AU7683196A - Peptide conjugates, use thereof as a drug, and compositions containing same - Google Patents

Peptide conjugates, use thereof as a drug, and compositions containing same

Info

Publication number
AU7683196A
AU7683196A AU76831/96A AU7683196A AU7683196A AU 7683196 A AU7683196 A AU 7683196A AU 76831/96 A AU76831/96 A AU 76831/96A AU 7683196 A AU7683196 A AU 7683196A AU 7683196 A AU7683196 A AU 7683196A
Authority
AU
Australia
Prior art keywords
lys
lysine
drug
compositions containing
conjugates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU76831/96A
Inventor
Lucien Dussourd D'hinterland
Anne-Marie Pinel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Europeen de Biologie Cellulaire
Original Assignee
RECH DE PATHOLOGIE APPLIQUEE S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RECH DE PATHOLOGIE APPLIQUEE S filed Critical RECH DE PATHOLOGIE APPLIQUEE S
Publication of AU7683196A publication Critical patent/AU7683196A/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/4986Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with sulfur as the only hetero atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/36Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/64Proteins; Peptides; Derivatives or degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • A61Q19/08Anti-ageing preparations
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0819Tripeptides with the first amino acid being acidic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10Tetrapeptides
    • C07K5/1019Tetrapeptides with the first amino acid being basic
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/57Compounds covalently linked to a(n inert) carrier molecule, e.g. conjugates, pro-fragrances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Abstract

Peptide conjugates including a sequence of at least three amino acids selected from Lys-Lys-Gly, Gly-His-Lys and Glu-His-Lys, wherein "Lys" is Lysine or a halogenated derivative thereof, or a methylated Lysine derivative, particularly Methyl-Lysine and Dihydrobromo-Methyl-Lysine, said amino acids optionally being in D, L or DL form, and said sequence being chemically or physically conjugated with at least one compound selected from monocarboxylic acids of general formula (I): HOOC-R, or alcohol, aldehyde or amide derivatives thereof, and dicarboxylic acids of general formula (II): HOOC-R1-COOH, are disclosed. The use of such conjugates as a drug, and pharmaceutical or cosmetic compositions containing said conjugates, are also disclosed.
AU76831/96A 1995-11-15 1996-11-15 Peptide conjugates, use thereof as a drug, and compositions containing same Abandoned AU7683196A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9513543A FR2741075B1 (en) 1995-11-15 1995-11-15 PEPTIDE CONJUGATES, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM
FR9513543 1995-11-15
PCT/FR1996/001811 WO1997018235A1 (en) 1995-11-15 1996-11-15 Peptide conjugates, use thereof as a drug, and compositions containing same

Publications (1)

Publication Number Publication Date
AU7683196A true AU7683196A (en) 1997-06-05

Family

ID=9484595

Family Applications (1)

Application Number Title Priority Date Filing Date
AU76831/96A Abandoned AU7683196A (en) 1995-11-15 1996-11-15 Peptide conjugates, use thereof as a drug, and compositions containing same

Country Status (9)

Country Link
EP (1) EP0869969B1 (en)
JP (1) JP2000512613A (en)
AT (1) ATE235508T1 (en)
AU (1) AU7683196A (en)
CA (1) CA2237993A1 (en)
DE (1) DE69627019T2 (en)
ES (1) ES2193272T3 (en)
FR (1) FR2741075B1 (en)
WO (1) WO1997018235A1 (en)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7001992B2 (en) 1997-05-30 2006-02-21 Human Genome Sciences, Inc. Antibodies to secreted protein HEMCM42
EP1015477B1 (en) * 1997-05-30 2010-11-10 Human Genome Sciences, Inc. 32 Human secreted proteins
FR2802413B1 (en) * 1999-12-17 2003-10-31 Sederma Sa COSMETIC OR DERMOPHARMACEUTICAL COMPOSITIONS CONTAINING THE N-PALMYTOYL-GLY-HYS-LYS TRIPEPTIDE FOR ELIMINATING, REDUCING OR PREVENTING THE APPEARANCE OF WRINKLES, WHEREVER THE LOCATION AND THE CAUSE
FR2810323B1 (en) * 2000-06-16 2002-09-06 Shiseido Int France COSMETIC USE OF A LIPOPEPTIDE
KR100753472B1 (en) * 2002-03-15 2007-08-31 주식회사 엘지생활건강 Fusion peptide comprising tat peptide and human type-? collagen derived peptide, its preparation method, and anti-aging cosmetic composition comprising the same
FR2857667B1 (en) 2003-07-18 2007-07-13 Inst Europ Biolog Cellulaire NEW PEPTIDE CONJUGATES USEFUL IN THE PREVENTIVE AND CURATIVE TREATMENT OF ALOPECIA
FR2857597B1 (en) 2003-07-18 2008-01-25 Inst Europeen Biolog Cellulair USE OF PEPTIDE CONJUGATES FOR THE PREPARATION OF COMPOSITIONS FOR THE PREVENTIVE AND CURATIVE TREATMENT OF ALOPECIA.
EP1737819B1 (en) 2004-03-26 2010-12-22 DSM IP Assets B.V. Amino acid and peptide conjugates of arylalkylic acids for cosmetic use
FR2870244B1 (en) * 2004-05-11 2011-01-07 Centre Nat Rech Scient ALPHA-MSH ANTAGONIST DIPEPTIDE CONJUGATES
FR2913603A1 (en) * 2007-03-15 2008-09-19 Michel Yvan Hocquaux COSMETIC COMPOSITION FOR SKIN CARE AGREED BY AESTHETIC TREATMENT SUCH AS SURGICAL INTERVENTION, LASER TREATMENT, DERMABRASION, PEELING CAT.INIST logo CNRS logo INIST Accueil / Home Imprimer / Print Contact / Contact PARTAGER / SHARE EXPORT Bookmark and Share Mendeley.
US20100310484A1 (en) * 2007-06-29 2010-12-09 Innovactiv Inc. Novel peptides, use thereof in cosmetic and cosmeceutic applications, and compositions comprising same
ES2605162T3 (en) * 2007-06-29 2017-03-13 Lucas Meyer Cosmetics Canada Inc. New compounds, use thereof in cosmetic and cosmo pharmaceutical applications, and compositions comprising them
PT2165698E (en) 2008-09-18 2016-06-23 Universkin Cosmetic composition designed to protect damaged skin
US7928067B2 (en) 2009-05-14 2011-04-19 Ischemix Llc Compositions and methods for treating ischemia and ischemia-reperfusion injury
DE102009055970B4 (en) * 2009-11-27 2014-04-17 Marcus Asam Cosmetic preparation of active ingredient
KR20140020840A (en) 2010-11-18 2014-02-19 이쉐믹스 엘엘씨 Lipoyl compounds and their use for treating ischemic injury
FR2986528B1 (en) * 2012-02-06 2015-12-04 Inst Europeen Biolog Cellulair NEW ANTI-AGING PEPTIDES
EP3615023B1 (en) 2017-04-25 2023-06-21 Ischemix LLC Lipoyl-glu-ala for the treatment of neurodegenerative damage caused by traumatic brain injury

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5120831A (en) * 1985-02-08 1992-06-09 Procyte Corporation Metal-peptide compositions
US5118665A (en) * 1990-02-09 1992-06-02 Procyte Corporation Anti-oxidative and anti-inflammatory metal:peptide complexes and uses thereof
DE4127790A1 (en) * 1991-08-22 1993-02-25 Wank Anna New oligopeptide(s) and metal complexes - used in skin-care cosmetics

Also Published As

Publication number Publication date
ES2193272T3 (en) 2003-11-01
CA2237993A1 (en) 1997-05-22
WO1997018235A1 (en) 1997-05-22
EP0869969A1 (en) 1998-10-14
FR2741075A1 (en) 1997-05-16
JP2000512613A (en) 2000-09-26
EP0869969B1 (en) 2003-03-26
DE69627019T2 (en) 2004-01-22
FR2741075B1 (en) 1998-01-30
DE69627019D1 (en) 2003-04-30
ATE235508T1 (en) 2003-04-15

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