AU7803500A - Process for the preparation of phosphorothioate triesters and oligonucleotides - Google Patents
Process for the preparation of phosphorothioate triesters and oligonucleotidesInfo
- Publication number
- AU7803500A AU7803500A AU78035/00A AU7803500A AU7803500A AU 7803500 A AU7803500 A AU 7803500A AU 78035/00 A AU78035/00 A AU 78035/00A AU 7803500 A AU7803500 A AU 7803500A AU 7803500 A AU7803500 A AU 7803500A
- Authority
- AU
- Australia
- Prior art keywords
- oligonucleotides
- preparation
- phosphorothioate triesters
- triesters
- phosphorothioate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H1/00—Processes for the preparation of sugar derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9924285.1A GB9924285D0 (en) | 1999-10-14 | 1999-10-14 | Process |
| GB9924285 | 1999-10-14 | ||
| PCT/GB2000/003912 WO2001027126A1 (en) | 1999-10-14 | 2000-10-12 | Process for the preparation of phosphorothioate triesters and oligonucleotides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU7803500A true AU7803500A (en) | 2001-04-23 |
Family
ID=10862710
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU78035/00A Abandoned AU7803500A (en) | 1999-10-14 | 2000-10-12 | Process for the preparation of phosphorothioate triesters and oligonucleotides |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1224193A1 (en) |
| JP (1) | JP2003517467A (en) |
| CN (1) | CN1409719A (en) |
| AU (1) | AU7803500A (en) |
| CA (1) | CA2386867A1 (en) |
| GB (1) | GB9924285D0 (en) |
| WO (1) | WO2001027126A1 (en) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0004889D0 (en) | 2000-03-01 | 2000-04-19 | Avecia Ltd | Synthesis of oligonucleotides |
| EP2332954A3 (en) * | 2000-12-05 | 2011-12-21 | Avecia Biotechnology, Inc. | Process for the preparation of phosphorothionate oligonucleotides |
| GB0229423D0 (en) * | 2002-12-18 | 2003-01-22 | Avecia Ltd | Process |
| CN101684136A (en) * | 2008-09-23 | 2010-03-31 | 苏州瑞博生物技术有限公司 | Method for preparing oligonucleotides |
| CA2744987C (en) | 2008-12-02 | 2018-01-16 | Chiralgen, Ltd. | Method for the synthesis of phosphorus atom modified nucleic acids |
| BR112012000828A8 (en) | 2009-07-06 | 2017-10-10 | Ontorii Inc | NEW NUCLEIC ACID PRO-DRUGS AND METHODS OF THEIR USE |
| WO2012039448A1 (en) | 2010-09-24 | 2012-03-29 | 株式会社キラルジェン | Asymmetric auxiliary group |
| US9605019B2 (en) | 2011-07-19 | 2017-03-28 | Wave Life Sciences Ltd. | Methods for the synthesis of functionalized nucleic acids |
| AU2013288048A1 (en) | 2012-07-13 | 2015-01-22 | Wave Life Sciences Ltd. | Asymmetric auxiliary group |
| KR20220139425A (en) | 2012-07-13 | 2022-10-14 | 웨이브 라이프 사이언시스 리미티드 | Chiral control |
| KR101835401B1 (en) | 2012-07-13 | 2018-03-08 | 신 니뽄 바이오메디칼 라보라토리즈, 엘티디. | Chiral nucleic acid adjuvant |
| WO2015108048A1 (en) | 2014-01-15 | 2015-07-23 | 株式会社新日本科学 | Chiral nucleic acid adjuvant having antitumor effect and antitumor agent |
| US10322173B2 (en) | 2014-01-15 | 2019-06-18 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having anti-allergic activity, and anti-allergic agent |
| EP3095461A4 (en) | 2014-01-15 | 2017-08-23 | Shin Nippon Biomedical Laboratories, Ltd. | Chiral nucleic acid adjuvant having immunity induction activity, and immunity induction activator |
| PT3094728T (en) | 2014-01-16 | 2022-05-19 | Wave Life Sciences Ltd | Chiral design |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2976436B2 (en) * | 1988-04-27 | 1999-11-10 | 味の素株式会社 | Novel oligoribonucleotide derivatives and use as antiviral agents |
| GB9717158D0 (en) * | 1997-08-13 | 1997-10-22 | King S College London | Solution synthesis of oligonucleotides and their phosphorothioate analogues |
-
1999
- 1999-10-14 GB GBGB9924285.1A patent/GB9924285D0/en not_active Ceased
-
2000
- 2000-10-12 JP JP2001530344A patent/JP2003517467A/en active Pending
- 2000-10-12 CA CA002386867A patent/CA2386867A1/en not_active Abandoned
- 2000-10-12 AU AU78035/00A patent/AU7803500A/en not_active Abandoned
- 2000-10-12 CN CN 00816977 patent/CN1409719A/en active Pending
- 2000-10-12 EP EP00968075A patent/EP1224193A1/en not_active Withdrawn
- 2000-10-12 WO PCT/GB2000/003912 patent/WO2001027126A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| JP2003517467A (en) | 2003-05-27 |
| CN1409719A (en) | 2003-04-09 |
| GB9924285D0 (en) | 1999-12-15 |
| CA2386867A1 (en) | 2001-04-19 |
| WO2001027126A1 (en) | 2001-04-19 |
| EP1224193A1 (en) | 2002-07-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MK6 | Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase |