11-02 FR FR7831062A patent/FR2407926A1/fr active Granted
- 1978-11-02 PT PT68733A patent/PT68733A/pt unknown
- 1978-11-03 BE BE191542A patent/BE871769A/xx not_active IP Right Cessation
-
1979
- 1979-04-27 ES ES480053A patent/ES480053A1/es not_active Expired
- 1979-11-01 AR AR278733A patent/AR221251A1/es active
-
1983
- 1983-11-21 KE KE3351A patent/KE3351A/xx unknown
-
1984
- 1984-11-29 HK HK941/84A patent/HK94184A/xx unknown
-
1985
- 1985-12-30 MY MY284/85A patent/MY8500284A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AR221851A1 (es) | 1981-03-31 |
| MY8500284A (en) | 1985-12-31 |
| FR2407926A1 (fr) | 1979-06-01 |
| CA1086735A (en) | 1980-09-30 |
| IL55845A0 (en) | 1979-01-31 |
| AU4127778A (en) | 1979-05-17 |
| NL7810865A (nl) | 1979-05-07 |
| AU506317B2 (en) | 1979-12-20 |
| NL174144B (nl) | 1983-12-01 |
| DK488078A (da) | 1979-05-04 |
| PH14693A (en) | 1981-11-10 |
| JPS566428B2 (es) | 1981-02-10 |
| HK94184A (en) | 1984-12-07 |
| IT7829368A0 (it) | 1978-11-02 |
| NL174144C (nl) | 1984-05-01 |
| AR221251A1 (es) | 1981-01-15 |
| CH637130A5 (de) | 1983-07-15 |
| LU80461A1 (fr) | 1980-05-07 |
| IE47996B1 (en) | 1984-08-22 |
| SE7811323L (sv) | 1979-05-04 |
| ES480053A1 (es) | 1980-07-16 |
| FI783325A (fi) | 1979-05-04 |
| ES474763A1 (es) | 1980-12-16 |
| FR2407926B1 (es) | 1982-11-12 |
| FI63934B (fi) | 1983-05-31 |
| DE2847622A1 (de) | 1979-05-31 |
| US4188391A (en) | 1980-02-12 |
| IL55845A (en) | 1982-07-30 |
| PT68733A (en) | 1978-12-01 |
| IT1101287B (it) | 1985-09-28 |
| FI63934C (fi) | 1983-09-12 |
| JPS5498786A (en) | 1979-08-03 |
| KE3351A (en) | 1983-12-16 |
| AT366043B (de) | 1982-03-10 |
| ATA783878A (de) | 1981-07-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RE | Patent lapsed |
Owner name: PFIZER CORP. Effective date: 19841103 |