AU8759491A - Peptides containing substituted 1,4-diamines as transition-state inserts - Google Patents

Peptides containing substituted 1,4-diamines as transition-state inserts

Info

Publication number
AU8759491A
AU8759491A AU87594/91A AU8759491A AU8759491A AU 8759491 A AU8759491 A AU 8759491A AU 87594/91 A AU87594/91 A AU 87594/91A AU 8759491 A AU8759491 A AU 8759491A AU 8759491 A AU8759491 A AU 8759491A
Authority
AU
Australia
Prior art keywords
diamines
transition
peptides containing
containing substituted
state inserts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU87594/91A
Inventor
Suvit Thaisrivongs
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AU8759491A publication Critical patent/AU8759491A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/20—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by nitrogen atoms not being part of nitro or nitroso groups
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06—Esters of carbamic acids
    • C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/22—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/26—Radicals substituted by carbon atoms having three bonds to hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/021—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -NH-(X)n-C(=0)-, n being 5 or 6; for n > 6, classification in C07K5/06 - C07K5/10, according to the moiety having normal peptide bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
AU87594/91A 1990-10-10 1991-10-01 Peptides containing substituted 1,4-diamines as transition-state inserts Abandoned AU8759491A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59547090A 1990-10-10 1990-10-10
US595740 1990-10-10

Publications (1)

Publication Number Publication Date
AU8759491A true AU8759491A (en) 1992-05-20

Family

ID=34520315

Family Applications (1)

Application Number Title Priority Date Filing Date
AU87594/91A Abandoned AU8759491A (en) 1990-10-10 1991-10-01 Peptides containing substituted 1,4-diamines as transition-state inserts

Country Status (4)

Country Link
EP (1) EP0552247A1 (en)
JP (1) JPH06502403A (en)
AU (1) AU8759491A (en)
WO (1) WO1992006996A1 (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995007269A1 (en) * 1993-09-10 1995-03-16 Narhex Limited Polar-substituted hydrocarbons
US5679688A (en) * 1992-03-11 1997-10-21 Narhex Limited Quinaldoyl-amine derivatives of oxo-and hydroxy-substituted hydrocarbons
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
US6258806B1 (en) 1992-03-11 2001-07-10 Narhex Limited Amine derivatives of oxo- and hydroxy- substituted hydrocarbons

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362912A (en) * 1989-05-23 1994-11-08 Abbott Laboratories Process for the preparation of a substituted diaminodiol
US5354866A (en) * 1989-05-23 1994-10-11 Abbott Laboratories Retroviral protease inhibiting compounds
US5539122A (en) * 1989-05-23 1996-07-23 Abbott Laboratories Retroviral protease inhibiting compounds
US5436339A (en) * 1991-03-06 1995-07-25 Abbott Laboratories Process for the preparation of a substituted diaminoalcohol
US5559256A (en) * 1992-07-20 1996-09-24 E. R. Squibb & Sons, Inc. Aminediol protease inhibitors
DK0727419T3 (en) 1992-12-29 2002-06-10 Abbott Lab Intermediates for the preparation of compounds that inhibit retroviral protease
WO1999029311A1 (en) * 1997-12-08 1999-06-17 The Scripps Research Institute Hiv/fiv protease inhibitors having a small p3 residue
FR2797689B1 (en) 1999-08-16 2003-06-27 Pasteur Sanofi Diagnostics USE OF SYNTHETIC COMPOUNDS FOR IMMUNODAYS

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988004664A2 (en) * 1986-12-22 1988-06-30 The Upjohn Company Renin-inhibitory peptides having an epoxide or glycol moiety
DE3912829A1 (en) * 1989-04-19 1990-10-25 Bayer Ag USE OF RENININHIBITIC PEPTIDES AS AGENTS AGAINST RETROVIRUS
JPH04506808A (en) * 1989-07-19 1992-11-26 ジ・アップジョン・カンパニー Peptides containing diaminoglycols as transition state mimics
EP0428849A3 (en) * 1989-09-28 1991-07-31 Hoechst Aktiengesellschaft Retroviral protease inhibitors

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5679688A (en) * 1992-03-11 1997-10-21 Narhex Limited Quinaldoyl-amine derivatives of oxo-and hydroxy-substituted hydrocarbons
US5888992A (en) * 1992-03-11 1999-03-30 Narhex Limited Polar substituted hydrocarbons
US5942504A (en) * 1992-03-11 1999-08-24 Narhex Limited Amine derivatives of oxo- and hydroxy- substituted hydrocarbons
US6071895A (en) * 1992-03-11 2000-06-06 Narhex Limited Polar-substituted hydrocarbons
US6258806B1 (en) 1992-03-11 2001-07-10 Narhex Limited Amine derivatives of oxo- and hydroxy- substituted hydrocarbons
WO1995007269A1 (en) * 1993-09-10 1995-03-16 Narhex Limited Polar-substituted hydrocarbons

Also Published As

Publication number Publication date
WO1992006996A1 (en) 1992-04-30
EP0552247A1 (en) 1993-07-28
JPH06502403A (en) 1994-03-17

Similar Documents

Publication Publication Date Title
AP9600796A0 (en) Novel insecticidal 2,4 diaminoquina-zolines
AU660321B2 (en) 1,2-dihydro-2-oxopyridine
AU8031191A (en) Package
AU7636794A (en) Compositions including 1,1,1,2,3,4,4,5,5,5-decafluoropentane
AU8740991A (en) Peptides containing amino-polyols as transition-state mimics
AU8554691A (en) Improved formulations
AU2868789A (en) 1,4-disubstituted-piperidinyl compounds
AU8557191A (en) Multiple bag
AU8553891A (en) 1-(2-arylethyl)-pyrrolidines
GR3030863T3 (en) 2',5'-oligoadenylate-2',3'-cyclophosphates
AU8043491A (en) Fungicides
AU8759491A (en) Peptides containing substituted 1,4-diamines as transition-state inserts
AU4717089A (en) N-(3,4-Dioxy-and N-(4-oxy-3-thio-benzyl)-thioureas
AU9030991A (en) Improved capacitor-sensor
AU7055991A (en) Shoes
AU8126191A (en) Novel herbicides
AU7805191A (en) Improved knifegate valve
AU1633995A (en) 1,4-diamino-2,3-dihydroxybutanes
AU9171791A (en) N-protected aminoalkylaldehydes
AU3384793A (en) 2-acetyl-3-keto-4,5-dihydrothiphene compounds
AU8043891A (en) Fungicides
AU4718989A (en) 4-amino-5-nitro-1,2,3,6-tetrahydropyrimidines
AU8516291A (en) Instant photograph-postcard
AU7686394A (en) Rectally-administered, epileptic-seizure-inhibiting composition
AU7709991A (en) Phenoxyphenylsulphonyl compounds