AU3250093A - Nuclease stable and binding competent oligomers and methods for their use - Google Patents

Nuclease stable and binding competent oligomers and methods for their use

Info

Publication number
AU3250093A
AU3250093A AU32500/93A AU3250093A AU3250093A AU 3250093 A AU3250093 A AU 3250093A AU 32500/93 A AU32500/93 A AU 32500/93A AU 3250093 A AU3250093 A AU 3250093A AU 3250093 A AU3250093 A AU 3250093A
Authority
AU
Australia
Prior art keywords
methods
binding competent
nuclease stable
oligomers
competent oligomers
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU32500/93A
Other languages
English (en)
Inventor
Robert J Jones
Mark Matteucci
John Munger
Jeff Pudlo
Sundaramoorthi Swaminathan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gilead Sciences Inc
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of AU3250093A publication Critical patent/AU3250093A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6839—Triple helix formation or other higher order conformations in hybridisation assays

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
AU32500/93A 1991-12-12 1992-12-11 Nuclease stable and binding competent oligomers and methods for their use Abandoned AU3250093A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80671091A 1991-12-12 1991-12-12
US806710 1991-12-12

Publications (1)

Publication Number Publication Date
AU3250093A true AU3250093A (en) 1993-07-19

Family

ID=25194664

Family Applications (1)

Application Number Title Priority Date Filing Date
AU32500/93A Abandoned AU3250093A (en) 1991-12-12 1992-12-11 Nuclease stable and binding competent oligomers and methods for their use

Country Status (3)

Country Link
EP (1) EP0616612A4 (fr)
AU (1) AU3250093A (fr)
WO (1) WO1993012135A1 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU662538B2 (en) * 1991-05-21 1995-09-07 Ciba-Geigy Ag Backbone modified oligonucleotide analogs

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6251939B1 (en) 1995-06-07 2001-06-26 Promega Biosciences, Inc. Carbamate-based cationic lipids
US6274313B1 (en) 1996-03-21 2001-08-14 Pioneer-Hybrid International, Inc. Oligonucleotides with cationic phosphoramidate internucleoside linkages and methods of use
US6331617B1 (en) 1996-03-21 2001-12-18 University Of Iowa Research Foundation Positively charged oligonucleotides as regulators of gene expression
US8785409B2 (en) 2007-01-30 2014-07-22 Geron Corporation Compounds having anti-adhesive effects on cancer cells

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US327501A (en) 1885-09-29 Wet-grinding mill
US3282920A (en) * 1963-03-19 1966-11-01 Asahi Chemical Ind Method for producing 5'-nucleotides
US4458066A (en) 1980-02-29 1984-07-03 University Patents, Inc. Process for preparing polynucleotides
US4415732A (en) 1981-03-27 1983-11-15 University Patents, Inc. Phosphoramidite compounds and processes
DE3329892A1 (de) 1983-08-18 1985-03-07 Köster, Hubert, Prof. Dr., 2000 Hamburg Verfahren zur herstellung von oligonucleotiden
JP2528107B2 (ja) 1985-03-15 1996-08-28 サマ−トン，ジエ−ムス ポリヌクレオチド測定試薬と方法
US5034506A (en) 1985-03-15 1991-07-23 Anti-Gene Development Group Uncharged morpholino-based polymers having achiral intersubunit linkages
US4959463A (en) 1985-10-15 1990-09-25 Genentech, Inc. Intermediates
JPH05500799A (ja) 1989-06-05 1993-02-18 ギリアド　サイエンシス，インコーポレイテッド エキソヌクレアーゼ抵抗性オリゴヌクレオチドおよびその調製方法
US5264562A (en) 1989-10-24 1993-11-23 Gilead Sciences, Inc. Oligonucleotide analogs with novel linkages
US5495009A (en) 1989-10-24 1996-02-27 Gilead Sciences, Inc. Oligonucleotide analogs containing thioformacetal linkages
US5177198A (en) 1989-11-30 1993-01-05 University Of N.C. At Chapel Hill Process for preparing oligoribonucleoside and oligodeoxyribonucleoside boranophosphates
US5470967A (en) 1990-04-10 1995-11-28 The Dupont Merck Pharmaceutical Company Oligonucleotide analogs with sulfamate linkages
EP0531436A4 (en) 1990-05-25 1993-06-16 Gilead Sciences, Inc. Sequence-specific nonphotoactivated crosslinking agents which bind to the major groove of duplex dna
ATE154246T1 (de) 1990-07-27 1997-06-15 Isis Pharmaceuticals Inc Nuklease resistente, pyrimidin modifizierte oligonukleotide, die die gen-expression detektieren und modulieren
CA2092002A1 (fr) 1990-09-20 1992-03-21 Mark Matteucci Liaisons internucleosidiques modifiees
DK0592434T3 (da) 1990-10-26 1999-06-21 Genta Inc Forbedret fremgangsmåde til syntese af oligomerer
WO1992009705A1 (fr) 1990-11-23 1992-06-11 Gilead Sciences, Inc. Oligomeres formant un triplex et contenant des bases modifiees
AU1435492A (en) 1991-02-21 1992-09-15 Gilead Sciences, Inc. Aptamer specific for biomolecules and method of making
AU1456092A (en) 1991-02-21 1992-09-15 Gilead Sciences, Inc. Aptamers specific for thrombin and methods of use
DK51092D0 (da) 1991-05-24 1992-04-15 Ole Buchardt Oligonucleotid-analoge betegnet pna, monomere synthoner og fremgangsmaade til fremstilling deraf samt anvendelser deraf
WO1993009127A1 (fr) 1991-11-07 1993-05-13 Gilead Sciences, Inc. Formation amelioree d'une triple helice, grace a des oligonucleotides contenant la 2'-desoxy-7-desazaxanthosine, la 2'-desoxy-7-desazaguanosine et des composes analogues
WO1993024507A1 (fr) 1992-05-28 1993-12-09 Gilead Sciences, Inc. Oligomeres a conformation restreinte contenant des liaisons amide ou carbamate pour effectuer une liaison specifique d'une sequence
US5817781A (en) 1992-06-01 1998-10-06 Gilead Sciences, Inc. Modified internucleoside linkages (II)
TWI515034B (zh) 2013-09-16 2016-01-01 cheng wei Liu Magic blocks of dynamic fault-tolerant structures
US10368098B2 (en) 2014-06-20 2019-07-30 Samsung Electronics Co., Ltd. Method and device for transmitting prediction mode of depth image for interlayer video encoding and decoding
US10881198B1 (en) 2020-03-09 2021-01-05 You Yun Ren Jia (Shenzhen) Service Co., Ltd. Sink shelf organizer

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU662538B2 (en) * 1991-05-21 1995-09-07 Ciba-Geigy Ag Backbone modified oligonucleotide analogs
AU666121B2 (en) * 1991-05-21 1996-02-01 Isis Pharmaceuticals, Inc. Backbone modified oligonucleotide analogues

Also Published As

Publication number Publication date
EP0616612A4 (fr) 1995-01-11
EP0616612A1 (fr) 1994-09-28
WO1993012135A1 (fr) 1993-06-24

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