AU3415395A - Antibody constructs with cdr switched variable regions - Google Patents

Antibody constructs with cdr switched variable regions

Info

Publication number
AU3415395A
AU3415395A AU34153/95A AU3415395A AU3415395A AU 3415395 A AU3415395 A AU 3415395A AU 34153/95 A AU34153/95 A AU 34153/95A AU 3415395 A AU3415395 A AU 3415395A AU 3415395 A AU3415395 A AU 3415395A
Authority
AU
Australia
Prior art keywords
cdr
variable regions
antibody constructs
switched variable
switched
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU34153/95A
Inventor
Charles R Ill
James Richard Ludwig
Radhakrishnan Rathnachalam
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eli Lilly and Co
Original Assignee
Eli Lilly and Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eli Lilly and Co filed Critical Eli Lilly and Co
Publication of AU3415395A publication Critical patent/AU3415395A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3007—Carcino-embryonic Antigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
AU34153/95A 1994-08-26 1995-08-25 Antibody constructs with cdr switched variable regions Abandoned AU3415395A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29662594A 1994-08-26 1994-08-26
US296625 1994-08-26
PCT/US1995/010791 WO1996006625A1 (en) 1994-08-26 1995-08-25 Antibody constructs with cdr switched variable regions

Publications (1)

Publication Number Publication Date
AU3415395A true AU3415395A (en) 1996-03-22

Family

ID=23142824

Family Applications (1)

Application Number Title Priority Date Filing Date
AU34153/95A Abandoned AU3415395A (en) 1994-08-26 1995-08-25 Antibody constructs with cdr switched variable regions

Country Status (2)

Country Link
AU (1) AU3415395A (en)
WO (1) WO1996006625A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPP221098A0 (en) 1998-03-06 1998-04-02 Diatech Pty Ltd V-like domain binding molecules
US7667004B2 (en) 2001-04-17 2010-02-23 Abmaxis, Inc. Humanized antibodies against vascular endothelial growth factor
US7117096B2 (en) 2001-04-17 2006-10-03 Abmaxis, Inc. Structure-based selection and affinity maturation of antibody library
CA2485732A1 (en) * 2002-05-20 2003-12-04 Abmaxis, Inc. Generation and selection of protein library in silico
CN104945505A (en) * 2010-09-29 2015-09-30 弗·哈夫曼-拉罗切有限公司 Antibody compositions and methods of use

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8607679D0 (en) * 1986-03-27 1986-04-30 Winter G P Recombinant dna product
US5013653A (en) * 1987-03-20 1991-05-07 Creative Biomolecules, Inc. Product and process for introduction of a hinge region into a fusion protein to facilitate cleavage

Also Published As

Publication number Publication date
WO1996006625A1 (en) 1996-03-07

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