AU4236693A - Chemical synthesis of 2',3'-dideoxynucleoside 5'-(alpha-thio) triphosphates - Google Patents

Chemical synthesis of 2',3'-dideoxynucleoside 5'-(alpha-thio) triphosphates

Info

Publication number
AU4236693A
AU4236693A AU42366/93A AU4236693A AU4236693A AU 4236693 A AU4236693 A AU 4236693A AU 42366/93 A AU42366/93 A AU 42366/93A AU 4236693 A AU4236693 A AU 4236693A AU 4236693 A AU4236693 A AU 4236693A
Authority
AU
Australia
Prior art keywords
dideoxynucleoside
triphosphates
thio
alpha
chemical synthesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU42366/93A
Inventor
Leonid Beigelman
Jasenka Matulic-Adamic
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
United States Biochemical Corp
Original Assignee
United States Biochemical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by United States Biochemical Corp filed Critical United States Biochemical Corp
Publication of AU4236693A publication Critical patent/AU4236693A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
    • C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Saccharide Compounds (AREA)
AU42366/93A 1992-05-13 1993-05-06 Chemical synthesis of 2',3'-dideoxynucleoside 5'-(alpha-thio) triphosphates Abandoned AU4236693A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US88248892A 1992-05-13 1992-05-13
US882488 1992-05-13

Publications (1)

Publication Number Publication Date
AU4236693A true AU4236693A (en) 1993-12-13

Family

ID=25380698

Family Applications (1)

Application Number Title Priority Date Filing Date
AU42366/93A Abandoned AU4236693A (en) 1992-05-13 1993-05-06 Chemical synthesis of 2',3'-dideoxynucleoside 5'-(alpha-thio) triphosphates

Country Status (2)

Country Link
AU (1) AU4236693A (en)
WO (1) WO1993023415A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9504598D0 (en) 1995-03-03 1995-04-26 Imp Cancer Res Tech Method of nucleic acid analysis
GB9620209D0 (en) * 1996-09-27 1996-11-13 Cemu Bioteknik Ab Method of sequencing DNA
GB9626815D0 (en) 1996-12-23 1997-02-12 Cemu Bioteknik Ab Method of sequencing DNA
CN113621011B (en) * 2021-08-17 2023-07-04 上海兆维科技发展有限公司 Process for preparing 2',3' -dideoxynucleoside-5' -O- (alpha-thio) triphosphate

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3336289A (en) * 1965-09-20 1967-08-15 Upjohn Co 9-beta-d-ribofuranosyl-7-deazapurine 5'-phosphate esters

Also Published As

Publication number Publication date
WO1993023415A1 (en) 1993-11-25

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