AU5962694A - Producing cells for transplantation to reduce host rejection and resulting cells - Google Patents

Producing cells for transplantation to reduce host rejection and resulting cells

Info

Publication number
AU5962694A
AU5962694A AU59626/94A AU5962694A AU5962694A AU 5962694 A AU5962694 A AU 5962694A AU 59626/94 A AU59626/94 A AU 59626/94A AU 5962694 A AU5962694 A AU 5962694A AU 5962694 A AU5962694 A AU 5962694A
Authority
AU
Australia
Prior art keywords
cells
transplantation
host rejection
reduce host
resulting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU59626/94A
Inventor
Paul J Leibowitz
Samuel C Wadsworth
Chee-Wai Woon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Exemplar Corp
Original Assignee
Exemplar Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Exemplar Corp filed Critical Exemplar Corp
Publication of AU5962694A publication Critical patent/AU5962694A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/02—Animal zootechnically ameliorated
    • A01K2267/025—Animal producing cells or organs for transplantation
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00—Animals characterised by purpose
    • A01K2267/03—Animal model, e.g. for test or diseases
    • A01K2267/035—Animal model for multifactorial diseases
    • A01K2267/0381—Animal model for diseases of the hematopoietic system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
AU59626/94A 1992-12-31 1993-12-30 Producing cells for transplantation to reduce host rejection and resulting cells Abandoned AU5962694A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US99910092A 1992-12-31 1992-12-31
US999100 1992-12-31
PCT/US1993/012670 WO1994016065A1 (en) 1992-12-31 1993-12-30 Producing cells for transplantation to reduce host rejection and resulting cells

Publications (1)

Publication Number Publication Date
AU5962694A true AU5962694A (en) 1994-08-15

Family

ID=25545902

Family Applications (1)

Application Number Title Priority Date Filing Date
AU59626/94A Abandoned AU5962694A (en) 1992-12-31 1993-12-30 Producing cells for transplantation to reduce host rejection and resulting cells

Country Status (2)

Country Link
AU (1) AU5962694A (en)
WO (1) WO1994016065A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU684631B2 (en) * 1994-03-31 1997-12-18 Diacrin, Inc. Improved methods for transplantation using modified cells and T cell inhibitory agents

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6093699A (en) * 1987-07-09 2000-07-25 The University Of Manitoba Method for gene therapy involving suppression of an immune response
WO1995006744A2 (en) * 1993-09-03 1995-03-09 Chiron Viagene, Inc. Methods of suppressing immune response by gene therapy
CA2158933A1 (en) * 1993-09-03 1995-03-09 John F. Warner Methods of suppressing graft rejection
US6451571B1 (en) 1994-05-02 2002-09-17 University Of Washington Thymidine kinase mutants
US6156306A (en) * 1994-08-17 2000-12-05 Albert Einstein College Of Medicine Of Yeshiva University Pancreatic β-cells for allogeneic transplantation without immunosuppression
FR2730411B1 (en) * 1995-02-14 1997-03-28 Centre Nat Rech Scient DRUG ASSOCIATION USEFUL FOR IN VIVO TRANSFECTION AND EXPRESSION OF EXOGENES
AU712415B2 (en) * 1995-04-04 1999-11-04 Cell Genesys, Inc. Transplantation of genetically modified cells having low levels of class I MHC proteins on the cell surface
US7485293B1 (en) 1999-02-18 2009-02-03 Faustman Denise L Method for inhibiting transplant rejection

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2093248T3 (en) * 1990-12-04 1996-12-16 Univ Texas METHODS AND COMPOSITIONS FOR THE SUPPRESSION OF THE TRANSFORMATION MEDIATED BY THE NEU.

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU684631B2 (en) * 1994-03-31 1997-12-18 Diacrin, Inc. Improved methods for transplantation using modified cells and T cell inhibitory agents

Also Published As

Publication number Publication date
WO1994016065A1 (en) 1994-07-21

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