AU4665193A - A process for recovering a recombinant protein, in biologically active form, from a solution containing inactive protein - Google Patents

A process for recovering a recombinant protein, in biologically active form, from a solution containing inactive protein

Info

Publication number
AU4665193A
AU4665193A AU46651/93A AU4665193A AU4665193A AU 4665193 A AU4665193 A AU 4665193A AU 46651/93 A AU46651/93 A AU 46651/93A AU 4665193 A AU4665193 A AU 4665193A AU 4665193 A AU4665193 A AU 4665193A
Authority
AU
Australia
Prior art keywords
protein
recovering
solution containing
biologically active
active form
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU46651/93A
Inventor
Eunkyu Lee
Doreen A Svihla
Ren-Der Yang
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Veterinary Inc
Original Assignee
Pitman Moore Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pitman Moore Inc filed Critical Pitman Moore Inc
Publication of AU4665193A publication Critical patent/AU4665193A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/113—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure
    • C07K1/1133—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides without change of the primary structure by redox-reactions involving cystein/cystin side chains
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Endocrinology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AU46651/93A 1992-07-02 1993-07-01 A process for recovering a recombinant protein, in biologically active form, from a solution containing inactive protein Abandoned AU4665193A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US90814692A 1992-07-02 1992-07-02
US908146 1992-07-02
PCT/US1993/006351 WO1994001453A1 (en) 1992-07-02 1993-07-01 A process for recovering a recombinant protein, in biologically active form, from a solution containing inactive protein

Publications (1)

Publication Number Publication Date
AU4665193A true AU4665193A (en) 1994-01-31

Family

ID=25425274

Family Applications (1)

Application Number Title Priority Date Filing Date
AU46651/93A Abandoned AU4665193A (en) 1992-07-02 1993-07-01 A process for recovering a recombinant protein, in biologically active form, from a solution containing inactive protein

Country Status (7)

Country Link
EP (1) EP0650497A1 (en)
CN (1) CN1039330C (en)
AU (1) AU4665193A (en)
PL (1) PL306858A1 (en)
TW (1) TW235965B (en)
WO (1) WO1994001453A1 (en)
ZA (1) ZA934780B (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6753165B1 (en) 1999-01-14 2004-06-22 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
US7153943B2 (en) 1997-07-14 2006-12-26 Bolder Biotechnology, Inc. Derivatives of growth hormone and related proteins, and methods of use thereof
US20080076706A1 (en) 1997-07-14 2008-03-27 Bolder Biotechnology, Inc. Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof
WO1999003887A1 (en) 1997-07-14 1999-01-28 Bolder Biotechnology, Inc. Derivatives of growth hormone and related proteins
US7270809B2 (en) 1997-07-14 2007-09-18 Bolder Biotechnology, Inc. Cysteine variants of alpha interferon-2
WO2000012537A1 (en) * 1998-08-27 2000-03-09 Lg Chemical Limited Process for the preparation of active somatotropin from inclusion bodies
US8288126B2 (en) 1999-01-14 2012-10-16 Bolder Biotechnology, Inc. Methods for making proteins containing free cysteine residues
JP4873818B2 (en) 2000-05-16 2012-02-08 ボルダー バイオテクノロジー， インコーポレイテッド Methods for refolding proteins containing free cysteine residues
EP2102355B1 (en) 2006-12-14 2016-03-02 Bolder Biotechnology, Inc. Long acting proteins and peptides and methods of making and using the same
WO2017019776A1 (en) * 2015-07-27 2017-02-02 Purdue Research Foundation Tandem folding methods to improve protein folding yield
WO2017040363A1 (en) 2015-09-02 2017-03-09 Merck Sharp & Dohme Corp. A process for obtaining insulin with correctly formed disulfide bonds
CN111610324B (en) * 2020-06-06 2022-10-14 北京均大检测科技有限公司 RIPA lysate and preparation method thereof
CN114878728A (en) * 2022-05-06 2022-08-09 浙江大学 Novel antibody peptide pattern detection reduction method

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4931543A (en) * 1987-05-11 1990-06-05 Cetus Corporation Process for recovering microbially produced interleukin-2
EP0301835A1 (en) * 1987-07-29 1989-02-01 Schering Biotech Corporation Purification of human interleukin-4 expressed in Escherichia Coli
JPH01132598A (en) * 1987-10-14 1989-05-25 Pitman Moore Inc Method for promoting production of intramolecular disulfide bond in recominant protein contained in modifier solution
US5064943A (en) * 1988-12-16 1991-11-12 American Cyanamid Company Method for solubilization and naturation of somatotropin
EP0547102B1 (en) * 1990-09-05 1998-07-08 Southern Cross Biotech Pty.Ltd. Solubilization of proteins in active forms

Also Published As

Publication number Publication date
EP0650497A1 (en) 1995-05-03
TW235965B (en) 1994-12-11
ZA934780B (en) 1994-03-17
WO1994001453A1 (en) 1994-01-20
PL306858A1 (en) 1995-04-18
CN1083071A (en) 1994-03-02
CN1039330C (en) 1998-07-29

Similar Documents

Publication Publication Date Title
AU3481689A (en) Nahcolite solution mining process
AU668295B2 (en) N-acyl-N,N',N'-ethylenediaminetriacetic acid derivatives and process for preparing same
AU4665193A (en) A process for recovering a recombinant protein, in biologically active form, from a solution containing inactive protein
HU9402078D0 (en) Phthalazin-1-ones and phtalazin-1-thiones, composhions containing them and process for thei preparation
EP0209041A3 (en) Method of purifying factor viii:c
HUT58764A (en) Process for producing peptides, pharmaceutical compositions containing them and amino-acid intermediates
AU3788189A (en) 3, 9-diphosphaspiroundecanes and process for making3, 9-diphosphaspiroundecanes
EP0644769A4 (en) Biologically active peptides having n-terminal substitutions.
LTIP599A (en) Novel, biologically active eburnamenine derivatives and a process for preparing the same
AU7088394A (en) Biologically active vasopressin analogues
AU7955391A (en) Method for purifying recombinantly-produced proteins
EP0658115A4 (en) Peptide medicaments for treating disease.
GB9114734D0 (en) Process for modifying proteins
AU4521389A (en) Process for purifying blood plasma
EP0816510A4 (en) Process for producing biologically active fused proteins
AU4565189A (en) Pump system for moistener nozzle
AU7548291A (en) Process for purifying polypeptide
AU3400893A (en) New 2,4-thiazolidinedione compounds, process for preparing them and pharmaceutical compositios containing them
GB8816496D0 (en) Process & means for efficient photosynthesis
AU8467591A (en) Catalyst recovery process
AU5538794A (en) Biologically active compounds and process therefor
EP0592881A3 (en) Process for producing optically active gamma-hydroxyketones.
EP0640579A3 (en) Process for producing optically active 2-norbornanone.
AU2961689A (en) Process for concentrating a urea solution
AU5522694A (en) Chrysospermins, active peptides from apiocrea chrysosperma having a pharmacological effect, a process for their preparation and the use thereof