AU6069486A - Cephalosporin salts and injectable compositions - Google Patents

Cephalosporin salts and injectable compositions

Info

Publication number: AU6069486A
Authority: AU; Australia
Prior art keywords: injectable compositions; cephalosporin salts; cephalosporin; salts; injectable
Prior art date: 1985-08-05
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Granted

Application number

AU60694/86A

Other versions

AU597262B2 (en

Inventor

Thomas W. Hudyma

Murray A. Kaplan

Robert A. Lipper

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Bristol Myers Squibb Co

Original Assignee

Bristol Myers Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-08-05

Filing date

1986-07-30

Publication date

1987-02-12

1986-07-30 Application filed by Bristol Myers Co filed Critical Bristol Myers Co

1987-02-12 Publication of AU6069486A publication Critical patent/AU6069486A/en

1990-05-31 Application granted granted Critical

1990-05-31 Publication of AU597262B2 publication Critical patent/AU597262B2/en

2006-07-30 Anticipated expiration legal-status Critical

Status Expired legal-status Critical Current

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/38—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof
- C07D501/46—Methylene radicals, substituted by nitrogen atoms; Lactams thereof with the 2-carboxyl group; Methylene radicals substituted by nitrogen-containing hetero rings attached by the ring nitrogen atom; Quaternary compounds thereof with the 7-amino radical acylated by carboxylic acids containing hetero rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Oncology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Communicable Diseases (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Cephalosporin Compounds (AREA)
Medicinal Preparation (AREA)

AU60694/86A 1985-08-05 1986-07-30 Cephalosporin salts and injectable compositions Expired AU597262B2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US76223585A	1985-08-05	1985-08-05
US762235		1985-08-05

Publications (2)

Publication Number	Publication Date
AU6069486A true AU6069486A (en)	1987-02-12
AU597262B2 AU597262B2 (en)	1990-05-31

Family

ID=25064475

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU60694/86A Expired AU597262B2 (en)	1985-08-05	1986-07-30	Cephalosporin salts and injectable compositions

Country Status (34)

Country	Link
JP (1)	JPH0615548B2 (en)
KR (1)	KR930003121B1 (en)
AR (1)	AR243894A1 (en)
AT (1)	AT390957B (en)
AU (1)	AU597262B2 (en)
BE (1)	BE905219A (en)
CA (1)	CA1284994C (en)
CH (1)	CH675581A5 (en)
CS (2)	CS276849B6 (en)
CY (1)	CY1614A (en)
DD (2)	DD254941A5 (en)
DE (1)	DE3626375A1 (en)
DK (1)	DK162053C (en)
EG (1)	EG18003A (en)
ES (1)	ES2002112A6 (en)
FI (1)	FI84484C (en)
FR (1)	FR2585705B1 (en)
GB (1)	GB2179936B (en)
GR (1)	GR862055B (en)
HK (1)	HK99691A (en)
HU (1)	HU196602B (en)
IE (1)	IE59222B1 (en)
IL (1)	IL79608A (en)
IT (1)	IT1197067B (en)
LU (2)	LU86540A1 (en)
MY (1)	MY102212A (en)
NL (1)	NL8601991A (en)
OA (1)	OA08672A (en)
PT (1)	PT83134B (en)
SE (1)	SE469633B (en)
SG (1)	SG79791G (en)
SU (1)	SU1516013A3 (en)
YU (1)	YU45793B (en)
ZA (1)	ZA865842B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4883868A (en) *	1984-12-27	1989-11-28	Banyu Pharmaceutical Co., Ltd.	7-amino-3-(substituted isoindolinium)methyl-3-cephem derivatives
US4959469A (en) *	1984-12-27	1990-09-25	Banyu Pharmaceutical Company, Ltd.	Crystalline cephalosporin compounds
US4910301A (en) *	1985-08-05	1990-03-20	Bristol-Myers Company	Cefepime cephalosporin salts
US5244891A (en) *	1985-08-05	1993-09-14	Bristol-Myers Squibb Company	Injectable compositions of cefepime dihydrochloride hydrate
US4808617A (en) *	1985-12-18	1989-02-28	Bristol-Myers Company	Lyophilized or precipitated cephalosporin zwitterion and salt combination
EP0321562B1 (en) *	1987-06-25	1993-11-24	Banyu Pharmaceutical Co., Ltd.	Crystalline cephalosporin compounds, process for their preparation, and intermediates for their preparation
JPH02101081A (en) *	1988-10-08	1990-04-12	Meiji Seika Kaisha Ltd	Crystalline dihydrochloride of cephalosporin derivative and production thereof
CA2011116C (en) *	1989-03-06	1999-11-16	Murray A. Kaplan	Lyophilized bmy-28142 dihydrochloride for parenteral use
CA2101571A1 (en) *	1992-09-08	1994-03-09	Elizabeth A. Garofalo	Crystalline dihydrate of a cephalosporin dihydrate salt and injectable compositions thereof
EP0638573A1 (en) *	1993-08-10	1995-02-15	Lucky Ltd.	Crystalline hydrates of cephalosporin and process for preparation thereof
DE602004011685T2 (en)	2003-12-23	2009-02-05	Sandoz Gmbh	PROCESS FOR PREPARING INTERMEDIATE PRODUCTS FOR USE IN THE CEFALOSPORIN SYNTHESIS
WO2008056221A2 (en) *	2006-11-06	2008-05-15	Orchid Chemicals & Pharmaceuticals Limited	Crystalline sulfate salt of cephalosporin antibiotic
DE102012101680A1 (en) *	2012-02-29	2013-08-29	Aicuris Gmbh & Co. Kg	Pharmaceutical preparation containing an antiviral dihydroquinazoline derivative

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS55151588A (en) *	1979-05-14	1980-11-26	Takeda Chem Ind Ltd	Preparation of cephalosporin salt crystal
CA1213882A (en) *	1982-03-04	1986-11-12	Jun Okumura	Cephalosporins
US4406899A (en) *	1982-03-04	1983-09-27	Bristol-Myers Company	Cephalosporins
US4525473A (en) *	1983-03-30	1985-06-25	Bristol-Myers Company	Cephalosporins
DE3419015A1 (en) *	1984-05-22	1985-11-28	Bayer Ag, 5090 Leverkusen	METHOD FOR PRODUCING CEPHALOSPORINES
GB8424692D0 (en) *	1984-10-01	1984-11-07	Glaxo Group Ltd	Chemical compounds
GB2165245B (en) *	1984-10-01	1988-05-25	Glaxo Group Ltd	Chemical compounds

1986
- 1986-07-28 FR FR8610892A patent/FR2585705B1/en not_active Expired
- 1986-07-28 CA CA000514766A patent/CA1284994C/en not_active Expired - Lifetime
- 1986-07-29 AR AR86304717A patent/AR243894A1/en active
- 1986-07-30 AU AU60694/86A patent/AU597262B2/en not_active Expired
- 1986-07-31 YU YU137186A patent/YU45793B/en unknown
- 1986-08-01 FI FI863155A patent/FI84484C/en not_active IP Right Cessation
- 1986-08-01 IE IE207886A patent/IE59222B1/en not_active IP Right Cessation
- 1986-08-04 DE DE19863626375 patent/DE3626375A1/en not_active Ceased
- 1986-08-04 IT IT21409/86A patent/IT1197067B/en active Protection Beyond IP Right Term
- 1986-08-04 NL NL8601991A patent/NL8601991A/en not_active Application Discontinuation
- 1986-08-04 IL IL79608A patent/IL79608A/en not_active IP Right Cessation
- 1986-08-04 GR GR862055A patent/GR862055B/en unknown
- 1986-08-04 CS CS903570A patent/CS276849B6/en unknown
- 1986-08-04 SU SU864027914A patent/SU1516013A3/en active
- 1986-08-04 JP JP61183288A patent/JPH0615548B2/en not_active Expired - Lifetime
- 1986-08-04 ZA ZA865842A patent/ZA865842B/en unknown
- 1986-08-04 BE BE07217010A patent/BE905219A/en not_active IP Right Cessation
- 1986-08-04 SE SE8603308A patent/SE469633B/en not_active IP Right Cessation
- 1986-08-04 PT PT83134A patent/PT83134B/en unknown
- 1986-08-04 LU LU86540A patent/LU86540A1/en unknown
- 1986-08-04 DK DK371886A patent/DK162053C/en not_active IP Right Cessation
- 1986-08-04 CH CH3117/86A patent/CH675581A5/de not_active IP Right Cessation
- 1986-08-04 CS CS865827A patent/CS276717B6/en unknown
- 1986-08-04 GB GB8618989A patent/GB2179936B/en not_active Expired
- 1986-08-04 LU LU88574C patent/LU88574I2/en unknown
- 1986-08-05 ES ES8600872A patent/ES2002112A6/en not_active Expired
- 1986-08-05 DD DD86293433A patent/DD254941A5/en unknown
- 1986-08-05 OA OA58918A patent/OA08672A/en unknown
- 1986-08-05 HU HU863376A patent/HU196602B/en unknown
- 1986-08-05 KR KR1019860006445A patent/KR930003121B1/en not_active IP Right Cessation
- 1986-08-05 AT AT0211086A patent/AT390957B/en not_active IP Right Cessation
1987
- 1987-09-29 MY MYPI87002279A patent/MY102212A/en unknown
1988
- 1988-03-30 DD DD88314213A patent/DD268395A5/en unknown
1989
- 1989-08-04 EG EG489/86A patent/EG18003A/en active
1991
- 1991-10-02 SG SG797/91A patent/SG79791G/en unknown
- 1991-12-05 HK HK996/91A patent/HK99691A/en not_active IP Right Cessation
1992
- 1992-07-10 CY CY1614A patent/CY1614A/en unknown

Also Published As

Publication number	Publication date
SE8603308D0 (en)	1986-08-04
CS276717B6 (en)	1992-08-12
IE59222B1 (en)	1994-01-26
KR930003121B1 (en)	1993-04-19
SE8603308L (en)	1987-02-06
FR2585705B1 (en)	1989-01-13
DE3626375A1 (en)	1987-02-12
AU597262B2 (en)	1990-05-31
FR2585705A1 (en)	1987-02-06
JPH0615548B2 (en)	1994-03-02
IT8621409A1 (en)	1988-02-04
ZA865842B (en)	1987-04-29
DK162053C (en)	1992-02-10
DD254941A5 (en)	1988-03-16
FI84484B (en)	1991-08-30
IL79608A0 (en)	1986-11-30
AT390957B (en)	1990-07-25
YU45793B (en)	1992-07-20
HU196602B (en)	1988-12-28
FI84484C (en)	1991-12-10
PT83134B (en)	1989-07-31
GB2179936B (en)	1989-04-26
CA1284994C (en)	1991-06-18
DD268395A5 (en)	1989-05-31
IL79608A (en)	1991-07-18
GB8618989D0 (en)	1986-09-17
GR862055B (en)	1986-12-24
BE905219A (en)	1987-02-04
IE862078L (en)	1987-02-05
FI863155A0 (en)	1986-08-01
IT1197067B (en)	1988-11-25
FI863155A (en)	1987-02-06
SG79791G (en)	1991-11-15
JPS62103090A (en)	1987-05-13
DK162053B (en)	1991-09-09
CH675581A5 (en)	1990-10-15
OA08672A (en)	1989-03-31
IT8621409A0 (en)	1986-08-04
PT83134A (en)	1986-09-01
SU1516013A3 (en)	1989-10-15
CS276849B6 (en)	1992-08-12
SE469633B (en)	1993-08-09
AR243894A1 (en)	1993-09-30
LU88574I2 (en)	1995-03-01
ES2002112A6 (en)	1988-07-16
DK371886A (en)	1987-02-06
GB2179936A (en)	1987-03-18
HK99691A (en)	1991-12-13
CY1614A (en)	1992-07-10
MY102212A (en)	1992-05-15
NL8601991A (en)	1987-03-02
DK371886D0 (en)	1986-08-04
HUT41802A (en)	1987-05-28
KR880002530A (en)	1988-05-09
EG18003A (en)	1991-08-30
ATA211086A (en)	1990-01-15
LU86540A1 (en)	1987-03-06
YU137186A (en)	1987-12-31

Publication	Publication Date	Title
ZA89407B (en)	1989-09-27	Cephalosporin salts and injectable compositions
NZ215333A (en)	1988-09-29	Cephem compounds and pharmaceutical compositions
AU6069486A (en)	1987-02-12	Cephalosporin salts and injectable compositions
PH23045A (en)	1989-03-10	Cephem derivative and composition containing said compound
AU628664B2 (en)	1992-09-17	Cephalosporin compound and pharmaceutical composition thereof
NZ212320A (en)	1988-09-29	Cephalosporin derivatives and pharmaceutical compositions
NZ215717A (en)	1989-06-28	Cephalosporin derivatives
AU575715B2 (en)	1988-08-04	Lubricating composition with naphenate salts and polyesters
AU6697086A (en)	1987-07-02	Immunoamplifiers and related compositions
AU5556886A (en)	1986-11-06	O-sulfated beta-lactam hydrozamic acids
PH23442A (en)	1989-08-07	Cephalosporin derivatives and salts thereof
AU578677B2 (en)	1988-11-03	cephalosporin derivatives and salts thereof
AU608505B2 (en)	1991-04-11	Anaerobe-selective antibacterial compositions and methods
NZ217519A (en)	1990-07-26	Carbapenem antibiotics and compositions
AU4354385A (en)	1985-11-28	Cephalosporin derivatives
NZ210761A (en)	1988-08-30	Cephalosporin derivatives and pharmaceutical compositions
PH21201A (en)	1987-08-19	Cephalosporin derivatives and salts thereof
NZ216624A (en)	1988-08-30	Cephalosporins and pharmaceutical compositions
IL88959A (en)	1992-02-16	Cephalosporin salts and injectable compositions
AU557332B2 (en)	1986-12-18	Cephalosporin derivatives
AU584152B2 (en)	1989-05-18	Copolyestercarbonate composition
IE850040L (en)	1985-10-02	Cephalosporin derivatives
IE850448L (en)	1986-01-19	Cephalosporin derivatives
IL79200A0 (en)	1986-09-30	Cephalosporin derivatives
ZA862347B (en)	1986-11-26	Cephalosporin derivatives