AU5503399A - Medicaments containing bisphosphonic acids and derivatives thereof which are provided for preventing and treating autoimmune diseases and allergies - Google Patents

Medicaments containing bisphosphonic acids and derivatives thereof which are provided for preventing and treating autoimmune diseases and allergies

Info

Publication number
AU5503399A
AU5503399A AU55033/99A AU5503399A AU5503399A AU 5503399 A AU5503399 A AU 5503399A AU 55033/99 A AU55033/99 A AU 55033/99A AU 5503399 A AU5503399 A AU 5503399A AU 5503399 A AU5503399 A AU 5503399A
Authority
AU
Australia
Prior art keywords
acid
derivatives
bisphosphonic
autoimmune diseases
bisphosphonic acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU55033/99A
Other versions
AU740605B2 (en
Inventor
Hassan Jomaa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bioagency AG
Original Assignee
Bioagency AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioagency AG filed Critical Bioagency AG
Publication of AU5503399A publication Critical patent/AU5503399A/en
Application granted granted Critical
Publication of AU740605B2 publication Critical patent/AU740605B2/en
Assigned to JOMAA PHARMAKA GMBH reassignment JOMAA PHARMAKA GMBH Alteration of Name(s) in Register under S187 Assignors: JOMAA, HASSAN
Assigned to BIOAGENCY AG reassignment BIOAGENCY AG Alteration of Name(s) in Register under S187 Assignors: JOMAA PHARMAKA GMBH
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/662—Phosphorus acids or esters thereof having P—C bonds, e.g. foscarnet, trichlorfon
    • A61K31/663—Compounds having two or more phosphorus acid groups or esters thereof, e.g. clodronic acid, pamidronic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents

Abstract

The invention relates to the use of bisphosphonic acids and the derivatives thereof for producing medicaments for preventing and treating autoimmune diseases or allergies combined with the autoantigens specifically used for treating the respective autoimmune disease or combined with the allergens specifically used for treating the respective allergy. Some examples of the bisphosphonic acids or derivatives thereof which are used according to the invention include amino-hydroxy-methylidene-bisphosphonic acid (AMP), 2-amino-1-hydroxyethylidene-1,1-bisphosphonic acid (AEP), pamidronic acid, alendronic acid, 6-amino-1-hydroxyhexylidene-1,1-bisphosphonic acid (AHP), amidinomethylene-bisphosphonic acid (AIMP), ibandronic acid, risedronic acid, zoledronic acid, cimadronic acid, and tiludronic acid. Some examples of autoimmune diseases in which bisphosphonic acids or the derivatives thereof can be used include rheumatoid arthritis, severe myasthenia, diabetes mellitus, uveitis, and scleroderma. The bisphosphonic acids or the derivatives thereof and the autoantigens or allergens can be applied simultaneously or in succession. The preparations of the combinations can be used in solid form, as ointments, as solutions or as sprays.
AU55033/99A 1998-06-26 1999-06-24 Medicaments containing bisphosphonic acids and derivatives thereof which are provided for preventing and treating autoimmune diseases and allergies Ceased AU740605B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19828450A DE19828450A1 (en) 1998-06-26 1998-06-26 Use of bisphosphonic acid compounds and autoantigens or allergens
DE19828450 1998-06-26
PCT/DE1999/001844 WO2000000182A2 (en) 1998-06-26 1999-06-24 Medicaments containing bisphosphonic acids and derivatives thereof which are provided for preventing and treating autoimmune diseases and allergies

Publications (2)

Publication Number Publication Date
AU5503399A true AU5503399A (en) 2000-01-17
AU740605B2 AU740605B2 (en) 2001-11-08

Family

ID=7872064

Family Applications (1)

Application Number Title Priority Date Filing Date
AU55033/99A Ceased AU740605B2 (en) 1998-06-26 1999-06-24 Medicaments containing bisphosphonic acids and derivatives thereof which are provided for preventing and treating autoimmune diseases and allergies

Country Status (24)

Country Link
EP (1) EP1089761B1 (en)
JP (1) JP2002519319A (en)
KR (1) KR20010053211A (en)
AT (1) ATE224734T1 (en)
AU (1) AU740605B2 (en)
CA (1) CA2334711C (en)
DE (2) DE19828450A1 (en)
DK (1) DK1089761T3 (en)
EA (1) EA200100080A1 (en)
EE (1) EE200000756A (en)
ES (1) ES2184496T3 (en)
HR (1) HRP20000820A2 (en)
HU (1) HUP0102873A3 (en)
ID (1) ID27515A (en)
IL (1) IL139966A0 (en)
IS (1) IS5748A (en)
MX (1) MXPA00012338A (en)
NO (1) NO20006572L (en)
NZ (1) NZ509505A (en)
PL (1) PL345287A1 (en)
PT (1) PT1089761E (en)
SK (1) SK19602000A3 (en)
TR (1) TR200003821T2 (en)
WO (1) WO2000000182A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2356262A1 (en) 1998-12-23 2000-07-06 Jomaa Pharmaka Gmbh Use of bisphosphonates for the prevention and treatment of infectious processes
WO2000038693A1 (en) * 1998-12-25 2000-07-06 Toray Industries, Inc. Interleukin-6 production inhibitors
EP1392325B1 (en) * 2001-05-02 2006-06-21 Novartis AG Method of administration of bisphosphonates by inhalation in the treatment or prevention of bone resorption and osteoporosis
PT1408984E (en) 2001-07-20 2008-12-26 Bioagency Ag Organo-phosphorous compounds for activating gamma/delta t cells
GB0307989D0 (en) * 2003-04-07 2003-05-14 Mcewen Lab Ltd Therapeutic composition
EP1713489B1 (en) * 2004-08-23 2011-01-19 Teva Pharmaceutical Industries Ltd Crystalline form of ibandronate sodium and processes for preparation thereof
EP1931326A4 (en) * 2005-09-12 2009-12-16 Reddys Lab Ltd Dr Crystalline trihydrate of zoledronic acid

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2114946T3 (en) * 1991-09-05 1998-06-16 Toray Industries DERIVATIVE OF METHANODIPHOSPHONIC ACID, ITS PRODUCTION AND MEDICINAL USE.
WO1996022790A1 (en) * 1995-01-23 1996-08-01 Xenotech Incorporated Composition to ameliorate osteolysis and metastasis

Also Published As

Publication number Publication date
ATE224734T1 (en) 2002-10-15
KR20010053211A (en) 2001-06-25
DE19828450A1 (en) 1999-12-30
WO2000000182A2 (en) 2000-01-06
HUP0102873A3 (en) 2002-04-29
AU740605B2 (en) 2001-11-08
PL345287A1 (en) 2001-12-03
TR200003821T2 (en) 2001-06-21
DK1089761T3 (en) 2003-02-03
EA200100080A1 (en) 2001-06-25
NO20006572L (en) 2001-02-21
HRP20000820A2 (en) 2001-12-31
HUP0102873A2 (en) 2001-12-28
NZ509505A (en) 2002-11-26
CA2334711A1 (en) 2000-01-06
NO20006572D0 (en) 2000-12-21
PT1089761E (en) 2003-02-28
CA2334711C (en) 2006-12-05
EP1089761B1 (en) 2002-09-25
MXPA00012338A (en) 2003-04-25
EP1089761A2 (en) 2001-04-11
DE59902856D1 (en) 2002-10-31
IL139966A0 (en) 2002-02-10
JP2002519319A (en) 2002-07-02
SK19602000A3 (en) 2001-07-10
ID27515A (en) 2001-04-12
IS5748A (en) 2000-12-01
ES2184496T3 (en) 2003-04-01
EE200000756A (en) 2002-04-15
WO2000000182A3 (en) 2000-03-30

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Legal Events

Date Code Title Description
FGA Letters patent sealed or granted (standard patent)
PC Assignment registered

Owner name: JOMAA PHARMAKA GMBH

Free format text: FORMER OWNER WAS: HASSAN JOMAA

PC Assignment registered

Owner name: BIOAGENCY AG

Free format text: FORMER OWNER WAS: JOMAA PHARMAKA GMBH