AU5737696A - Nucleic acids for treating obesity - Google Patents
Nucleic acids for treating obesityInfo
- Publication number
- AU5737696A AU5737696A AU57376/96A AU5737696A AU5737696A AU 5737696 A AU5737696 A AU 5737696A AU 57376/96 A AU57376/96 A AU 57376/96A AU 5737696 A AU5737696 A AU 5737696A AU 5737696 A AU5737696 A AU 5737696A
- Authority
- AU
- Australia
- Prior art keywords
- nucleic acids
- treating obesity
- obesity
- treating
- nucleic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 208000008589 Obesity Diseases 0.000 title 1
- 150000007523 nucleic acids Chemical class 0.000 title 1
- 102000039446 nucleic acids Human genes 0.000 title 1
- 108020004707 nucleic acids Proteins 0.000 title 1
- 235000020824 obesity Nutrition 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/5759—Products of obesity genes, e.g. leptin, obese (OB), tub, fat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/43504—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates
- C07K14/43563—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from invertebrates from insects
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2799/00—Uses of viruses
- C12N2799/02—Uses of viruses as vector
- C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
- C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Child & Adolescent Psychology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Insects & Arthropods (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US43783495A | 1995-05-08 | 1995-05-08 | |
US437834 | 1995-05-08 | ||
PCT/US1996/006609 WO1996035787A1 (en) | 1995-05-08 | 1996-05-08 | Nucleic acids for treating obesity |
Publications (1)
Publication Number | Publication Date |
---|---|
AU5737696A true AU5737696A (en) | 1996-11-29 |
Family
ID=23738095
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU57376/96A Abandoned AU5737696A (en) | 1995-05-08 | 1996-05-08 | Nucleic acids for treating obesity |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0826045A1 (en) |
JP (1) | JP2000507081A (en) |
AU (1) | AU5737696A (en) |
CA (1) | CA2218529A1 (en) |
WO (1) | WO1996035787A1 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU743161B2 (en) * | 1996-06-04 | 2002-01-17 | Scripps Research Institute, The | Diagnostic and therapeutic methods related to regulating energy mobilization with OB protein and OB antibodies |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6001968A (en) * | 1994-08-17 | 1999-12-14 | The Rockefeller University | OB polypeptides, modified forms and compositions |
US6429290B1 (en) | 1994-08-17 | 2002-08-06 | The Rockefeller University | OB polypeptides, modified forms and derivatives |
GB9511935D0 (en) * | 1995-06-13 | 1995-08-09 | Smithkline Beecham Plc | Novel compound |
US6482927B1 (en) | 1995-11-27 | 2002-11-19 | Millennium Pharmaceuticals, Inc. | Chimeric proteins comprising the extracellular domain of murine Ob receptor |
US7074397B1 (en) | 1996-01-08 | 2006-07-11 | Genentech, Inc. | Method for enhancing proliferation or differentiation of a cell using ob protein |
DE69734443T2 (en) * | 1996-01-08 | 2006-07-13 | Genentech, Inc., South San Francisco | OB RECEPTOR AND LIGANDS |
US20050019325A1 (en) | 1996-01-08 | 2005-01-27 | Carter Paul J. | WSX receptor agonist antibodies |
US7148004B1 (en) | 1997-01-16 | 2006-12-12 | The Rockefeller University | Oligonucleotides of the OB-R isoforms and methods of diagnosing body weight |
US7084252B1 (en) | 1996-01-16 | 2006-08-01 | The Rockefeller University | DB, the receptor for leptin |
US7063958B1 (en) * | 1996-01-16 | 2006-06-20 | The Rockefeller University | Nucleic acids db, the receptor for leptin |
US5831017A (en) * | 1996-01-25 | 1998-11-03 | Eli Lilly And Company | Obesity protein analog compounds and formulations thereof |
US7619079B2 (en) | 1996-02-14 | 2009-11-17 | The Rockefeller University | Db, the receptor for leptin, nucleic acids encoding the receptor, and uses thereof |
US6281346B1 (en) | 1996-03-22 | 2001-08-28 | Merck & Co., Inc. | Rat ob-receptors and nucleotides encoding them |
US6258944B1 (en) | 1996-05-06 | 2001-07-10 | Merck & Co., Inc. | OB receptor isoforms and nucleic acids encoding them |
US7067472B1 (en) | 1996-06-04 | 2006-06-27 | The Scripps Research Institute | Diagnostic and therapeutic methods related to regulating energy mobilization with OB protein and OB antibodies |
CA2258755A1 (en) * | 1996-06-20 | 1997-12-24 | Merck & Co., Inc. | Gene therapy for obesity |
CA2258504A1 (en) * | 1996-06-20 | 1997-12-24 | Merck & Co., Inc. | Gene therapy for obesity |
US6001816A (en) * | 1996-06-20 | 1999-12-14 | Merck & Co., Inc. | Gene therapy for leptin deficiency |
WO1998024881A1 (en) | 1996-12-02 | 1998-06-11 | Merck & Co., Inc. | Mutant ob receptors and nucleotides encoding them |
CA2281888A1 (en) * | 1997-02-25 | 1998-08-27 | Eli Lilly And Company | Treatment of infertility with leptin receptor ligands |
US6420339B1 (en) | 1998-10-14 | 2002-07-16 | Amgen Inc. | Site-directed dual pegylation of proteins for improved bioactivity and biocompatibility |
ATA162699A (en) * | 1999-09-23 | 2002-08-15 | Vitateq Biotechnology Gmbh | METHOD FOR DETERMINING THE FERTILITY OF MAMMALS, ESPECIALLY PEOPLE |
AU7699900A (en) * | 1999-10-01 | 2001-05-10 | Eli Lilly And Company | A novel human leptin homolog |
PL214862B1 (en) | 2001-10-22 | 2013-09-30 | Amgen | Use of leptin for treating human lipoatrophy and method of determining predisposition to said treatment |
US7629315B2 (en) | 2005-03-09 | 2009-12-08 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Compositions for blocking the inhibitory effect of human CRP on human leptin |
US20120071401A1 (en) | 2009-04-10 | 2012-03-22 | Amylin Pharamaceuticals, Inc. | Amylin agonist compounds for estrogen-deficient mammals |
DK3241558T3 (en) | 2010-09-28 | 2021-04-26 | Aegerion Pharmaceuticals Inc | HIGH RESOLUTION LEPTINES |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6309853B1 (en) * | 1994-08-17 | 2001-10-30 | The Rockfeller University | Modulators of body weight, corresponding nucleic acids and proteins, and diagnostic and therapeutic uses thereof |
-
1996
- 1996-05-08 AU AU57376/96A patent/AU5737696A/en not_active Abandoned
- 1996-05-08 JP JP8534257A patent/JP2000507081A/en active Pending
- 1996-05-08 CA CA002218529A patent/CA2218529A1/en not_active Abandoned
- 1996-05-08 WO PCT/US1996/006609 patent/WO1996035787A1/en not_active Application Discontinuation
- 1996-05-08 EP EP96915649A patent/EP0826045A1/en not_active Withdrawn
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU743161B2 (en) * | 1996-06-04 | 2002-01-17 | Scripps Research Institute, The | Diagnostic and therapeutic methods related to regulating energy mobilization with OB protein and OB antibodies |
Also Published As
Publication number | Publication date |
---|---|
CA2218529A1 (en) | 1996-11-14 |
JP2000507081A (en) | 2000-06-13 |
WO1996035787A1 (en) | 1996-11-14 |
EP0826045A1 (en) | 1998-03-04 |
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