BE812688R - Agents cardiovasculaires a base de thiazoles - Google Patents

Agents cardiovasculaires a base de thiazoles

Info

Publication number: BE812688R
Authority: BE; Belgium
Prior art keywords: thiazola; cardiovascular agents; based cardiovascular; agents; cardiovascular
Prior art date: 1971-10-27

Application number

BE142328A

Other languages

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1971-10-27

Filing date

1974-03-22

Publication date

1974-09-23

1972-09-15 Priority claimed from US00289730A external-priority patent/US3850945A/en

1974-03-22 Application filed filed Critical

1974-09-23 Application granted granted Critical

1974-09-23 Publication of BE812688R publication Critical patent/BE812688R/fr

Links

229940125692 cardiovascular agent Drugs 0.000 title 1
239000002327 cardiovascular agent Substances 0.000 title 1
IMCGHZIGRANKHV-AJNGGQMLSA-N tert-butyl (3s,5s)-2-oxo-5-[(2s,4s)-5-oxo-4-propan-2-yloxolan-2-yl]-3-propan-2-ylpyrrolidine-1-carboxylate Chemical compound O1C(=O)[C@H](C(C)C)C[C@H]1[C@H]1N(C(=O)OC(C)(C)C)C(=O)[C@H](C(C)C)C1 IMCGHZIGRANKHV-AJNGGQMLSA-N 0.000 title 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/36—Sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/40—Unsubstituted amino or imino radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/44—Acylated amino or imino radicals
- C07D277/48—Acylated amino or imino radicals by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof, e.g. carbonylguanidines
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/54—Nitrogen and either oxygen or sulfur atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/56—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/58—Nitro radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Animal Behavior & Ethology (AREA)
Epidemiology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Thiazole And Isothizaole Compounds (AREA)

BE142328A 1971-10-27 1974-03-22 Agents cardiovasculaires a base de thiazoles BE812688R (fr)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US19317271A	1971-10-27	1971-10-27
US00289730A US3850945A (en)	1971-10-27	1972-09-15	3-thiazol-2'-oxy-aminopropanol cardiovascular agents
US34394573A	1973-03-22	1973-03-22
US451179A US3897441A (en)	1971-10-27	1974-03-14	Certain thiazole-carboxamides and acylamino-thiazoles

Publications (1)

Publication Number	Publication Date
BE812688R true BE812688R (fr)	1974-09-23

Family

ID=27497978

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
BE142328A BE812688R (fr)	1971-10-27	1974-03-22	Agents cardiovasculaires a base de thiazoles

Country Status (6)

Country	Link
US (1)	US3897441A (fr)
BE (1)	BE812688R (fr)
DE (1)	DE2413937A1 (fr)
FR (1)	FR2306692A2 (fr)
GB (3)	GB1460532A (fr)
NL (1)	NL7403852A (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2289189A1 (fr) *	1974-10-29	1976-05-28	Roussel Uclaf	Nouveaux derives d'acides 2-hydroxyalkyl thiazol 5-carboxyliques, leur procede de preparation et leur application comme medicaments
US4064258A (en) *	1976-07-19	1977-12-20	Syntex (U.S.A.) Inc.	Thiazole cardiovascular agents
US4119718A (en) *	1977-05-02	1978-10-10	Merck & Co., Inc.	3-Amino-2-oxy-propoxy-substituted isothiazoles
US4259341A (en) *	1977-06-01	1981-03-31	Merck & Co., Inc.	Di- and tri-substituted thiazoles
US4123550A (en) *	1977-10-31	1978-10-31	Syntex (U.S.A.) Inc.	Bicyclo[3.1.0]hexylethylaminocarbonyl-substituted heteroaryl cardiovascular agents
US4477460A (en) *	1982-10-19	1984-10-16	Syntex (U.S.A.) Inc.	Topical treatment of ocular hypertension
CA2450073C (fr)	2001-07-25	2017-08-29	Biomarin Pharmaceutical Inc.	Compositions et procedes de modulation du transport a travers la barriere hematho-encephalique
CN102379684B (zh)	2005-04-28	2014-11-19	普罗透斯数字保健公司	药物信息***
JP2010503710A (ja)	2006-09-18	2010-02-04	ラプトールファーマシューティカルインコーポレイテッド	受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
PT3395372T (pt)	2009-02-20	2022-05-05	Enhanx Biopharm Inc	Sistema de entrega de medicamentos à base de glutationa
WO2010129819A2 (fr)	2009-05-06	2010-11-11	Laboratory Skin Care, Inc.	Compositions pour libération dermique comprenant des complexes principe actif-particule de phosphate de calcium et procédés d'utilisation associés
US20120077778A1 (en)	2010-09-29	2012-03-29	Andrea Bourdelais	Ladder-Frame Polyether Conjugates

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1047927A (en) *	1964-03-09	1966-11-09	Ici Ltd	Alkanolamine derivatives
US3514465A (en) *	1966-12-30	1970-05-26	Degussa	Certain thiazolyl- and pyridinylaminoketones
US3803160A (en) *	1970-06-23	1974-04-09	Ciba Geigy Corp	2-aminoalkoxy-4-phenyl-thiazoles salts
US3803161A (en) *	1971-03-17	1974-04-09	American Home Prod	2-substituted-4,5,6,7-tetrahydrobenzothiazole-4-carboxylic acids and their alkyl esters

1974
- 1974-03-14 US US451179A patent/US3897441A/en not_active Expired - Lifetime
- 1974-03-21 GB GB1270774A patent/GB1460532A/en not_active Expired
- 1974-03-21 GB GB4824875A patent/GB1460533A/en not_active Expired
- 1974-03-21 NL NL7403852A patent/NL7403852A/xx not_active Application Discontinuation
- 1974-03-21 FR FR7409754A patent/FR2306692A2/fr active Granted
- 1974-03-21 GB GB4825075A patent/GB1460534A/en not_active Expired
- 1974-03-22 DE DE2413937A patent/DE2413937A1/de active Pending
- 1974-03-22 BE BE142328A patent/BE812688R/fr active

Also Published As

Publication number	Publication date
GB1460534A (en)	1977-01-06
GB1460533A (en)	1977-01-06
DE2413937A1 (de)	1974-09-26
FR2306692B2 (fr)	1979-05-25
US3897441A (en)	1975-07-29
GB1460532A (en)	1977-01-06
NL7403852A (fr)	1974-09-24
FR2306692A2 (fr)	1976-11-05

Publication	Publication Date	Title
IT947259B (it)	1973-05-21	Dispositivo di sollevamento a depressione
BE788295A (fr)	1973-03-01	Vinyl-halomethyl-s-triazines a groupement
BE785475R (fr)	1972-10-16	Circulateur a large
BR7203253D0 (pt)	1973-05-03	Um aparelho alceador
IT962624B (it)	1973-12-31	Cesso a cassa settica
BE781481A (fr)	1972-07-17	Elevateur a depression
AT354588B (de)	1979-01-10	Detergensmittel
AR192257A1 (es)	1973-02-08	Un dentifrico
BE790569A (fr)	1973-04-26	Agents cardiovasculaires a base de thiazoles
BR7202219D0 (pt)	1973-06-07	Um armario
SU446974A3 (ru)	1974-10-15	Моющее средство
BE812688R (fr)	1974-09-23	Agents cardiovasculaires a base de thiazoles
BE812689R (fr)	1974-09-23	Agents cardiovasculaires a base de thiazoles
BR7205823D0 (pt)	1973-09-25	Um conjunto de braco limpa-para-brisa
AT320106B (de)	1975-01-27	Detergensmittel
SE373600C (sv)	1980-03-17	Detergentkomposition
IT947209B (it)	1973-05-21	Copolimeri a blocchi ossidrilati
BR7204817D0 (pt)	1973-05-31	Composicoes a base de fenilarsenoditio
BR7204278D0 (pt)	1973-05-10	Um multiplenor
BE779272A (fr)	1972-08-11	Matieres a base de poly-(diorgano-siloxanes)
AT378661B (de)	1985-09-10	Vierkreiselige heuwerbungsmaschine
AR193246A1 (es)	1973-04-11	Un dentifrico
IT1045032B (it)	1980-04-21	Breicidi a base di etebi ciclici
SE388462B (sv)	1976-10-04	Deplacementmaskin
BE783311A (fr)	1972-09-01	Alliage a base de molybdene