AU6887698A - Study and treatment of diseases related to specific cellular functions of receptor protein tyrosine kinases - Google Patents
Study and treatment of diseases related to specific cellular functions of receptor protein tyrosine kinasesInfo
- Publication number
- AU6887698A AU6887698A AU68876/98A AU6887698A AU6887698A AU 6887698 A AU6887698 A AU 6887698A AU 68876/98 A AU68876/98 A AU 68876/98A AU 6887698 A AU6887698 A AU 6887698A AU 6887698 A AU6887698 A AU 6887698A
- Authority
- AU
- Australia
- Prior art keywords
- study
- treatment
- receptor protein
- tyrosine kinases
- protein tyrosine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/566—Immunoassay; Biospecific binding assay; Materials therefor using specific carrier or receptor proteins as ligand binding reagents where possible specific carrier or receptor proteins are classified with their target compounds
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
- G01N2333/90—Enzymes; Proenzymes
- G01N2333/91—Transferases (2.)
- G01N2333/912—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
- G01N2333/91205—Phosphotransferases in general
- G01N2333/9121—Phosphotransferases in general with an alcohol group as acceptor (2.7.1), e.g. general tyrosine, serine or threonine kinases
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US4320797P | 1997-04-08 | 1997-04-08 | |
| US60043207 | 1997-04-08 | ||
| US5171597P | 1997-07-03 | 1997-07-03 | |
| US60051715 | 1997-07-03 | ||
| PCT/US1998/006842 WO1998045708A1 (en) | 1997-04-08 | 1998-04-07 | Study and treatment of diseases related to specific cellular functions of receptor protein tyrosine kinases |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU6887698A true AU6887698A (en) | 1998-10-30 |
Family
ID=26720144
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU68876/98A Abandoned AU6887698A (en) | 1997-04-08 | 1998-04-07 | Study and treatment of diseases related to specific cellular functions of receptor protein tyrosine kinases |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU6887698A (en) |
| WO (1) | WO1998045708A1 (en) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6316635B1 (en) | 1995-06-07 | 2001-11-13 | Sugen, Inc. | 2-indolinone derivatives as modulators of protein kinase activity |
| US6147106A (en) | 1997-08-20 | 2000-11-14 | Sugen, Inc. | Indolinone combinatorial libraries and related products and methods for the treatment of disease |
| US6677135B1 (en) | 1996-05-08 | 2004-01-13 | Biogen, Inc. | Ret ligand (RetL) for stimulating neutral and renal growth |
| US6486185B1 (en) | 1997-05-07 | 2002-11-26 | Sugen, Inc. | 3-heteroarylidene-2-indolinone protein kinase inhibitors |
| US6316429B1 (en) | 1997-05-07 | 2001-11-13 | Sugen, Inc. | Bicyclic protein kinase inhibitors |
| US6235769B1 (en) | 1997-07-03 | 2001-05-22 | Sugen, Inc. | Methods of preventing and treating neurological disorders with compounds that modulate the function of the C-RET receptor protein tyrosine kinase |
| AU3363599A (en) * | 1998-03-26 | 1999-10-18 | Max-Planck Institut Fur Biochemie | Heterocyclic families of compounds for the modulation of tyrosine protein kinase |
| US6514981B1 (en) | 1998-04-02 | 2003-02-04 | Sugen, Inc. | Methods of modulating tyrosine protein kinase function with indolinone compounds |
| US6864227B1 (en) | 1998-04-13 | 2005-03-08 | California Institute Of Technology | Artery-and vein-specific proteins and uses therefor |
| US6887674B1 (en) | 1998-04-13 | 2005-05-03 | California Institute Of Technology | Artery- and vein-specific proteins and uses therefor |
| US6395734B1 (en) | 1998-05-29 | 2002-05-28 | Sugen, Inc. | Pyrrole substituted 2-indolinone protein kinase inhibitors |
| US6689806B1 (en) | 1999-03-24 | 2004-02-10 | Sugen, Inc. | Indolinone compounds as kinase inhibitors |
| US6878733B1 (en) | 1999-11-24 | 2005-04-12 | Sugen, Inc. | Formulations for pharmaceutical agents ionizable as free acids or free bases |
| AU784266B2 (en) * | 1999-12-22 | 2006-03-02 | Sugen, Inc. | Indolinone derivatives for modulation of c-kit tyrosine kinase |
| US20020028828A1 (en) | 2000-05-02 | 2002-03-07 | Chung-Chen Wei | (2-oxindol-3-ylidenyl)acetic acid derivatives and their use as protein kinase inhibitors |
| EP1435959A2 (en) * | 2001-10-09 | 2004-07-14 | University of Cincinnati | Inhibitors of the egf receptor for the treatment of thyroid cancer |
| EP1605961A4 (en) | 2003-03-12 | 2009-11-11 | Vasgene Therapeutics Inc | Polypeptide compounds for inhibiting angiogenesis and tumor growth |
| US7381410B2 (en) | 2003-03-12 | 2008-06-03 | Vasgene Therapeutics, Inc. | Polypeptide compounds for inhibiting angiogenesis and tumor growth |
| BRPI0409567A (en) * | 2003-04-16 | 2006-04-18 | Wyeth Corp | process of modulating bone-related activity |
| ATE492564T1 (en) | 2004-03-12 | 2011-01-15 | Vasgene Therapeutics Inc | EPHB4-BINDING ANTIBODIES FOR INHIBITING ANGIOGENESIS AND TUMOR GROWTH |
| CN101072797B (en) | 2004-03-12 | 2012-05-09 | 瓦斯基因治疗公司 | Antibody binding EPHB4, inhibiting angiogenesis and tumor growth |
| AU2005286662B2 (en) | 2004-09-23 | 2011-10-06 | Vasgene Therapeutics, Inc. | Polypeptide compounds for inhibiting angiogenesis and tumor growth |
| NZ594466A (en) | 2005-12-08 | 2012-08-31 | Medarex Inc | Human monoclonal antibodies to protein tyrosine kinase 7 (PTK7) and methods for using anti-PTK7 antibodies |
| US7910324B2 (en) | 2007-06-08 | 2011-03-22 | Eisai R&D Management Co., Ltd. | Method of screening for compounds which affect the processing of EphA4 by γ-secretase |
| EP2192181A4 (en) * | 2007-08-01 | 2010-12-08 | Eisai R&D Man Co Ltd | Screening method utilizing novel substrate c-ret for gamma-secretase |
| JP5749009B2 (en) | 2007-08-13 | 2015-07-15 | バスジーン セラピューティクス，インコーポレイテッドＶａｓｇｅｎｅｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | Cancer therapeutic agent using humanized antibody binding to EphB4 |
| WO2009064006A1 (en) | 2007-11-15 | 2009-05-22 | Eisai R & D Management Co., Ltd. | SCREENING METHOD UTILIZING NOVEL SUBSTRATE EphA7 FOR γ-SECRETASE |
| EP2504024A2 (en) * | 2009-09-27 | 2012-10-03 | Ruhr-Universität Bochum | Method for the therapy and diagnosis of alzheimer's disease |
| US8865426B2 (en) | 2010-12-17 | 2014-10-21 | Eisai R&D Management Co., Ltd. | Screening method using gelatinase-mediated EphA4 cleavage reaction as an indicator |
| JP5961608B2 (en) | 2011-04-25 | 2016-08-02 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | Method for detecting neurological diseases accompanied by cognitive impairment by measuring EphA4 extracellular domain |
| EP3995582A4 (en) | 2019-07-01 | 2023-01-18 | Eisai R&D Management Co., Ltd. | Anti-epha4 antibody |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9501567D0 (en) * | 1995-01-26 | 1995-03-15 | Pharmacia Spa | Hydrosoluble 3-arylidene-2-oxindole derivatives as tyrosine kinase inhibitors |
-
1998
- 1998-04-07 AU AU68876/98A patent/AU6887698A/en not_active Abandoned
- 1998-04-07 WO PCT/US1998/006842 patent/WO1998045708A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO1998045708A1 (en) | 1998-10-15 |
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