AU3967593A - Method of intraoperatively detecting and locating tumoral tissues - Google Patents

Method of intraoperatively detecting and locating tumoral tissues

Info

Publication number
AU3967593A
AU3967593A AU39675/93A AU3967593A AU3967593A AU 3967593 A AU3967593 A AU 3967593A AU 39675/93 A AU39675/93 A AU 39675/93A AU 3967593 A AU3967593 A AU 3967593A AU 3967593 A AU3967593 A AU 3967593A
Authority
AU
Australia
Prior art keywords
group
peptide
peptide compound
labelled
pro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU39675/93A
Other languages
English (en)
Inventor
Bareld Jan Doedens
Geert Jacob Ensing
Karel Jan Panek
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Medical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Medical Inc filed Critical Mallinckrodt Medical Inc
Publication of AU3967593A publication Critical patent/AU3967593A/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/655Somatostatins
    • C07K14/6555Somatostatins at least 1 amino acid in D-form
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/083Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the peptide being octreotide or a somatostatin-receptor-binding peptide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04Organic compounds
    • A61K51/08Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/088Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins conjugates with carriers being peptides, polyamino acids or proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00Preparations for testing in vivo
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Physics & Mathematics (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
AU39675/93A 1992-03-25 1993-03-24 Method of intraoperatively detecting and locating tumoral tissues Abandoned AU3967593A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP92200848 1992-03-25
EP92200848 1992-03-25

Publications (1)

Publication Number Publication Date
AU3967593A true AU3967593A (en) 1993-10-21

Family

ID=8210503

Family Applications (1)

Application Number Title Priority Date Filing Date
AU39675/93A Abandoned AU3967593A (en) 1992-03-25 1993-03-24 Method of intraoperatively detecting and locating tumoral tissues

Country Status (5)

Country Link
EP (1) EP0636032A1 (de)
JP (1) JPH07505621A (de)
AU (1) AU3967593A (de)
CA (1) CA2131315A1 (de)
WO (1) WO1993018797A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2183421A1 (en) * 1994-02-18 1995-08-24 John Mertens Labelled peptide compounds
GB9417873D0 (en) * 1994-09-06 1994-10-26 Sandoz Ltd Organic compounds
AUPO066096A0 (en) * 1996-06-26 1996-07-18 Peptide Delivery Systems Pty Ltd Oral delivery of peptides
JP2001511152A (ja) * 1997-02-03 2001-08-07 マリンクロッド・インコーポレイテッド 悪性ヒト腫瘍の検出および位置特定法
WO2000018440A1 (en) * 1998-09-25 2000-04-06 Mallinckrodt Inc. Somatostatin receptor radioligand with increased uptake
US6331703B1 (en) 1999-03-12 2001-12-18 Ethicon Endo-Surgery, Inc. Guidance method for radiation detection
US6167297A (en) * 1999-05-05 2000-12-26 Benaron; David A. Detecting, localizing, and targeting internal sites in vivo using optical contrast agents
EP1633384B1 (de) 2003-05-15 2012-03-14 Trustees Of Tufts College Stabile analoga von glp-1
WO2005018682A2 (en) 2003-08-20 2005-03-03 The Regents Of The University Of California Somatostatin analogs with inhibitory activity to growth hormone release
EP2497781A1 (de) 2005-09-08 2012-09-12 Trustees Of Tufts College Stabilisierte GLP-1-Analogs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY106120A (en) * 1988-12-05 1995-03-31 Novartis Ag Peptide derivatives.
ATE120374T1 (de) * 1989-07-20 1995-04-15 Sandoz Ag Markierte polypeptidderivate.

Also Published As

Publication number Publication date
JPH07505621A (ja) 1995-06-22
CA2131315A1 (en) 1993-09-30
WO1993018797A1 (en) 1993-09-30
EP0636032A1 (de) 1995-02-01

Similar Documents

Publication Publication Date Title
EP0804252B1 (de) Monoamid, diamid, thiol enthaltende metall-chelatierende verbindungen
De Jong et al. Pre‐clinical comparison of [DTPA0] octreotide,[DTPA0, Tyr3] octreotide and [DOTA0, Tyr3] octreotide as carriers for somatostatin receptor‐targeted scintigraphy and radionuclide therapy
EP0759786B1 (de) Somatostatin bindende peptide-metallchelat konjugate
EP0614379B1 (de) Technetium - 99M markierte Peptide zur Bildformung
EP0649434B1 (de) Radioaktiv-markierte peptidderivate des somatostatin zur bildformenden und therapeutischen verwendung
EP0831938B1 (de) Mittel auf basis radiomarkierter peptide zur ortsspezifischen verabreichung
Wraight et al. The use of a chelating derivative of alpha melanocyte stimulating hormone for the clinical imaging of malignant melanoma
US20110117012A1 (en) Radiolabeled gallium complexes, methods for synthesis and use for pet imaging of egfr expression in malignant tumors
JP2001511152A (ja) 悪性ヒト腫瘍の検出および位置特定法
AU657770B2 (en) Radiolabelled somatostatin derivatives, their preparation and use
EP0719790B1 (de) Metallchelate bildende Peptide und ihre Verwendung
AU3967593A (en) Method of intraoperatively detecting and locating tumoral tissues
JP2002516883A (ja) 近接照射療法のための放射性ヨウ素化フェノール
EP0584256B1 (de) Verbindungen und pharmazeutische zusammensetzungen zum nachweis und zur lokalisierung von geweben mit neurokinin-1-rezeptoren
US11167048B2 (en) Dual targeting ligand for cancer diagnosis and treatment
US7122622B2 (en) Peptide compounds having improved binding affinity to somatostatin receptors
US6824759B2 (en) Radiolabeled vasoactive intestinal peptide analogs for imaging and therapy
EP0700930B1 (de) Peptide mit Affinität zu Tumoren und diese enthaltende radioaktive diagnostische und therapeutische Zusammensetzungen
US20040185510A1 (en) Use of labelled CCK-B receptor ligands for the detection and localization of malignant human tumours
JPH07278166A (ja) テクネチウムまたはレニウム錯体製造のためのアミノジアルキル燐酸化物をベースとする非環式キレート化剤
EP0831936A1 (de) Thiolierung von peptiden zur strahlendiagnostik und strahlentherapie auf radionuklidbasis
Maina et al. Development of 99m Tc labelled somatostatin analogues with high affinity for somatostatin receptors