AU4822500A - Novel highly lipophilic camptothecin analogs - Google Patents

Novel highly lipophilic camptothecin analogs

Info

Publication number
AU4822500A
AU4822500A AU48225/00A AU4822500A AU4822500A AU 4822500 A AU4822500 A AU 4822500A AU 48225/00 A AU48225/00 A AU 48225/00A AU 4822500 A AU4822500 A AU 4822500A AU 4822500 A AU4822500 A AU 4822500A
Authority
AU
Australia
Prior art keywords
highly lipophilic
camptothecin analogs
novel highly
lipophilic camptothecin
novel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU48225/00A
Inventor
Xinghai Chen
Frederick H. Hausheer
Qiuli Huang
Harry Kochat
Seetharamulu Peddaiaghari
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
BioNumerik Pharmaceuticals Inc
Original Assignee
BioNumerik Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by BioNumerik Pharmaceuticals Inc filed Critical BioNumerik Pharmaceuticals Inc
Publication of AU4822500A publication Critical patent/AU4822500A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/0803—Compounds with Si-C or Si-Si linkages
    • C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
    • C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AU48225/00A 1999-05-04 2000-05-04 Novel highly lipophilic camptothecin analogs Abandoned AU4822500A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13241499P 1999-05-04 1999-05-04
US60132414 1999-05-04
PCT/US2000/012318 WO2000066127A1 (en) 1999-05-04 2000-05-04 Novel highly lipophilic camptothecin analogs

Publications (1)

Publication Number Publication Date
AU4822500A true AU4822500A (en) 2000-11-17

Family

ID=22453945

Family Applications (1)

Application Number Title Priority Date Filing Date
AU48225/00A Abandoned AU4822500A (en) 1999-05-04 2000-05-04 Novel highly lipophilic camptothecin analogs

Country Status (2)

Country Link
AU (1) AU4822500A (en)
WO (1) WO2000066127A1 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6350756B1 (en) 2001-01-18 2002-02-26 California Pacific Medical Center Camptothecin derivatives
US6855720B2 (en) 2001-03-01 2005-02-15 California Pacific Medical Center Nitrogen-based camptothecin derivatives
US6403604B1 (en) 2001-03-01 2002-06-11 California Pacific Medical Center Nitrogen-based camptothecin derivatives
AU2003243380A1 (en) 2002-06-03 2003-12-19 California Pacific Medical Center Nitrogen-based homo-camptothecin derivatives
US7875602B2 (en) 2005-10-21 2011-01-25 Sutter West Bay Hospitals Camptothecin derivatives as chemoradiosensitizing agents
ITMI20061475A1 (en) 2006-07-26 2008-01-27 Indena Spa DERIVATIVES OF CAMPTOTECIN WITH ANTITUMORAL ACTIVITY
WO2009051580A1 (en) * 2007-10-16 2009-04-23 Bionumerik Pharmaceuticals, Inc. C7-substituted camptothecin analogs
CA2700904C (en) * 2007-10-16 2014-10-14 Bionumerik Pharmaceuticals, Inc. C10-substituted camptothecin analogs

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9711319B1 (en) * 1996-08-19 2009-08-11 highly lipophilic camptothecin derivatives.
WO1998035940A1 (en) * 1997-02-14 1998-08-20 Bionumerik Pharmaceuticals, Inc. Highly lipophilic camptothecin derivatives
US6057303A (en) * 1998-10-20 2000-05-02 Bionumerik Pharmaceuticals, Inc. Highly lipophilic Camptothecin derivatives

Also Published As

Publication number Publication date
WO2000066127A1 (en) 2000-11-09

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase