AU6232794A - The use of nitric oxide-delivering compounds for the treatment or prevention of alcoholic liver injury - Google Patents

The use of nitric oxide-delivering compounds for the treatment or prevention of alcoholic liver injury

Info

Publication number
AU6232794A
AU6232794A AU62327/94A AU6232794A AU6232794A AU 6232794 A AU6232794 A AU 6232794A AU 62327/94 A AU62327/94 A AU 62327/94A AU 6232794 A AU6232794 A AU 6232794A AU 6232794 A AU6232794 A AU 6232794A
Authority
AU
Australia
Prior art keywords
prevention
treatment
nitric oxide
liver injury
alcoholic liver
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU62327/94A
Inventor
Joseph Loscalzo
Amin Nanji
Jonathan Stamler
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Brigham and Womens Hospital Inc
Beth Israel Deaconess Medical Center Inc
Original Assignee
Brigham and Womens Hospital Inc
New England Deaconess Hospital
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Brigham and Womens Hospital Inc, New England Deaconess Hospital filed Critical Brigham and Womens Hospital Inc
Publication of AU6232794A publication Critical patent/AU6232794A/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/06Tripeptides
    • A61K38/063Glutathione
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/28Compounds containing heavy metals
    • A61K31/295Iron group metal compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/38Albumins

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AU62327/94A 1993-01-29 1994-01-27 The use of nitric oxide-delivering compounds for the treatment or prevention of alcoholic liver injury Abandoned AU6232794A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US1213593A 1993-01-29 1993-01-29
US012135 1993-01-29
PCT/US1994/000970 WO1994016740A1 (en) 1993-01-29 1994-01-27 The use of nitric oxide-delivering compounds for the treatment or prevention of alcoholic liver injury

Publications (1)

Publication Number Publication Date
AU6232794A true AU6232794A (en) 1994-08-15

Family

ID=21753553

Family Applications (1)

Application Number Title Priority Date Filing Date
AU62327/94A Abandoned AU6232794A (en) 1993-01-29 1994-01-27 The use of nitric oxide-delivering compounds for the treatment or prevention of alcoholic liver injury

Country Status (2)

Country Link
AU (1) AU6232794A (en)
WO (1) WO1994016740A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6232434B1 (en) 1996-08-02 2001-05-15 Duke University Medical Center Polymers for delivering nitric oxide in vivo
US6346382B1 (en) 1999-06-01 2002-02-12 Vanderbilt University Human carbamyl phosphate synthetase I polymorphism and diagnostic methods related thereto
US9486429B2 (en) * 1999-06-01 2016-11-08 Vanderbilt University Therapeutic methods employing nitric oxide precursors
US8066904B2 (en) 2001-09-05 2011-11-29 Geno Llc Controlled generation of nitric oxide
US7618594B2 (en) 2004-08-18 2009-11-17 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
JP5421530B2 (en) 2004-08-18 2014-02-19 ゲノ エルエルシー Conversion of nitrogen dioxide (NO2) to nitrogen oxide (NO)
SE0402221D0 (en) 2004-09-14 2004-09-14 Aerocrine Ab Treatment of insufficient perfusion
WO2007121545A1 (en) * 2006-04-20 2007-11-01 Universidade Estadual De Campinas-Unicamp S-nitrosothiols containing compositions for the treatment of fatty liver diseases, obesity and other diseases associated with the metabolic syndrome and the use of such compositions
US7947227B2 (en) 2007-03-23 2011-05-24 Geno Llc Kit for the conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
US7914743B2 (en) 2008-01-28 2011-03-29 Geno Llc Conversion of nitrogen dioxide (NO2) to nitric oxide (NO)
SG196863A1 (en) 2008-01-31 2014-02-13 Univ Vanderbilt Methods and compositions for treatment for coronary and arterial aneurysmal subarachnoid hemorrhage
US8607785B2 (en) 2008-08-21 2013-12-17 Geno Llc Systems and devices for generating nitric oxide
EP2445508B1 (en) 2009-06-22 2018-11-14 VERO Biotech LLC Nitric oxide therapies
AU2010321707B2 (en) 2009-11-20 2016-03-17 VERO Biotech LLC. Nitric oxide delivery system
US11193077B1 (en) 2013-03-13 2021-12-07 Airworthy Autogas, Llc Gasoline for aircraft use
JP6595470B2 (en) * 2013-07-31 2019-10-23 ザ・チルドレンズ・ホスピタル・オブ・フィラデルフィア Compositions and methods for treating fatty acid metabolism disorders
CA3008395A1 (en) 2015-11-06 2017-05-11 The Children's Hospital Of Philadelphia Compositions and methods for the treatment of fatty acid metabolism disorders
GB2579240B (en) 2018-11-27 2020-12-16 Attgeno Ab New processes, compositions and medical uses
GB202007929D0 (en) 2020-05-27 2020-07-08 Attgeno Ab New medical uses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950529A (en) * 1975-02-03 1976-04-13 Massachusetts General Hospital Amino acid formulations for patients with liver disease and method of using same
JPH01216924A (en) * 1988-02-24 1989-08-30 Ajinomoto Co Inc Therapeutic agent for hepatic disorder

Also Published As

Publication number Publication date
WO1994016740A1 (en) 1994-08-04

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