AU8162898A - Angiogenic modulation by notch signal transduction - Google Patents

Angiogenic modulation by notch signal transduction

Info

Publication number
AU8162898A
AU8162898A AU81628/98A AU8162898A AU8162898A AU 8162898 A AU8162898 A AU 8162898A AU 81628/98 A AU81628/98 A AU 81628/98A AU 8162898 A AU8162898 A AU 8162898A AU 8162898 A AU8162898 A AU 8162898A
Authority
AU
Australia
Prior art keywords
signal transduction
notch signal
angiogenic
modulation
angiogenic modulation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU81628/98A
Inventor
Jan Kitajewski
Hendrik Uyttendaele
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Columbia University in the City of New York
Original Assignee
Columbia University in the City of New York
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Columbia University in the City of New York filed Critical Columbia University in the City of New York
Publication of AU8162898A publication Critical patent/AU8162898A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
AU81628/98A 1997-06-18 1998-06-18 Angiogenic modulation by notch signal transduction Abandoned AU8162898A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US87835197A 1997-06-18 1997-06-18
US08878351 1997-06-18
PCT/US1998/013050 WO1998057621A1 (en) 1997-06-18 1998-06-18 Angiogenic modulation by notch signal transduction

Publications (1)

Publication Number Publication Date
AU8162898A true AU8162898A (en) 1999-01-04

Family

ID=25371857

Family Applications (1)

Application Number Title Priority Date Filing Date
AU81628/98A Abandoned AU8162898A (en) 1997-06-18 1998-06-18 Angiogenic modulation by notch signal transduction

Country Status (2)

Country Link
AU (1) AU8162898A (en)
WO (1) WO1998057621A1 (en)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9912132D0 (en) * 1999-05-26 1999-07-28 Univ Manchester Notch regulator-related gene and uses thereof
GB0013212D0 (en) * 2000-05-31 2000-07-19 Schizophrenia Ass Of Great Bri Notch 4 and schizophrenia
AU2008200135B2 (en) * 2000-08-03 2012-06-14 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
US6984522B2 (en) 2000-08-03 2006-01-10 Regents Of The University Of Michigan Isolation and use of solid tumor stem cells
JP2005511754A (en) * 2001-12-07 2005-04-28 リージェンツ オブ ザ ユニバーシティ オブ ミシガン Predictive identification and characterization of breast cancer stem cells
US20040077569A1 (en) * 2002-10-16 2004-04-22 Isis Pharmaceuticals Inc. Antisense modulation of Notch (Drosophila) homolog 4 expression
WO2006085224A2 (en) * 2005-02-07 2006-08-17 Karolinska Innovations Ab Modulation of cellular hypoxia responses through notch signalling
CA2628221A1 (en) 2005-10-31 2007-05-10 Oncomed Pharmaceuticals, Inc. Anti-frizzled receptor antibodies for treating cancer
US7723477B2 (en) 2005-10-31 2010-05-25 Oncomed Pharmaceuticals, Inc. Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
PL2032166T3 (en) 2006-06-13 2013-09-30 Oncomed Pharm Inc Compositions and methods for diagnosing and treating cancer
JP5535633B2 (en) 2006-09-29 2014-07-02 オンコメッド ファーマシューティカルズ インコーポレイテッド Compositions and methods for diagnosis and treatment of cancer
WO2008091641A2 (en) 2007-01-24 2008-07-31 Oncomed Pharmaceuticals, Inc. Compositions and methods for diagnosing and treating cancer
JP2010520280A (en) * 2007-03-05 2010-06-10 ボード オブ リージェンツ， ザ ユニバーシティ オブ テキサス システム Negative genetic control of cancer cell regeneration with synergy with Notch or Num specific immunotherapy
US9132189B2 (en) 2008-07-08 2015-09-15 Oncomed Pharmaceuticals, Inc. Notch1 binding agents and methods of use thereof
PL2307459T3 (en) 2008-07-08 2015-05-29 Oncomed Pharm Inc Notch1 receptor binding agents and methods of use thereof
PT2331136T (en) 2008-09-26 2018-03-27 Oncomed Pharm Inc Frizzled-binding agents and uses thereof
JP2010214019A (en) * 2009-03-18 2010-09-30 Chiba Univ Ischemic tissue regeneration method using notch signal
PT2488204E (en) 2009-10-16 2016-06-09 Oncomed Pharm Inc Therapeutic combination and use of dll4 antagonist antibodies and anti-hypertensive agents
TWI535445B (en) 2010-01-12 2016-06-01 安可美德藥物股份有限公司 Wnt antagonists and methods of treatment and screening
ES2561102T3 (en) 2010-01-13 2016-02-24 Oncomed Pharmaceuticals, Inc. Binding agents to Notch1 and procedures for their use
JP2013530929A (en) 2010-04-01 2013-08-01 オンコメッド ファーマシューティカルズ インコーポレイテッド Frizzled binders and uses thereof
US8551479B2 (en) 2010-09-10 2013-10-08 Oncomed Pharmaceuticals, Inc. Methods for treating melanoma
LT2758073T (en) 2011-09-23 2019-01-10 Oncomed Pharmaceuticals, Inc. Vegf/dll4 binding agents and uses thereof
US9266959B2 (en) 2012-10-23 2016-02-23 Oncomed Pharmaceuticals, Inc. Methods of treating neuroendocrine tumors using frizzled-binding agents
US20140227252A1 (en) 2012-10-31 2014-08-14 Oncomed Pharmaceuticals , Inc. Methods and Monitoring of Treatment with a DLL4 Antagonist
AU2014212081A1 (en) 2013-02-04 2015-08-13 Oncomed Pharmaceuticals, Inc. Methods and monitoring of treatment with a Wnt pathway inhibitor
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
MX2017005258A (en) 2014-10-31 2017-07-26 Oncomed Pharm Inc Combination therapy for treatment of disease.
CN109071644B (en) 2015-09-23 2023-09-19 昂考梅德药品有限公司 Methods and compositions for treating cancer
WO2024074649A1 (en) * 2022-10-05 2024-04-11 Alcea Therapeutics, Inc. Notch4 antibodies, compositions, and methods for treating airway inflammation

Also Published As

Publication number Publication date
WO1998057621A1 (en) 1998-12-23

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase