AU6105300A - Vinyl ether lipids with cleavable hydrophilic headgroups - Google Patents

Vinyl ether lipids with cleavable hydrophilic headgroups

Info

Publication number
AU6105300A
AU6105300A AU61053/00A AU6105300A AU6105300A AU 6105300 A AU6105300 A AU 6105300A AU 61053/00 A AU61053/00 A AU 61053/00A AU 6105300 A AU6105300 A AU 6105300A AU 6105300 A AU6105300 A AU 6105300A
Authority
AU
Australia
Prior art keywords
vinyl ether
ether lipids
hydrophilic headgroups
cleavable hydrophilic
cleavable
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU61053/00A
Inventor
Jeremy A. Boomer
Robert Haynes
David H Thompson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Purdue Research Foundation
Original Assignee
Purdue Research Foundation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Purdue Research Foundation filed Critical Purdue Research Foundation
Publication of AU6105300A publication Critical patent/AU6105300A/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Liposomes
    • A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
    • A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers with substantial amounts of non-phosphatidyl, i.e. non-acylglycerophosphate, surfactants as bilayer-forming substances, e.g. cationic lipids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Biophysics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
AU61053/00A 1999-07-16 2000-07-17 Vinyl ether lipids with cleavable hydrophilic headgroups Abandoned AU6105300A (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US14430199P 1999-07-16 1999-07-16
US60144301 1999-07-16
US14655299P 1999-07-30 1999-07-30
US60146552 1999-07-30
PCT/US2000/019430 WO2001005375A1 (en) 1999-07-16 2000-07-17 Vinyl ether lipids with cleavable hydrophilic headgroups

Publications (1)

Publication Number Publication Date
AU6105300A true AU6105300A (en) 2001-02-05

Family

ID=26841867

Family Applications (1)

Application Number Title Priority Date Filing Date
AU61053/00A Abandoned AU6105300A (en) 1999-07-16 2000-07-17 Vinyl ether lipids with cleavable hydrophilic headgroups

Country Status (3)

Country Link
EP (1) EP1202714A1 (en)
AU (1) AU6105300A (en)
WO (1) WO2001005375A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005521645A (en) 2001-12-04 2005-07-21 ベン グリオン ユニバーシティ オブ ザ ネジェブ リサーチ アンド ディベラップメント オーソリティ Amphiphilic compounds and vesicles / liposomes for organ-specific drug targeting
EP1498420B1 (en) 2002-03-29 2017-02-01 Nof Corporation Phospholipid derivative
AU2003266714A1 (en) 2002-09-30 2004-04-19 Daiichi Pharmaceutical Co., Ltd. Phospholipid derivative
CN100339382C (en) 2003-01-06 2007-09-26 日本油脂株式会社 Phospholipid derivatives and process for the production there
JP4526479B2 (en) 2003-03-20 2010-08-18 日油株式会社 Phospholipid derivative
ES2734973T3 (en) 2009-12-01 2019-12-13 Translate Bio Inc Administration of mRNA for the increase of proteins and enzymes in human genetic diseases
EP2717893B1 (en) 2011-06-08 2019-05-08 Translate Bio, Inc. Lipid nanoparticle compositions and methods for mrna delivery
EP2718269B1 (en) 2011-06-08 2018-01-31 Translate Bio, Inc. Cleavable lipids
DK2830595T3 (en) 2012-03-29 2019-12-02 Translate Bio Inc IONIZABLE CATIONIC LIPIDS
JP6211054B2 (en) 2012-03-29 2017-10-11 シャイアー ヒューマン ジェネティック セラピーズ インコーポレイテッド Lipid-induced neutral nanoparticles
WO2013185067A1 (en) 2012-06-08 2013-12-12 Shire Human Genetic Therapies, Inc. Nuclease resistant polynucleotides and uses thereof
EP3467108B1 (en) 2013-03-14 2024-05-22 Translate Bio, Inc. Methods for purification of messenger rna
IL290953B2 (en) 2013-03-14 2024-01-01 Ethris Gmbh Cftr mrna compositions and related methods and uses
EP3060258A1 (en) 2013-10-22 2016-08-31 Shire Human Genetic Therapies, Inc. Mrna therapy for phenylketonuria
EP3060257B1 (en) 2013-10-22 2021-02-24 Translate Bio, Inc. Lipid formulations for delivery of messenger rna
MX2016005237A (en) 2013-10-22 2016-08-12 Shire Human Genetic Therapies Mrna therapy for argininosuccinate synthetase deficiency.
CN117402871A (en) 2014-04-25 2024-01-16 川斯勒佰尔公司 Method for purifying messenger RNA
EP3148552B1 (en) 2014-05-30 2019-07-31 Translate Bio, Inc. Biodegradable lipids for delivery of nucleic acids
NZ727281A (en) 2014-06-24 2024-02-23 Translate Bio Inc Stereochemically enriched compositions for delivery of nucleic acids
US20180153822A1 (en) * 2016-11-10 2018-06-07 Translate Bio, Inc. Process of Preparing mRNA-Loaded Lipid Nanoparticles
EA201991747A1 (en) 2017-02-27 2020-06-04 Транслейт Био, Инк. NEW CODON-OPTIMIZED CFTR mRNA
CA3063531A1 (en) 2017-05-16 2018-11-22 Translate Bio, Inc. Treatment of cystic fibrosis by delivery of codon-optimized mrna encoding cftr
US11174500B2 (en) 2018-08-24 2021-11-16 Translate Bio, Inc. Methods for purification of messenger RNA

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5277913A (en) * 1991-09-09 1994-01-11 Thompson David H Liposomal delivery system with photoactivatable triggered release

Also Published As

Publication number Publication date
EP1202714A1 (en) 2002-05-08
WO2001005375A1 (en) 2001-01-25

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase