BE844344A - Procede de cyclisation pour la formation d'un noyau cepheme - Google Patents
Procede de cyclisation pour la formation d'un noyau cephemeInfo
- Publication number
- BE844344A BE844344A BE169089A BE169089A BE844344A BE 844344 A BE844344 A BE 844344A BE 169089 A BE169089 A BE 169089A BE 169089 A BE169089 A BE 169089A BE 844344 A BE844344 A BE 844344A
- Authority
- BE
- Belgium
- Prior art keywords
- cepheme
- core
- formation
- cycling process
- cycling
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/02—Preparation
- C07D501/08—Preparation by forming the ring or condensed ring systems
- C07D501/10—Preparation by forming the ring or condensed ring systems from compounds containing the penicillin ring system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/06—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D205/08—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
- C07D205/09—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4
- C07D205/095—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams with a sulfur atom directly attached in position 4 and with a nitrogen atom directly attached in position 3
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP50089915A JPS5214789A (en) | 1975-07-22 | 1975-07-22 | Process for preparing 3-substiuted cephem compounds by ring closure |
Publications (1)
Publication Number | Publication Date |
---|---|
BE844344A true BE844344A (fr) | 1976-11-16 |
Family
ID=13983995
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE169089A BE844344A (fr) | 1975-07-22 | 1976-07-20 | Procede de cyclisation pour la formation d'un noyau cepheme |
Country Status (12)
Country | Link |
---|---|
US (1) | US4066641A (fr) |
JP (1) | JPS5214789A (fr) |
BE (1) | BE844344A (fr) |
CA (1) | CA1068259A (fr) |
CH (1) | CH623824A5 (fr) |
DE (2) | DE2660607C2 (fr) |
ES (1) | ES450005A1 (fr) |
FR (1) | FR2318642A1 (fr) |
GB (1) | GB1533795A (fr) |
IE (1) | IE43500B1 (fr) |
IL (1) | IL50097A (fr) |
NL (1) | NL186009C (fr) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH605997A5 (fr) * | 1974-08-30 | 1978-10-13 | Ciba Geigy Ag | |
CA1136132A (fr) * | 1975-02-17 | 1982-11-23 | Teruji Tsuji | Cyclisation pour fermer des noyaux cephem et intermediaires ainsi obtenus |
US4550162A (en) * | 1975-02-20 | 1985-10-29 | Ciba-Geigy Corporation | Process for the manufacture of enol derivatives |
AT342197B (de) * | 1975-02-20 | 1978-03-28 | Ciba Geigy Ag | Neues verfahren zur herstellung von 3-cephemverbindungen |
US4150156A (en) * | 1975-11-21 | 1979-04-17 | Merck & Co., Inc. | 7-(Substituted methyl)-3-(substituted thio)-cephalosporins, derivatives and pharmaceutical compositions containing them |
GB1575415A (en) * | 1976-12-31 | 1980-09-24 | Connlab Holdings Ltd | Process for preparing 2-acyloxymethyl-penams and 3-acloxycephams |
US4211702A (en) * | 1979-02-01 | 1980-07-08 | Eli Lilly And Company | Process for preparation of penicillin and cephalosporin imino halides |
US4291031A (en) * | 1979-02-19 | 1981-09-22 | Fujisawa Pharmaceutical Co., Ltd. | 3-Phosphonocephalosporanic acid derivatives, and pharmaceutical composition comprising the same |
CA1148938A (fr) * | 1979-05-08 | 1983-06-28 | John R. Corfield | Preparation de cephalosporines et produits intermediaires utilises a cette fin |
US4335240A (en) * | 1980-04-07 | 1982-06-15 | Eli Lilly And Company | Process for cyclization |
US4302391A (en) * | 1980-04-07 | 1981-11-24 | Eli Lilly And Company | Unsymmetrical azetidinone aldehyde disulfides and process |
US4293493A (en) * | 1980-04-07 | 1981-10-06 | Eli Lilly And Company | Azetidinone alcohol disulfides and process for cyclization |
EP0065488B1 (fr) * | 1981-05-19 | 1985-08-14 | Ciba-Geigy Ag | Procédé de préparation de dérivés de 4-thio-azétidinone |
US5247073A (en) * | 1991-01-18 | 1993-09-21 | Eli Lilly And Company | 7-(Amino or protected amino)-3-thioheterobicyclic cephalosporins |
IL100576A (en) * | 1991-01-18 | 1995-11-27 | Eli Lilley And Company | Cephalosporin antibiotics |
JP3195371B2 (ja) * | 1991-03-11 | 2001-08-06 | 大塚化学株式会社 | セフエム誘導体の製造法 |
US5162521A (en) * | 1991-06-06 | 1992-11-10 | Bristol-Myers Squibb Company | Processes for making cephems from allenylazetidinone derivatives |
ATE208374T1 (de) * | 1992-02-18 | 2001-11-15 | Otsuka Kagaku Kk | Beta-laktam und cepham verbindungen und ihre herstellung |
JPH09511738A (ja) * | 1994-04-01 | 1997-11-25 | マイクロサイド・ファーマシューティカルズ・インコーポレーテッド | セファロスポリン抗生物質 |
US5688786A (en) * | 1994-04-01 | 1997-11-18 | Microcide Pharmaceuticals, Inc. | β-lactam antibiotics |
US5698547A (en) * | 1994-04-01 | 1997-12-16 | Microcide Pharmaceuticals, Inc. | Cephalosporin antibiotics |
JPH10510258A (ja) * | 1994-12-09 | 1998-10-06 | 藤沢薬品工業株式会社 | セフェム化合物およびその医薬用途 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3944545A (en) * | 1972-05-10 | 1976-03-16 | Eli Lilly And Company | Process for preparing desacetoxycephalosporins |
GB1451459A (en) * | 1972-10-20 | 1976-10-06 | Fujisawa Pharamceutical Co Ltd | Process for preparing 3-alkyl-3-cephem-4-carboxylic acids and intermediates thereof |
-
1975
- 1975-07-22 JP JP50089915A patent/JPS5214789A/ja active Pending
-
1976
- 1976-07-14 CA CA256,915A patent/CA1068259A/fr not_active Expired
- 1976-07-20 GB GB30148/76A patent/GB1533795A/en not_active Expired
- 1976-07-20 BE BE169089A patent/BE844344A/fr not_active IP Right Cessation
- 1976-07-21 ES ES450005A patent/ES450005A1/es not_active Expired
- 1976-07-21 DE DE2660607A patent/DE2660607C2/de not_active Expired
- 1976-07-21 US US05/707,288 patent/US4066641A/en not_active Expired - Lifetime
- 1976-07-21 FR FR7622258A patent/FR2318642A1/fr active Granted
- 1976-07-21 DE DE2632872A patent/DE2632872C2/de not_active Expired
- 1976-07-21 IL IL50097A patent/IL50097A/xx unknown
- 1976-07-22 CH CH942576A patent/CH623824A5/de not_active IP Right Cessation
- 1976-07-22 NL NLAANVRAGE7608146,A patent/NL186009C/xx not_active IP Right Cessation
- 1976-07-22 IE IE1627/76A patent/IE43500B1/en unknown
Also Published As
Publication number | Publication date |
---|---|
ES450005A1 (es) | 1977-07-16 |
CA1068259A (fr) | 1979-12-18 |
DE2632872A1 (de) | 1977-02-10 |
IL50097A (en) | 1982-05-31 |
FR2318642B1 (fr) | 1979-10-12 |
FR2318642A1 (fr) | 1977-02-18 |
IE43500L (en) | 1977-01-22 |
IE43500B1 (en) | 1981-03-11 |
US4066641A (en) | 1978-01-03 |
IL50097A0 (en) | 1976-09-30 |
DE2632872C2 (de) | 1982-05-19 |
GB1533795A (en) | 1978-11-29 |
NL186009B (nl) | 1990-04-02 |
DE2660607C2 (de) | 1984-10-25 |
CH623824A5 (fr) | 1981-06-30 |
JPS5214789A (en) | 1977-02-03 |
NL7608146A (nl) | 1977-01-25 |
NL186009C (nl) | 1990-09-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
BE844344A (fr) | Procede de cyclisation pour la formation d'un noyau cepheme | |
PT64713A (fr) | Procede pour l'epoxydation | |
BE839140A (fr) | Procede pour l'obtention de n-acyl-l-methionine | |
RO72349A (fr) | Procede pour la preparation des derives d'imidazole a action pharmacologique | |
FR2336971A1 (fr) | Procede de formation de monocristaux d'halogenures alcalins | |
BE850383A (fr) | Procede ameliore pour le dosage de l'alcoolemie | |
RO66216A (fr) | Procede pour la production d'energie | |
BE842232A (fr) | Procede pour la preparation d'un compose formyle | |
RO84686A (fr) | Procede pour la preparation du procede a du-1-triazolyle-styrenes-1-substitus | |
BE852324A (fr) | Procede de production de nouveaux composes antigonistes d'histamine-h2 | |
BE835023A (fr) | Procede ameliore pour produire de l'urokinase | |
FR2326399A1 (fr) | Procede de production d'un alcane-polyol | |
FR2348177A1 (fr) | Procede pour l'orthoalcoylation des phenols | |
BE871961A (fr) | Procede ameliore pour la production d'alkylene-glycols | |
BE845676A (fr) | Procede pour la fabrication d'un tube cathodique devant reproduire des images colorees, et tube cathodique fabrique de la sorte | |
FR2352879A1 (fr) | Procede pour la production d' | |
FR2320927A1 (fr) | Procede pour l'obtention d'a,a,a,a',a', pentachloro-o-xylene | |
FR2322128A1 (fr) | Procede pour l'obtention d'aminoacetaldehyde acetals | |
BE856989A (fr) | Procede pour la preparation d'un nouvel alcaloide du type vincamine | |
FR2324350A1 (fr) | Procede pour la separation d'isotopes | |
FR2305417A1 (fr) | Procede pour l'obtention d'halogenophenols | |
FR2346345A1 (fr) | Procede pour l'obtention de 3-chlorophtalide | |
BE845050A (fr) | Procede pour la production d'aminomethyl-2-ethyl-1-pyrrolidine | |
BE861383A (fr) | Procede pour la preparation d'esters | |
RO71026A (fr) | Procede pour l'obtention d'escine cristallise |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RE20 | Patent expired |
Owner name: SHIONOGI & CO. LTD Effective date: 19960720 |