AU7257994A - Novel protein inhibitors of serine proteinases (e.g. furin) derived from turkey ovomucoid third domain - Google Patents

Novel protein inhibitors of serine proteinases (e.g. furin) derived from turkey ovomucoid third domain

Info

Publication number
AU7257994A
AU7257994A AU72579/94A AU7257994A AU7257994A AU 7257994 A AU7257994 A AU 7257994A AU 72579/94 A AU72579/94 A AU 72579/94A AU 7257994 A AU7257994 A AU 7257994A AU 7257994 A AU7257994 A AU 7257994A
Authority
AU
Australia
Prior art keywords
furin
domain
derived
novel protein
protein inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU72579/94A
Inventor
Stephen Anderson
Michael Laskowski
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU7257994A publication Critical patent/AU7257994A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6454Dibasic site splicing serine proteases, e.g. kexin (3.4.21.61); furin (3.4.21.75) and other proprotein convertases
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/81Protease inhibitors
    • C07K14/8107Endopeptidase (E.C. 3.4.21-99) inhibitors
    • C07K14/811Serine protease (E.C. 3.4.21) inhibitors
    • C07K14/8135Kazal type inhibitors, e.g. pancreatic secretory inhibitor, ovomucoid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
AU72579/94A 1993-07-09 1994-07-08 Novel protein inhibitors of serine proteinases (e.g. furin) derived from turkey ovomucoid third domain Abandoned AU7257994A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US8924893A 1993-07-09 1993-07-09
US089248 1993-07-09
PCT/US1994/007779 WO1995002055A1 (en) 1993-07-09 1994-07-08 Novel protein inhibitors of serine proteinases (e.g. furin) derived from turkey ovomucoid third domain

Publications (1)

Publication Number Publication Date
AU7257994A true AU7257994A (en) 1995-02-06

Family

ID=22216550

Family Applications (1)

Application Number Title Priority Date Filing Date
AU72579/94A Abandoned AU7257994A (en) 1993-07-09 1994-07-08 Novel protein inhibitors of serine proteinases (e.g. furin) derived from turkey ovomucoid third domain

Country Status (2)

Country Link
AU (1) AU7257994A (en)
WO (1) WO1995002055A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2266323A1 (en) 1996-09-24 1998-04-02 The Procter & Gamble Company Stabilized proteinaceous protease inhibitors and variants thereof
WO1999033974A1 (en) * 1997-12-23 1999-07-08 Forssmann Wolf Georg Serine proteinase inhibitors
EP1475435A1 (en) * 2003-05-09 2004-11-10 Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. Prohormone/proprotein-proteinase crystal structure and use thereof
CN1908010B (en) * 2005-08-05 2012-02-29 同济大学 Furin enzyme inhibitor of resisting HIV-1 and preparation method thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2599752B1 (en) * 1986-06-10 1989-11-03 Transgene Sa ALPHA1- ANTITRYPSIN VARIANTS USEFUL IN PARTICULAR AS KALLIKREIN INHIBITORS

Also Published As

Publication number Publication date
WO1995002055A1 (en) 1995-01-19

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