AU4036389A - High efficiency translation of polycistronic messages in eucaryotic cells - Google Patents

High efficiency translation of polycistronic messages in eucaryotic cells

Info

Publication number
AU4036389A
AU4036389A AU40363/89A AU4036389A AU4036389A AU 4036389 A AU4036389 A AU 4036389A AU 40363/89 A AU40363/89 A AU 40363/89A AU 4036389 A AU4036389 A AU 4036389A AU 4036389 A AU4036389 A AU 4036389A
Authority
AU
Australia
Prior art keywords
high efficiency
eucaryotic cells
polycistronic messages
efficiency translation
translation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU40363/89A
Inventor
Kathleen L. Berkner
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Zymogenetics Inc
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Publication of AU4036389A publication Critical patent/AU4036389A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00—Vectors comprising a special translation-regulating system
    • C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
AU40363/89A 1988-07-29 1989-07-26 High efficiency translation of polycistronic messages in eucaryotic cells Abandoned AU4036389A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22617388A 1988-07-29 1988-07-29
US226173 1999-01-07

Publications (1)

Publication Number Publication Date
AU4036389A true AU4036389A (en) 1990-03-05

Family

ID=22847870

Family Applications (1)

Application Number Title Priority Date Filing Date
AU40363/89A Abandoned AU4036389A (en) 1988-07-29 1989-07-26 High efficiency translation of polycistronic messages in eucaryotic cells

Country Status (4)

Country Link
EP (1) EP0426744A1 (en)
JP (1) JPH04500004A (en)
AU (1) AU4036389A (en)
WO (1) WO1990001550A1 (en)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2173082T3 (en) * 1991-08-07 2002-10-16 W French Anderson RETROVIRAL VECTORS CONTAINING INTERNAL RIBOSOME ENTRY SITES.
US5648235A (en) * 1992-07-03 1997-07-15 Q.B.I. Enterprises Ltd. Method and means for the production of gene products, novel recombinant DNA vectors therefor and kits employing them
DE4228457A1 (en) * 1992-08-27 1994-04-28 Beiersdorf Ag Production of heterodimeric PDGF-AB using a bicistronic vector system in mammalian cells
DE4228458A1 (en) * 1992-08-27 1994-06-01 Beiersdorf Ag Multicistronic expression units and their use
CA2162056A1 (en) * 1993-01-20 1994-11-10 Christian A. Le Guern Retroviral vectors capable of expressing multimeric proteins from multiple translational initiation sites
AU780164B2 (en) * 1994-09-13 2005-03-03 Transgene S.A. Novel implant and novel vector for the treatment of acquired diseases
FR2724320B1 (en) 1994-09-13 1996-12-20 Transgene Sa NEW IMPLANT FOR THE TREATMENT OF ACQUIRED DISEASES
US5518042A (en) * 1994-09-16 1996-05-21 Huyck Licensco, Inc. Papermaker's forming fabric with additional cross machine direction locator and fiber supporting yarns
AT403167B (en) * 1994-11-14 1997-11-25 Immuno Ag SELECTION AND EXPRESSION OF FOREIGN PROTEINS BY MEANS OF A SELECTION-AMPLIFICATION SYSTEM
IL112872A0 (en) * 1995-03-03 1995-06-29 Q B I Enterprises Ltd Novel recombinant dna vectors and kits employing them
DE19514310A1 (en) * 1995-04-18 1996-10-24 Univ Ludwigs Albert Vectors for the transfection of eukaryotic cells, their use and thus transfected target cells
US5990091A (en) * 1997-03-12 1999-11-23 Virogenetics Corporation Vectors having enhanced expression, and methods of making and uses thereof
US6525189B1 (en) * 1999-10-15 2003-02-25 The Mclean Hospital Corporation Multimerized DBH enhancer domains
US7037715B2 (en) 1999-10-15 2006-05-02 The Mclean Hospital Multimerized DBH enhancer domains
WO2003033463A2 (en) 2001-10-19 2003-04-24 The Mclean Hospital Corporation Multimerized enhancer domains for cell-specific expression
WO2013161958A1 (en) 2012-04-27 2013-10-31 日本ケミカルリサーチ株式会社 Novel expression vector

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4713339A (en) * 1983-01-19 1987-12-15 Genentech, Inc. Polycistronic expression vector construction
EP0154576A1 (en) * 1984-02-06 1985-09-11 INTERFERON SCIENCES, INC a Delaware Corporation Hybrid nucleic acid sequences having tandemly arranged genes
JPH0630590B2 (en) * 1985-08-30 1994-04-27 株式会社ヤクルト本社 Complex plasmid vector
WO1987002707A1 (en) * 1985-11-05 1987-05-07 Genetics Institute, Inc. Multiply-amplifiable vectors for high level expression of exogenous dna
AU1187588A (en) * 1987-01-15 1988-08-10 Codon Genetic Engineering Laboratories Tandem gene eukaryotic expression vectors

Also Published As

Publication number Publication date
WO1990001550A1 (en) 1990-02-22
EP0426744A1 (en) 1991-05-15
JPH04500004A (en) 1992-01-09

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