AU560330B2 - Substituted l-alanyl antihypertensive - Google Patents

Substituted l-alanyl antihypertensive

Info

Publication number: AU560330B2
Authority: AU; Australia
Prior art keywords: alanyl; antihypertensive; substituted; therefrom; hydroxyamino
Prior art date: 1983-01-12
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

AU23254/84A

Other languages

English (en)

Other versions

AU2325484A (en

Inventor

Fu-Chih Huang

Howard Jones

Clara J. Lin

Bernard Loev

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

USV Pharmaceutical Corp

Original Assignee

USV Pharmaceutical Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-01-12

Filing date

1984-01-12

Publication date

1987-04-02

1984-01-12 Application filed by USV Pharmaceutical Corp filed Critical USV Pharmaceutical Corp

1984-07-19 Publication of AU2325484A publication Critical patent/AU2325484A/en

1987-04-02 Application granted granted Critical

1987-04-02 Publication of AU560330B2 publication Critical patent/AU560330B2/en

2004-01-12 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

125000003412 L-alanyl group Chemical group [H]N([H])[C@@](C([H])([H])[H])(C(=O)[*])[H] 0.000 title 1
230000003276 anti-hypertensive effect Effects 0.000 title 1
206010020772 Hypertension Diseases 0.000 abstract 1
125000003545 alkoxy group Chemical group 0.000 abstract 1
125000004104 aryloxy group Chemical group 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
125000002349 hydroxyamino group Chemical group [H]ON([H])[*] 0.000 abstract 1
239000000825 pharmaceutical preparation Substances 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
- C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/80—Antihypertensive peptides

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biophysics (AREA)
Biochemistry (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Public Health (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Heart & Thoracic Surgery (AREA)
Cardiology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pharmacology & Pharmacy (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Peptides Or Proteins (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Steroid Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Stereophonic System (AREA)
Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
Indole Compounds (AREA)
Magnetic Resonance Imaging Apparatus (AREA)

AU23254/84A 1983-01-12 1984-01-12 Substituted l-alanyl antihypertensive Expired - Fee Related AU560330B2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US457611		1983-01-12
US06/457,611 US4496541A (en)	1983-01-12	1983-01-12	Compounds for treating hypertension

Publications (2)

Publication Number	Publication Date
AU2325484A AU2325484A (en)	1984-07-19
AU560330B2 true AU560330B2 (en)	1987-04-02

Family

ID=23817424

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
AU23254/84A Expired - Fee Related AU560330B2 (en)	1983-01-12	1984-01-12	Substituted l-alanyl antihypertensive

Country Status (16)

Country	Link
US (1)	US4496541A (de)
EP (1)	EP0114067B1 (de)
JP (1)	JPS59130844A (de)
KR (1)	KR840007713A (de)
AT (1)	ATE26841T1 (de)
AU (1)	AU560330B2 (de)
CA (1)	CA1257749A (de)
DE (1)	DE3463385D1 (de)
DK (1)	DK13484A (de)
ES (1)	ES528816A0 (de)
FI (1)	FI85012C (de)
IE (1)	IE56586B1 (de)
IL (1)	IL70676A (de)
NO (1)	NO840102L (de)
NZ (1)	NZ206826A (de)
ZA (1)	ZA84262B (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4686295A (en) *	1982-03-10	1987-08-11	Usv Pharmaceutical Corporation	N-carboxy anhydride intermediates
JPS6248696A (ja) *	1985-08-27	1987-03-03	Kanegafuchi Chem Ind Co Ltd	Ｎ−〔１（ｓ）−エトキシカルボニル−３−フエニルプロピル〕−ｌ−アラニル−ｌ−プロリンの製造法
SI9200213A (en) *	1992-09-16	1994-03-31	Krka	Process for preparing alkyl-l-alanil-l-proline derivates
US6262274B1 (en) *	2000-10-13	2001-07-17	Everlight Usa, Inc.	Process for preparing N-[1-(S)-ethyoxycarbonyl-3-phenylpropyl]-L-ananine N-carboxyanhydride
FR2815962B1 (fr) *	2000-10-30	2003-03-07	Isochem Sa	Procede de preparation des n-carboxyanhydrides
JP2008545006A (ja) *	2005-07-05	2008-12-11	シプラ・リミテッド	Ａｃｅ阻害剤の合成方法
US7960558B2 (en)	2006-05-12	2011-06-14	Egis Gyogyszergyar Nyilvanosan Mukodo Reszvenytarsasag	Pharmaceutical intermediate for synthesizing ACE inhibitors and the use thereof
EP2216949B1 (de) *	2008-04-30	2015-04-22	B & Plus K.K.	Regler für ein-/ausgangssignale
WO2010109590A1 (ja) *	2009-03-24	2010-09-30	株式会社ビー・アンド・プラス	入出力信号制御装置およびこれを用いた入出力信号制御システム

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR1904M (fr) *	1962-03-01	1963-07-08	Merck & Co Inc	Médicament a base d'acide n-acyl-hydroxyamino-acétique pour le traitement des tumeurs.
AT293358B (de) *	1968-03-30	1971-10-11	Richter Gedeon Vegyeszet	Verfahren zur Herstellung von neuen N-Acyl-hydroxylaminderivaten
JPS4843726A (de) *	1971-10-05	1973-06-23
US4098903A (en) *	1976-06-01	1978-07-04	Research Corporation	Anti-hypertensive compounds
IL58849A (en) *	1978-12-11	1983-03-31	Merck & Co Inc	Carboxyalkyl dipeptides and derivatives thereof,their preparation and pharmaceutical compositions containing them
US4820729A (en) *	1981-03-30	1989-04-11	Rorer Pharmaceutical Corporation	N-substituted-amido-amino acids

1983
- 1983-01-12 US US06/457,611 patent/US4496541A/en not_active Expired - Fee Related
1984
- 1984-01-11 JP JP59002110A patent/JPS59130844A/ja active Pending
- 1984-01-12 NO NO840102A patent/NO840102L/no unknown
- 1984-01-12 IL IL70676A patent/IL70676A/xx not_active IP Right Cessation
- 1984-01-12 DK DK13484A patent/DK13484A/da not_active Application Discontinuation
- 1984-01-12 FI FI840109A patent/FI85012C/fi not_active IP Right Cessation
- 1984-01-12 ZA ZA84262A patent/ZA84262B/xx unknown
- 1984-01-12 CA CA000445192A patent/CA1257749A/en not_active Expired
- 1984-01-12 IE IE54/84A patent/IE56586B1/en not_active IP Right Cessation
- 1984-01-12 NZ NZ206826A patent/NZ206826A/en unknown
- 1984-01-12 EP EP84100300A patent/EP0114067B1/de not_active Expired
- 1984-01-12 DE DE8484100300T patent/DE3463385D1/de not_active Expired
- 1984-01-12 ES ES528816A patent/ES528816A0/es active Granted
- 1984-01-12 KR KR1019840000106A patent/KR840007713A/ko not_active Application Discontinuation
- 1984-01-12 AT AT84100300T patent/ATE26841T1/de not_active IP Right Cessation
- 1984-01-12 AU AU23254/84A patent/AU560330B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
FI85012C (fi)	1992-02-25
KR840007713A (ko)	1984-12-10
EP0114067A1 (de)	1984-07-25
FI840109A (fi)	1984-07-13
ZA84262B (en)	1984-08-29
ATE26841T1 (de)	1987-05-15
NO840102L (no)	1984-07-13
DK13484D0 (da)	1984-01-12
IE840054L (en)	1984-07-12
NZ206826A (en)	1986-03-14
ES8504109A1 (es)	1985-05-01
AU2325484A (en)	1984-07-19
FI85012B (fi)	1991-11-15
CA1257749A (en)	1989-07-18
ES528816A0 (es)	1985-05-01
DK13484A (da)	1984-07-13
IE56586B1 (en)	1991-10-09
IL70676A (en)	1988-09-30
EP0114067B1 (de)	1987-04-29
US4496541A (en)	1985-01-29
DE3463385D1 (en)	1987-06-04
JPS59130844A (ja)	1984-07-27
IL70676A0 (en)	1984-04-30
FI840109A0 (fi)	1984-01-12

Publication	Publication Date	Title
AU4783685A (en)	1986-04-24	Diarylacetylenes, their preparation and their use
MY149862A (en)	2013-10-31	Compounds useful to treat retroviral infections
EA200000723A1 (ru)	2001-04-23	Производные 2-(пурин-9-ил)-тетрагидрофуран-3,4-диола
IL104154A0 (en)	1993-05-13	Saccharin derivatives,their preparation and pharmaceutical compositions containing them
AU7095587A (en)	1987-10-08	1,4-diazepines
AU560330B2 (en)	1987-04-02	Substituted l-alanyl antihypertensive
ES8706654A1 (es)	1987-07-01	Un procedimiento para la preparacion de nuevos derivados de benzotiazina
AU693283B2 (en)	1998-06-25	Acrylamide derivatives and process for producing the same
NO952743L (no)	1996-01-15	Ny benzotiadiazinforbindelse, dens fremstilling og farmasöytiske preparater
NZ308398A (en)	1999-06-29	2-amino benzoxazin-4-one derivatives and medicaments
PH25034A (en)	1991-01-28	Process for the preparation of imidazoquinazoline compounds and intermediate for use in said process
ATE87662T1 (de)	1993-04-15	Antidiabetikaverbindungen.
ES8704875A1 (es)	1987-05-01	Procedimiento de producir compuestos para tratar la hiper- tension
BG103260A (en)	2000-01-31	The application of 1-hydroxy-2-pyridons for the treatment of seborrheic dermatitis
EP0127124A3 (de)	1987-04-08	Verbindungen zur Behandlung von hohem Blutdruck
EP0112511A3 (en)	1985-11-13	New compounds, pharmaceutical preparations containing same and process for their preparation
FR2421894A1 (fr)	1979-11-02	Nouvelles 2,3-dihydro-4h-1-benzopyranne-4-one-o-carbamoyloximes utiles notamment comme inhibiteurs de secretion gastrique
IE791438L (en)	1980-01-31	Oxadiazolotriazines
EP0153755A3 (de)	1986-04-16	Verbindungen zur Behandlung von hohem Blutdruck
DE3461189D1 (en)	1986-12-11	New 3-alkylthio-2-o-carbamoyl-propane-1.2-diol-1-o-phosphocholines, and processes for their preparation
FR2401158A1 (fr)	1979-03-23	Nouvelles 3-(4-chromanylamino)-2-oxazolidinones utiles notamment comme inhibiteurs de la secretion gastrique
PT82535B (en)	1987-09-23	Pharmacologically active propionylanilides
SU1269465A1 (ru)	1996-04-10	Способ получения 2-анилино-7-гидрокси-6н-1,3,4-тиадиазепинов