AU630725B2 - 2-amino-7-carbamoyl-1,2,3,4-tetrahydronaphthalenes, process for preparing them and their use as drugs - Google Patents

2-amino-7-carbamoyl-1,2,3,4-tetrahydronaphthalenes, process for preparing them and their use as drugs

Info

Publication number: AU630725B2
Authority: AU; Australia
Prior art keywords: tetrahydronaphthalenes; carbamoyl; drugs; amino; preparing
Prior art date: 1989-07-22
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

AU59586/90A

Other versions

AU5958690A (en

Inventor

Matthias Grauert

Herbert Merz

Joachim Mierau

Gunter Schingnitz

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Boehringer Ingelheim International GmbH

Original Assignee

Boehringer Ingelheim International GmbH

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-07-22

Filing date

1990-07-18

Publication date

1992-11-05

1990-07-18 Application filed by Boehringer Ingelheim International GmbH filed Critical Boehringer Ingelheim International GmbH

1991-02-22 Publication of AU5958690A publication Critical patent/AU5958690A/en

1992-11-05 Application granted granted Critical

1992-11-05 Publication of AU630725B2 publication Critical patent/AU630725B2/en

2010-07-18 Anticipated expiration legal-status Critical

Status Ceased legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/58—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/48—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring being part of a condensed ring system of the same carbon skeleton
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/04—One of the condensed rings being a six-membered aromatic ring
- C07C2602/10—One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Engineering & Computer Science (AREA)
Animal Behavior & Ethology (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

AU59586/90A 1989-07-22 1990-07-18 2-amino-7-carbamoyl-1,2,3,4-tetrahydronaphthalenes, process for preparing them and their use as drugs Ceased AU630725B2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DE3924365A DE3924365A1 (en)	1989-07-22	1989-07-22	2-AMINO-7-CARBAMOYL-1,2,3,4-TETRAHYDRONAPHTHALINE, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS A MEDICAMENT
DE3924365		1989-07-22

Publications (2)

Publication Number	Publication Date
AU5958690A AU5958690A (en)	1991-02-22
AU630725B2 true AU630725B2 (en)	1992-11-05

Family

ID=6385664

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU59586/90A Ceased AU630725B2 (en)	1989-07-22	1990-07-18	2-amino-7-carbamoyl-1,2,3,4-tetrahydronaphthalenes, process for preparing them and their use as drugs

Country Status (13)

Country	Link
EP (1)	EP0435988A1 (en)
JP (1)	JPH04500815A (en)
KR (1)	KR920701133A (en)
AU (1)	AU630725B2 (en)
CA (1)	CA2033323A1 (en)
DD (1)	DD297401A5 (en)
DE (1)	DE3924365A1 (en)
IE (1)	IE902655A1 (en)
IL (1)	IL95142A0 (en)
NZ (1)	NZ234590A (en)
PT (1)	PT94780A (en)
WO (1)	WO1991001297A1 (en)
ZA (1)	ZA905715B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2123500T3 (en) *	1989-05-31	1999-01-16	Upjohn Co	DERIVATIVES OF 8-HETEROCICLIL-2-AMINOTETRALINA ACTIVE ON THE CENTRAL NERVOUS SYSTEM.
EP0499755A1 (en) *	1991-02-18	1992-08-26	MIDY S.p.A.	Phenylethanolaminotetralines, process for their preparation, intermediates of this process and pharmaceutical compositions containing them
DK148292D0 (en) *	1992-12-09	1992-12-09	Lundbeck & Co As H	RELATIONS
WO2007081542A2 (en) *	2006-01-06	2007-07-19	Sepracor Inc.	Tetralone-based monoamine reuptake inhibitors

Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU8302987A (en) *	1986-12-22	1988-06-30	Bayer Aktiengesellschaft	8-substituted 2-aminotetralins
AU5822190A (en) *	1989-05-31	1991-01-07	Pharmacia & Upjohn Company	Therapeutically useful 2-aminotetralin derivatives

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4448990A (en) *	1982-11-16	1984-05-15	Eli Lilly And Company	Hydroxyaminotetralincarboxamides

1989
- 1989-07-22 DE DE3924365A patent/DE3924365A1/en not_active Withdrawn
1990
- 1990-07-18 EP EP90910685A patent/EP0435988A1/en not_active Withdrawn
- 1990-07-18 KR KR1019910700299A patent/KR920701133A/en not_active Application Discontinuation
- 1990-07-18 WO PCT/EP1990/001174 patent/WO1991001297A1/en not_active Application Discontinuation
- 1990-07-18 CA CA002033323A patent/CA2033323A1/en not_active Abandoned
- 1990-07-18 JP JP2509979A patent/JPH04500815A/en active Pending
- 1990-07-18 AU AU59586/90A patent/AU630725B2/en not_active Ceased
- 1990-07-19 DD DD90342912A patent/DD297401A5/en not_active IP Right Cessation
- 1990-07-20 IE IE265590A patent/IE902655A1/en unknown
- 1990-07-20 ZA ZA905715A patent/ZA905715B/en unknown
- 1990-07-20 PT PT94780A patent/PT94780A/en not_active Application Discontinuation
- 1990-07-20 IL IL95142A patent/IL95142A0/en unknown
- 1990-07-20 NZ NZ234590A patent/NZ234590A/en unknown

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU8302987A (en) *	1986-12-22	1988-06-30	Bayer Aktiengesellschaft	8-substituted 2-aminotetralins
AU5822190A (en) *	1989-05-31	1991-01-07	Pharmacia & Upjohn Company	Therapeutically useful 2-aminotetralin derivatives

Also Published As

Publication number	Publication date
EP0435988A1 (en)	1991-07-10
CA2033323A1 (en)	1991-01-23
ZA905715B (en)	1992-03-25
IE902655A1 (en)	1991-02-27
PT94780A (en)	1991-03-20
KR920701133A (en)	1992-08-11
DD297401A5 (en)	1992-01-09
DE3924365A1 (en)	1991-01-24
IL95142A0 (en)	1991-06-10
NZ234590A (en)	1992-07-28
WO1991001297A1 (en)	1991-02-07
JPH04500815A (en)	1992-02-13
AU5958690A (en)	1991-02-22

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