AU7216996A - A paf-acetylhydrolase and use in therapy - Google Patents
A paf-acetylhydrolase and use in therapyInfo
- Publication number
- AU7216996A AU7216996A AU72169/96A AU7216996A AU7216996A AU 7216996 A AU7216996 A AU 7216996A AU 72169/96 A AU72169/96 A AU 72169/96A AU 7216996 A AU7216996 A AU 7216996A AU 7216996 A AU7216996 A AU 7216996A
- Authority
- AU
- Australia
- Prior art keywords
- acetylhydrolase
- paf
- therapy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Pulmonology (AREA)
- Diabetes (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Rheumatology (AREA)
- Cardiology (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Pain & Pain Management (AREA)
- Microbiology (AREA)
- Urology & Nephrology (AREA)
- Immunology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
WO502320 | 1995-09-29 | ||
PCT/GB1995/002320 WO1997012984A1 (en) | 1995-09-29 | 1995-09-29 | COMPOUND HAVING SEQUENCE HOMOLOGY WITH LIPOPROTEIN ASSOCIATED PHOSPHOLIPASE A2 (Lp-PLA2)/PAF ACETYL HYDROLASE |
GB9617781 | 1996-08-24 | ||
GBGB9617781.1A GB9617781D0 (en) | 1996-08-24 | 1996-08-24 | New use |
PCT/EP1996/004268 WO1997012963A2 (en) | 1995-09-29 | 1996-09-26 | A paf-acetylhydrolase and use in therapy |
Publications (1)
Publication Number | Publication Date |
---|---|
AU7216996A true AU7216996A (en) | 1997-04-28 |
Family
ID=26306449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU72169/96A Abandoned AU7216996A (en) | 1995-09-29 | 1996-09-26 | A paf-acetylhydrolase and use in therapy |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0859834A2 (en) |
JP (1) | JP2002515728A (en) |
AU (1) | AU7216996A (en) |
CA (1) | CA2233300A1 (en) |
WO (1) | WO1997012963A2 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999009147A1 (en) * | 1997-08-13 | 1999-02-25 | Icos Corporation | Truncated platelet-activating factor acetylhydrolase |
AU2001235466B2 (en) | 2000-02-16 | 2004-04-22 | Glaxo Group Limited | Pyrimidine-4-one derivatives as LDL-PLA2 inhibitors |
EP2649053B1 (en) | 2010-12-06 | 2015-11-04 | Glaxo Group Limited | Pyrimidinone compounds for use in the treatment of diseases or conditions mediated by lp-pla2 |
US20130267544A1 (en) | 2010-12-17 | 2013-10-10 | Peter Adamson | Use of LP-PLA2 Inhibitors in the Treatment and Prevention of Eye Diseases |
US9273054B2 (en) | 2011-07-27 | 2016-03-01 | Glaxo Group Limited | Substituted pyrimido[1,6-a]pyrimidines as Lp-PLA2 inhibitors |
EP2739627A4 (en) | 2011-07-27 | 2015-01-21 | Glaxo Group Ltd | 2,3-dihydroimidazo[1,2-c]pyrimidin-5(1h)-one compounds use as lp-pla² inhibitors |
RU2015135806A (en) | 2013-01-25 | 2017-03-03 | Глэксосмитклайн Интеллекчуал Проперти Дивелопмент Лимитед | COMPOUNDS |
UY35276A (en) | 2013-01-25 | 2014-08-29 | Glaxosmithkline Ip Dev Ltd | New compounds that inhibit the activity of Lp-PLA2 |
KR20150108896A (en) | 2013-01-25 | 2015-09-30 | 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 | Bicyclic pyrimidone compounds as inhibitors of lp-pla2 |
WO2016012916A1 (en) | 2014-07-22 | 2016-01-28 | Glaxosmithkline Intellectual Property Development Limited | 1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidine derivatives useful in the treatment of diseases and disorders mediated by lp-pla2 |
WO2016012917A1 (en) | 2014-07-22 | 2016-01-28 | Glaxosmithkline Intellectual Property Development Limited | 1,2,3,5-tetrahydroimidazo[1,2-c]pyrimidine derivatives useful in the treatment of diseases and disorders mediated by lp-pla2 |
PE20230092A1 (en) | 2019-11-09 | 2023-01-16 | Shanghai Simr Biotechnology Co Ltd | DIHYDROIMIDAZOPYRIMIDONE TRICYCLIC DERIVATIVE, METHOD OF PREPARATION THEREOF, PHARMACEUTICAL COMPOSITION AND USE THEREOF |
CN115304620A (en) | 2021-05-07 | 2022-11-08 | 上海赛默罗生物科技有限公司 | Pyrimidone derivatives, preparation method, pharmaceutical composition and application thereof |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5981252A (en) * | 1993-06-25 | 1999-11-09 | Smithkline Beecham | Lipoprotein associated phospholipase A2, inhibitors thereof and use of the same in diagnosis and therapy |
PT673426E (en) * | 1993-10-06 | 2001-11-30 | Icos Corp | ACETYL HYDROLASE OF THE ACTIVATING FACTOR OF PLATELETS |
-
1996
- 1996-09-26 JP JP51396697A patent/JP2002515728A/en active Pending
- 1996-09-26 WO PCT/EP1996/004268 patent/WO1997012963A2/en not_active Application Discontinuation
- 1996-09-26 CA CA002233300A patent/CA2233300A1/en not_active Abandoned
- 1996-09-26 EP EP96933431A patent/EP0859834A2/en not_active Withdrawn
- 1996-09-26 AU AU72169/96A patent/AU7216996A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1997012963A2 (en) | 1997-04-10 |
CA2233300A1 (en) | 1997-04-10 |
EP0859834A2 (en) | 1998-08-26 |
JP2002515728A (en) | 2002-05-28 |
WO1997012963A3 (en) | 1997-06-12 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
AU703128B2 (en) | Device in inhalers | |
AU5772196A (en) | 3,4-disubstituted-phenylsulphonamides and their therapeutic use | |
SG44943A1 (en) | Metallocene preparation and use | |
AU7230196A (en) | Pskh-1 ribozymes and uses in disease treatment | |
AU6200196A (en) | Device and algorithm for a combined cardiomyostimulator and a cardiac pacer-cardioverter-defibrillator | |
AU1372897A (en) | 2-amino-heterocycles and therapeutic uses therefor | |
AU5772296A (en) | 3,4-disubstituted-phenylsulphonamides and their therapeutic use | |
IL118442A0 (en) | Triazolymethyl-cyclopentanols their preparation and use | |
AU5772396A (en) | 3,4-disubstituted-phenylsulphonamides and their therapeutic use | |
GB2304309B (en) | Laminate and use thereof | |
IL118441A0 (en) | Triazolymethyl-oxiranes their preparation and use | |
AU7216996A (en) | A paf-acetylhydrolase and use in therapy | |
EP0836617A4 (en) | Parevins and tachytegrins | |
AU3634595A (en) | Bis-oxazolidines and their use | |
AU7529796A (en) | S-nitroso-hemoglobin and therapeutic uses thereof | |
AU2512495A (en) | Therapeutic phenoxyalkylazoles and phenoxyalkylazines | |
EP0744125A3 (en) | Iodo-complex and its use | |
AU5188296A (en) | Carbopeptoids and carbonucleotoids | |
IL118444A0 (en) | Mercapto-triazolyl-silanes their preparation and use | |
IL122686A0 (en) | Benzylhydroxylamines their preparation and use | |
AU5697996A (en) | Peptidyl compounds and their therapeutic use | |
AU5975094A (en) | 1,2,4-triazinone derivatives and their use in therapy | |
AU7078094A (en) | Allatostatins and their use | |
GB9625041D0 (en) | Improvements in and relating surfaces | |
AU3776495A (en) | Aryloxycycloalkenyl and aryloxyiminocycloalkenylhydroxyureas |