AU6432986A - 1-methyl-15alpha -alkylandrosta-1, 4-diene-3, 17-diones - Google Patents

1-methyl-15alpha -alkylandrosta-1, 4-diene-3, 17-diones

Info

Publication number
AU6432986A
AU6432986A AU64329/86A AU6432986A AU6432986A AU 6432986 A AU6432986 A AU 6432986A AU 64329/86 A AU64329/86 A AU 64329/86A AU 6432986 A AU6432986 A AU 6432986A AU 6432986 A AU6432986 A AU 6432986A
Authority
AU
Australia
Prior art keywords
alkylandrosta
15alpha
diones
diene
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU64329/86A
Inventor
David Henderson
Ulrich Kerb
Yukishige Nishino
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Publication of AU6432986A publication Critical patent/AU6432986A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

1. m¢ethyl-15alpha-alkylandrosta-1,4-dienes-3,17-diones of the general formula I see diagramm : EP0225272,P12,F1 in which R15 is an alkyl group of 1 to 4 carbon atoms, which may be substituted in the 1 and/or 2 position by a hydroxy or a C2 -C7 alkanoyloxy group or a 1,2-isopropylidenedioxy group.
AU64329/86A 1985-11-01 1986-10-23 1-methyl-15alpha -alkylandrosta-1, 4-diene-3, 17-diones Abandoned AU6432986A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3539244 1985-11-01
DE19853539244 DE3539244A1 (en) 1985-11-01 1985-11-01 1-METHYL-15 (ALPHA) -ALKYL-ANDROSTA- 1,4-DIEN-3,17-DIONE, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM

Publications (1)

Publication Number Publication Date
AU6432986A true AU6432986A (en) 1987-05-07

Family

ID=6285220

Family Applications (1)

Application Number Title Priority Date Filing Date
AU64329/86A Abandoned AU6432986A (en) 1985-11-01 1986-10-23 1-methyl-15alpha -alkylandrosta-1, 4-diene-3, 17-diones

Country Status (16)

Country Link
EP (1) EP0225272B1 (en)
JP (1) JPS62155294A (en)
CN (1) CN86107158A (en)
AT (1) ATE41936T1 (en)
AU (1) AU6432986A (en)
DD (1) DD250319A5 (en)
DE (2) DE3539244A1 (en)
DK (1) DK515486A (en)
FI (1) FI864329A (en)
GR (1) GR880300115T1 (en)
HU (1) HU196079B (en)
IL (1) IL80176A0 (en)
NO (1) NO864365L (en)
NZ (1) NZ218071A (en)
PT (1) PT83659B (en)
ZA (1) ZA868333B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3703722A1 (en) * 1987-02-04 1988-08-18 Schering Ag 1-METHYL-15 (ALPHA) - (1,2-DIALKANOYLOXYALKYL) -ANDROSTA-1,4-DIEN-3,17-DIONE, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM
DE3705990A1 (en) * 1987-02-20 1988-09-01 Schering Ag 1-METHYL-15 (ALPHA) - (1-OXYALKYL) -ANDROSTA-1,4-DIEN-3,17-DIONE, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM
DE3715869A1 (en) * 1987-05-07 1988-11-17 Schering Ag METHOD FOR PRODUCING 1-METHYL-ANDROSTA-1,4-DIEN-3,17-DION AND THE NEW INTERMEDIATE PRODUCTS FOR THIS METHOD
CH683151A5 (en) * 1991-04-24 1994-01-31 Ciba Geigy Ag Contraception in female primates without affecting the menstrual cycle.
DE4435368A1 (en) * 1994-09-22 1996-03-28 Schering Ag Use of aromatase inhibitors for the manufacture of a medicament for the treatment of a relative androgen deficiency in men

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3766224A (en) * 1971-06-03 1973-10-16 Sandoz Ag 15-methyl-substituted steroids
DE3322285A1 (en) * 1983-06-18 1984-12-20 Schering AG, 1000 Berlin und 4709 Bergkamen 1-ALKYL-ANDROSTA-1,4-DIEN-3,17-DIONE, METHOD FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM

Also Published As

Publication number Publication date
HUT43618A (en) 1987-11-30
GR880300115T1 (en) 1989-06-22
NO864365D0 (en) 1986-10-31
NZ218071A (en) 1989-01-06
HU196079B (en) 1988-09-28
CN86107158A (en) 1987-08-05
DE3662693D1 (en) 1989-05-11
FI864329A0 (en) 1986-10-24
JPS62155294A (en) 1987-07-10
ZA868333B (en) 1987-06-24
PT83659B (en) 1988-08-30
FI864329A (en) 1987-05-02
ATE41936T1 (en) 1989-04-15
DD250319A5 (en) 1987-10-08
DK515486D0 (en) 1986-10-28
NO864365L (en) 1987-05-04
DE3539244A1 (en) 1987-05-07
IL80176A0 (en) 1986-12-31
EP0225272B1 (en) 1989-04-05
DK515486A (en) 1987-05-02
PT83659A (en) 1986-11-01
EP0225272A1 (en) 1987-06-10

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