AU3211699A - Orphan nuclear receptor - Google Patents

Orphan nuclear receptor

Info

Publication number
AU3211699A
AU3211699A AU32116/99A AU3211699A AU3211699A AU 3211699 A AU3211699 A AU 3211699A AU 32116/99 A AU32116/99 A AU 32116/99A AU 3211699 A AU3211699 A AU 3211699A AU 3211699 A AU3211699 A AU 3211699A
Authority
AU
Australia
Prior art keywords
nuclear receptor
orphan nuclear
orphan
receptor
nuclear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU32116/99A
Inventor
Steven Anthony Kliewer
Timothy Mark Willson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of AU3211699A publication Critical patent/AU3211699A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6897—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids involving reporter genes operably linked to promoters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70567—Nuclear receptors, e.g. retinoic acid receptor [RAR], RXR, nuclear orphan receptors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
AU32116/99A 1998-03-27 1999-03-26 Orphan nuclear receptor Abandoned AU3211699A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US7959398P 1998-03-27 1998-03-27
US60079593 1998-03-27
PCT/US1999/006737 WO1999048915A1 (en) 1998-03-27 1999-03-26 Orphan nuclear receptor

Publications (1)

Publication Number Publication Date
AU3211699A true AU3211699A (en) 1999-10-18

Family

ID=22151520

Family Applications (1)

Application Number Title Priority Date Filing Date
AU32116/99A Abandoned AU3211699A (en) 1998-03-27 1999-03-26 Orphan nuclear receptor

Country Status (4)

Country Link
EP (1) EP1066320A4 (en)
JP (1) JP2002535241A (en)
AU (1) AU3211699A (en)
WO (1) WO1999048915A1 (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6756491B2 (en) 1998-01-09 2004-06-29 The Salk Institute For Biological Studies Steroid-activated nuclear receptors and uses therefor
US6984773B1 (en) * 1998-01-09 2006-01-10 The Salk Institute For Biological Studies Transgenic mice expressing a human SXR receptor polypeptide
AUPP135698A0 (en) 1998-01-15 1998-02-05 Commonwealth Scientific And Industrial Research Organisation Insectical modalities
US7238491B1 (en) 1998-03-27 2007-07-03 Smithkline Beecham Corporation Pregnane X receptor method
AUPP362898A0 (en) 1998-05-21 1998-06-11 University Of Sydney, The Xenobiotic induction of gene expression
CA2377804A1 (en) * 1999-07-01 2001-01-11 Commonwealth Scientific And Industrial Research Organisation Novel genetic sequences encoding steroid and juvenile hormone receptor polypeptides and uses therefor
EP1088900A1 (en) 1999-09-10 2001-04-04 Epidauros Biotechnologie AG Polymorphisms in the human CYP3A4, CYP3A7 and hPXR genes and their use in diagnostic and therapeutic applications
AU2006200258B2 (en) * 1999-12-09 2009-04-09 The Salk Institute For Biological Studies Novel steroid-activated nuclear receptors and uses therefor
AU2001233051A1 (en) * 2000-01-28 2001-08-07 Incyte Genomics, Inc. Nuclear hormone receptors
CA2405440A1 (en) * 2000-04-12 2001-10-25 Puracyp Compositions and methods for induction of proteins involved in xenobiotic metabolism
AU2001284343A1 (en) * 2000-06-21 2002-01-02 Glaxo Group Limited An orphan nuclear receptor
WO2002008451A2 (en) * 2000-07-25 2002-01-31 Epidauros Biotechnologie Ag Assay for screening compounds for inducing drug metabolizing enzymes
WO2002018420A2 (en) * 2000-08-28 2002-03-07 Lion Bioscience Ag Cofactors of the pregnane x receptor and methods of use
AU2002213660A1 (en) * 2000-11-01 2002-05-15 The University Of Sydney Transgenic animals for analysing CYP3A4 cytochrome P450 gene regulation
AUPR116100A0 (en) 2000-11-01 2000-11-23 University Of Sydney, The P450 gene regulation
EP1392725A1 (en) * 2001-05-24 2004-03-03 SmithKline Beecham Corporation Nonhuman pregnane x receptor sequences for use in comparative pharmacology
EP3209671B8 (en) 2014-10-21 2019-07-31 Council of Scientific and Industrial Research Alkylidene phosphonate esters as p-glycoprotein inducers

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9801148D0 (en) * 1997-10-14 1998-03-31 Pharmacia & Upjohn Ab New receptors
EP1044216A4 (en) * 1997-12-12 2001-10-31 Merck & Co Inc DNA MOLECULES ENCODING HUMAN NUCLEAR RECEPTOR PROTEINS, nNR7 AND nNR7-1
US6756491B2 (en) * 1998-01-09 2004-06-29 The Salk Institute For Biological Studies Steroid-activated nuclear receptors and uses therefor

Also Published As

Publication number Publication date
EP1066320A4 (en) 2005-03-16
WO1999048915A1 (en) 1999-09-30
JP2002535241A (en) 2002-10-22
WO1999048915A9 (en) 1999-11-18
EP1066320A1 (en) 2001-01-10

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase