AU6455896A - Novel factor viii:c polypeptide analogs with altered metal-binding properties - Google Patents
Novel factor viii:c polypeptide analogs with altered metal-binding propertiesInfo
- Publication number
- AU6455896A AU6455896A AU64558/96A AU6455896A AU6455896A AU 6455896 A AU6455896 A AU 6455896A AU 64558/96 A AU64558/96 A AU 64558/96A AU 6455896 A AU6455896 A AU 6455896A AU 6455896 A AU6455896 A AU 6455896A
- Authority
- AU
- Australia
- Prior art keywords
- factor viii
- binding properties
- polypeptide analogs
- novel factor
- altered metal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US87195P | 1995-07-11 | 1995-07-11 | |
US000871 | 1995-07-11 | ||
PCT/US1996/011438 WO1997003193A1 (en) | 1995-07-11 | 1996-07-09 | Novel factor viii:c polypeptide analogs with altered metal-binding properties |
Publications (1)
Publication Number | Publication Date |
---|---|
AU6455896A true AU6455896A (en) | 1997-02-10 |
Family
ID=21693379
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU64558/96A Abandoned AU6455896A (en) | 1995-07-11 | 1996-07-09 | Novel factor viii:c polypeptide analogs with altered metal-binding properties |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU6455896A (en) |
WO (1) | WO1997003193A1 (en) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6180371B1 (en) | 1996-06-26 | 2001-01-30 | Emory University | Modified factor VIII |
US5859204A (en) * | 1992-04-07 | 1999-01-12 | Emory University | Modified factor VIII |
US6458563B1 (en) | 1996-06-26 | 2002-10-01 | Emory University | Modified factor VIII |
US7560107B2 (en) | 1996-06-26 | 2009-07-14 | Emory University | Modified factor VIII |
WO2000039302A2 (en) | 1998-12-31 | 2000-07-06 | Chiron Corporation | Improved expression of hiv polypeptides and production of virus-like particles |
ES2449044T3 (en) | 2004-05-03 | 2014-03-18 | Emory University | Administration procedure of fVIII without porcine B domain |
EP1598367A1 (en) * | 2004-05-18 | 2005-11-23 | ZLB Behring GmbH | Modified coagulation factors with enhanced stability and their derivatives |
EP1816201A1 (en) | 2006-02-06 | 2007-08-08 | CSL Behring GmbH | Modified coagulation factor VIIa with extended half-life |
AU2007338298B2 (en) | 2006-12-22 | 2013-02-07 | Csl Behring Gmbh | Modified coagulation factors with prolonged in vivo half-life |
ES2654336T3 (en) | 2008-06-24 | 2018-02-13 | Csl Behring Gmbh | Factor VIII, von Willebrand factor or its complexes with prolonged in vivo half-life |
SG190136A1 (en) | 2010-11-05 | 2013-07-31 | Baxter Int | A new variant of antihemophilic factor viii having increased specific activity |
US9458223B2 (en) | 2012-02-15 | 2016-10-04 | Csl Behring Gmbh | Von willebrand factor variants having improved factor VIII binding affinity |
EP2796145B1 (en) | 2013-04-22 | 2017-11-01 | CSL Ltd. | A covalent complex of von willebrand factor and faktor viii linked by a disulphide bridge |
KR20170026580A (en) | 2014-07-02 | 2017-03-08 | 씨에스엘 리미티드 | Modified von willebrand factor |
SG11201706659WA (en) | 2015-03-06 | 2017-09-28 | Csl Behring Recombinant Facility Ag | Modified von willebrand factor having improved half-life |
AU2016266627A1 (en) | 2015-05-22 | 2018-01-18 | CSL Behring Lengnau AG | Truncated von Willebrand Factor polypeptides for treating hemophilia |
RU2017145002A (en) | 2015-05-22 | 2019-06-24 | Цсл Беринг Ленгнау Аг | METHODS OF OBTAINING A MODIFIED VILLE BRAND VON FACTOR |
ES2881701T3 (en) | 2016-01-07 | 2021-11-30 | CSL Behring Lengnau AG | Mutated von Willebrand factor |
RU2018128582A (en) | 2016-01-07 | 2020-02-11 | Цсл Беринг Ленгнау Аг | MUTED CROPPED VILLEBRAND BACKGROUND FACTOR |
KR20190085021A (en) | 2016-11-11 | 2019-07-17 | 체에스엘 베링 렝나우 아게 | A cut von Willebrand factor polypeptide to treat hemophilia |
TW201828974A (en) | 2016-11-11 | 2018-08-16 | 瑞士商Csl貝林重組技能公司 | Truncated von Willebrand factor polypeptides for extravascular administration in the treatment or prophylaxis of a blood coagulation disorder |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE465222C5 (en) * | 1989-12-15 | 1998-02-10 | Pharmacia & Upjohn Ab | A recombinant human factor VIII derivative and process for its preparation |
-
1996
- 1996-07-09 WO PCT/US1996/011438 patent/WO1997003193A1/en active Application Filing
- 1996-07-09 AU AU64558/96A patent/AU6455896A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
WO1997003193A1 (en) | 1997-01-30 |
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