AU511711B2 - 6-Oxo and 5, 6-Dihalo prostaglandin analogues - Google Patents
6-Oxo and 5, 6-Dihalo prostaglandin analoguesInfo
- Publication number
- AU511711B2 AU511711B2 AU31067/77A AU3106777A AU511711B2 AU 511711 B2 AU511711 B2 AU 511711B2 AU 31067/77 A AU31067/77 A AU 31067/77A AU 3106777 A AU3106777 A AU 3106777A AU 511711 B2 AU511711 B2 AU 511711B2
- Authority
- AU
- Australia
- Prior art keywords
- dihalo
- oxo
- prostaglandin analogues
- prostaglandin
- analogues
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940006138 antiglaucoma drug and miotics prostaglandin analogues Drugs 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
- C07D307/935—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans
- C07D307/937—Not further condensed cyclopenta [b] furans or hydrogenated cyclopenta [b] furans with hydrocarbon or substituted hydrocarbon radicals directly attached in position 2, e.g. prostacyclins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
- C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
- C07C405/0041—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing nitrogen
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US75567476A | 1976-12-30 | 1976-12-30 | |
US75567576A | 1976-12-30 | 1976-12-30 | |
USUS755,674 | 1976-12-30 | ||
USUS755,675 | 1976-12-30 | ||
US05/829,679 US4205178A (en) | 1976-12-30 | 1977-09-02 | 6-Keto prostaglandin E-type compounds |
USUS829.679 | 1977-09-02 | ||
US05/829,678 US4124601A (en) | 1976-12-30 | 1977-09-02 | Certain 5-halo-6,9α-epoxy-14-bromo(or chloro)-PGF1 compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
AU3106777A AU3106777A (en) | 1979-06-07 |
AU511711B2 true AU511711B2 (en) | 1980-09-04 |
Family
ID=27505671
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU31067/77A Expired AU511711B2 (en) | 1976-12-30 | 1977-11-30 | 6-Oxo and 5, 6-Dihalo prostaglandin analogues |
Country Status (7)
Country | Link |
---|---|
JP (1) | JPS5811438B2 (fr) |
AU (1) | AU511711B2 (fr) |
BE (1) | BE862547A (fr) |
DE (1) | DE2753986C2 (fr) |
FR (1) | FR2376134A1 (fr) |
GB (1) | GB1565604A (fr) |
NL (1) | NL190600C (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU620543B2 (en) * | 1987-03-13 | 1992-02-20 | Schering Aktiengesellschaft | 6-oxoprostaglandin-e derivatives, process for their production and their pharmaceutical application |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL51189A (en) * | 1976-02-04 | 1985-08-30 | Upjohn Co | Prostaglandin analogs |
FI71138C (fi) * | 1976-12-31 | 1986-11-24 | Erba Farmitalia | Foerfarande foer framstaellning av terapeutiskt aktiva bisykliska prostaglandiner |
IT1098350B (it) * | 1977-07-28 | 1985-09-07 | Upjohn Co | Derivati prostaglandinici |
JPS6022710B2 (ja) * | 1977-09-16 | 1985-06-03 | 小野薬品工業株式会社 | プロスタグランジン類似化合物 |
IT1089247B (it) * | 1977-12-30 | 1985-06-18 | Erba Carlo Spa | 5-6-di idro-prostaciclina derivati |
DE2834249A1 (de) * | 1978-08-04 | 1980-02-28 | Hoechst Ag | Neue prostaglandinderivate in der delta 2-11-desoxy-pgf tief 2 bzw. pge tief 2 -reihe |
DE2834248A1 (de) * | 1978-08-04 | 1980-02-28 | Hoechst Ag | Neue prostaglandinderivate in der delta 2-pgf tief 2 und delta 2-pge tief 2 -reihe |
DE2913856A1 (de) * | 1979-04-06 | 1980-10-23 | Hoechst Ag | Neue prostaglandinderivate in der 6-keto-pge tief 1 -reihe |
DE2946116A1 (de) * | 1979-11-15 | 1981-05-27 | Hoechst Ag, 6000 Frankfurt | Neue prostaglandinderivate in der 6-keto-pga(pfeil abwaerts)1 -reihe(pfeil abwaerts) |
DE3315356A1 (de) * | 1982-04-30 | 1983-11-17 | Ono Pharmaceutical Co. Ltd., Osaka | Verwendung von prostaglandinanalogen |
JPS5920267A (ja) * | 1982-07-22 | 1984-02-01 | Ono Pharmaceut Co Ltd | プロスタグランジンe↓1類似化合物 |
JPS62277352A (ja) * | 1986-01-30 | 1987-12-02 | Ono Pharmaceut Co Ltd | 新規な6−ケト−プロスタグランジンe1誘導体、それらの製造方法およびそれらを有効成分として含有する細胞障害治療剤 |
US4981872A (en) * | 1987-01-19 | 1991-01-01 | Sankyo Company Limited | Prostaglandin derivatives, their preparation and their therapeutic use |
DE3704825A1 (de) * | 1987-02-16 | 1988-08-25 | Froelich Juergen | Prostaglandin e1-derivate als pharmazeutische wirkstoffe und diese verbindungen enthaltende arzneimittel insbesondere zur transkutanen anwendung |
US5219885A (en) * | 1987-02-16 | 1993-06-15 | Froelich Juergen | Prostaglandin E1 derivatives as pharmaceutically active agents, and pharmaceutical compositions containing these compounds, especially for transcutaneous administration |
JPH053100Y2 (fr) * | 1988-04-28 | 1993-01-26 | ||
KR20020016938A (ko) | 1999-08-05 | 2002-03-06 | 야스이 쇼사꾸 | 함질소화합물을 유효성분으로 하는 신경장해개선제 |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL51189A (en) * | 1976-02-04 | 1985-08-30 | Upjohn Co | Prostaglandin analogs |
-
1977
- 1977-11-30 AU AU31067/77A patent/AU511711B2/en not_active Expired
- 1977-12-03 DE DE2753986A patent/DE2753986C2/de not_active Expired
- 1977-12-12 GB GB51701/77A patent/GB1565604A/en not_active Expired
- 1977-12-21 NL NL7714172A patent/NL190600C/xx not_active IP Right Cessation
- 1977-12-26 JP JP52155770A patent/JPS5811438B2/ja not_active Expired
- 1977-12-29 FR FR7739685A patent/FR2376134A1/fr active Granted
- 1977-12-30 BE BE184030A patent/BE862547A/fr not_active IP Right Cessation
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU620543B2 (en) * | 1987-03-13 | 1992-02-20 | Schering Aktiengesellschaft | 6-oxoprostaglandin-e derivatives, process for their production and their pharmaceutical application |
Also Published As
Publication number | Publication date |
---|---|
FR2376134B1 (fr) | 1985-04-12 |
DE2753986A1 (de) | 1978-07-06 |
JPS5811438B2 (ja) | 1983-03-02 |
JPS5384942A (en) | 1978-07-26 |
AU3106777A (en) | 1979-06-07 |
NL190600B (nl) | 1993-12-16 |
DE2753986C2 (de) | 1986-05-07 |
FR2376134A1 (fr) | 1978-07-28 |
NL7714172A (nl) | 1978-07-04 |
NL190600C (nl) | 1994-05-16 |
BE862547A (fr) | 1978-06-30 |
GB1565604A (en) | 1980-04-23 |
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