AU694278B2 - Osteoporosis remedy and triazepine compound - Google Patents

Osteoporosis remedy and triazepine compound

Info

Publication number
AU694278B2
AU694278B2 AU38807/95A AU3880795A AU694278B2 AU 694278 B2 AU694278 B2 AU 694278B2 AU 38807/95 A AU38807/95 A AU 38807/95A AU 3880795 A AU3880795 A AU 3880795A AU 694278 B2 AU694278 B2 AU 694278B2
Authority
AU
Australia
Prior art keywords
triazepine compound
osteoporosis remedy
osteoporosis
remedy
triazepine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU38807/95A
Other versions
AU3880795A (en
Inventor
Yoshihisa Koga
Takeshi Nakamura
Masanori Shindo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japan Tobacco Inc
Original Assignee
Japan Tobacco Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Japan Tobacco Inc filed Critical Japan Tobacco Inc
Publication of AU3880795A publication Critical patent/AU3880795A/en
Application granted granted Critical
Publication of AU694278B2 publication Critical patent/AU694278B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D255/00Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00
    • C07D255/04Heterocyclic compounds containing rings having three nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D249/00 - C07D253/00 condensed with carbocyclic rings or ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU38807/95A 1994-11-18 1995-11-15 Osteoporosis remedy and triazepine compound Ceased AU694278B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP30994294 1994-11-18
JP6-309942 1994-11-18
PCT/JP1995/002338 WO1996016062A1 (en) 1994-11-18 1995-11-15 Osteoporosis remedy and triazepine compound

Publications (2)

Publication Number Publication Date
AU3880795A AU3880795A (en) 1996-06-17
AU694278B2 true AU694278B2 (en) 1998-07-16

Family

ID=17999209

Family Applications (1)

Application Number Title Priority Date Filing Date
AU38807/95A Ceased AU694278B2 (en) 1994-11-18 1995-11-15 Osteoporosis remedy and triazepine compound

Country Status (7)

Country Link
US (1) US5807850A (en)
EP (1) EP0792880A4 (en)
CN (1) CN1171788A (en)
AU (1) AU694278B2 (en)
CA (1) CA2205173A1 (en)
HU (1) HUT77349A (en)
WO (1) WO1996016062A1 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL330635A1 (en) * 1996-06-12 1999-05-24 Japan Tobacco Inc Inhibitor of cytokin production, triazepin compound and intermediate compounds used for obtaining the last mentioned one
US7879840B2 (en) 2005-08-25 2011-02-01 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US8022058B2 (en) 2000-05-10 2011-09-20 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US7393652B2 (en) 2000-05-10 2008-07-01 The Trustees Of Columbia University In The City Of New York Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2)
US7718644B2 (en) 2004-01-22 2010-05-18 The Trustees Of Columbia University In The City Of New York Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof
US7544678B2 (en) 2002-11-05 2009-06-09 The Trustees Of Columbia University In The City Of New York Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2)
JP2007525165A (en) 2003-03-07 2007-09-06 トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク Type 1 ryanodine receptor based method
US8710045B2 (en) 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
US7704990B2 (en) 2005-08-25 2010-04-27 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
EP3050885B1 (en) * 2009-11-05 2017-10-18 GlaxoSmithKline LLC Benzodiazepine bromodomain inhibitor
WO2011161031A1 (en) 2010-06-22 2011-12-29 Glaxosmithkline Llc Benzotriazolodiazepine compounds inhibitors of bromodomains
WO2018221679A1 (en) * 2017-05-31 2018-12-06 あゆみ製薬株式会社 6h-thieno[2,3-e][1,2,4]triazolo[3,4-c][1,2,4]triazepine derivative
JP2021527136A (en) 2018-06-13 2021-10-11 ディブリー・アーゲー Preparation of condensed triazepine derivatives and their use as BET inhibitors

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3891666A (en) * 1973-08-27 1975-06-24 Upjohn Co 6-Phenyl-s-triazolo{8 4,3-a{9 {8 1,3,4{9 -benzotriazepines and their preparation
US4144233A (en) * 1977-02-16 1979-03-13 The Dow Chemical Company Method for preparing benzo-(1,3,4)-benzotriazepines
US4094871A (en) * 1977-02-16 1978-06-13 The Dow Chemical Company 1,3,4-Benzotriazepine-2-thiones
US4455307A (en) * 1982-01-04 1984-06-19 The Upjohn Company Antihypertensive use of triazolobenzodiazepines
JP3239364B2 (en) * 1991-10-11 2001-12-17 ウェルファイド株式会社 Osteoporosis drug and diazepine compound

Also Published As

Publication number Publication date
AU3880795A (en) 1996-06-17
EP0792880A1 (en) 1997-09-03
EP0792880A4 (en) 1998-03-25
HUT77349A (en) 1998-03-30
CN1171788A (en) 1998-01-28
CA2205173A1 (en) 1996-05-30
US5807850A (en) 1998-09-15
WO1996016062A1 (en) 1996-05-30

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Legal Events

Date Code Title Description
MK14 Patent ceased section 143(a) (annual fees not paid) or expired