AUPS120902A0 - Iron chelators as anti-proliferative agents against tumour cells - Google Patents
Iron chelators as anti-proliferative agents against tumour cellsInfo
- Publication number
- AUPS120902A0 AUPS120902A0 AUPS1209A AUPS120902A AUPS120902A0 AU PS120902 A0 AUPS120902 A0 AU PS120902A0 AU PS1209 A AUPS1209 A AU PS1209A AU PS120902 A AUPS120902 A AU PS120902A AU PS120902 A0 AUPS120902 A0 AU PS120902A0
- Authority
- AU
- Australia
- Prior art keywords
- tumour cells
- agents against
- proliferative agents
- iron chelators
- against tumour
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/88—Nicotinoylhydrazones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
- A61K31/175—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine having the group, >N—C(O)—N=N— or, e.g. carbonohydrazides, carbazones, semicarbazides, semicarbazones; Thioanalogues thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/72—Hydrazones
- C07C251/86—Hydrazones having doubly-bound carbon atoms of hydrazone groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/06—Compounds containing any of the groups, e.g. semicarbazides
- C07C281/08—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones
- C07C281/14—Compounds containing any of the groups, e.g. semicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. semicarbazones the carbon atom being further bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C337/00—Derivatives of thiocarbonic acids containing functional groups covered by groups C07C333/00 or C07C335/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C337/06—Compounds containing any of the groups, e.g. thiosemicarbazides
- C07C337/08—Compounds containing any of the groups, e.g. thiosemicarbazides the other nitrogen atom being further doubly-bound to a carbon atom, e.g. thiosemicarbazones
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPS1209A AUPS120902A0 (en) | 2002-03-19 | 2002-03-19 | Iron chelators as anti-proliferative agents against tumour cells |
AU2003209845A AU2003209845A1 (en) | 2002-03-19 | 2003-03-19 | Naphthylsemicarbazone, naphthylhydrazone, naphthylthiosemicarbazone, and naphthylthiohydrazone compounds and therapeutic use thereof |
PCT/AU2003/000328 WO2003078386A1 (en) | 2002-03-19 | 2003-03-19 | Naphthylsemicarbazone, naphthylhydrazone, naphthylthiosemicarbazone, and naphthylthiohydrazone compounds and therapeutic use thereof |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AUPS1209A AUPS120902A0 (en) | 2002-03-19 | 2002-03-19 | Iron chelators as anti-proliferative agents against tumour cells |
Publications (1)
Publication Number | Publication Date |
---|---|
AUPS120902A0 true AUPS120902A0 (en) | 2002-04-18 |
Family
ID=3834806
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AUPS1209A Abandoned AUPS120902A0 (en) | 2002-03-19 | 2002-03-19 | Iron chelators as anti-proliferative agents against tumour cells |
Country Status (2)
Country | Link |
---|---|
AU (1) | AUPS120902A0 (en) |
WO (1) | WO2003078386A1 (en) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2046122A4 (en) * | 2006-07-24 | 2009-12-23 | Univ Maryland | Heme oxygenase inhibitors and methods of therapeutic use |
US8283351B2 (en) | 2007-04-02 | 2012-10-09 | Institute For Oneworld Health | Cyclic and acyclic hydrazine derivatives compositions including them and uses thereof |
WO2009131957A2 (en) | 2008-04-21 | 2009-10-29 | Institute For Oneworld Health | Compounds, compositions and methods comprising oxadiazole derivatives |
WO2009131951A2 (en) | 2008-04-21 | 2009-10-29 | Institute For Oneworld Health | Compounds, compositions and methods comprising isoxazole derivatives |
US8343976B2 (en) | 2009-04-20 | 2013-01-01 | Institute For Oneworld Health | Compounds, compositions and methods comprising pyrazole derivatives |
CN102625795A (en) * | 2009-09-04 | 2012-08-01 | 分子发现***公司 | Cytotoxic compounds |
CN102127106B (en) * | 2010-12-30 | 2013-05-22 | 聊城大学 | Dichlorodiphenyl-stannane complex and preparation method and application thereof |
EP2945629A4 (en) * | 2012-11-22 | 2016-09-28 | Oncochel Therapeutics LLC | Chemotherapy for drug-resistant cancer cells |
CN105218399B (en) * | 2014-05-30 | 2018-02-09 | 中国人民解放军军事医学科学院毒物药物研究所 | A kind of substituted acethydrazide derivatives, preparation method and the usage |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4334015A (en) * | 1979-05-23 | 1982-06-08 | Minnesota Mining And Manufacturing Company | Imaging compositions |
US4277500A (en) * | 1980-03-24 | 1981-07-07 | Stauffer Chemical Company | Certain 2-hydroxy-1-naphthaldehyde acylhydrazones and their use as fungicides |
DE3372780D1 (en) * | 1982-03-09 | 1987-09-03 | Ciba Geigy Ag | Use of metal complexes of hydrazones as pigments |
AU749271B2 (en) * | 1997-07-01 | 2002-06-20 | Agouron Pharmaceuticals, Inc. | Glucagon antagonists/inverse agonists |
CA2351516A1 (en) * | 1998-11-18 | 2000-05-25 | Valery Alakhov | Copolymer compositions for treating viral infections |
AUPQ262499A0 (en) * | 1999-09-02 | 1999-09-23 | University Of Queensland, The | Novel iron chelators |
JP2003527417A (en) * | 2000-03-23 | 2003-09-16 | インフラクス,インコーポレイテッド | Bactericidal antibacterial methods and compositions for use in treating Gram-positive bacterial infections |
WO2002049413A2 (en) * | 2000-12-19 | 2002-06-27 | Smithkline Beecham Corporation | Thrombopoietin mimetics |
-
2002
- 2002-03-19 AU AUPS1209A patent/AUPS120902A0/en not_active Abandoned
-
2003
- 2003-03-19 WO PCT/AU2003/000328 patent/WO2003078386A1/en not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
WO2003078386A1 (en) | 2003-09-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
PC1 | Assignment before grant (sect. 113) |
Owner name: UNISEARCH LIMITED Free format text: THE FORMER OWNER WAS: THE HEART RESEARCH INSTITUTE LTD. |