AU3125695A - Neurologically active aminosteroids - Google Patents

Neurologically active aminosteroids

Info

Publication number
AU3125695A
AU3125695A AU31256/95A AU3125695A AU3125695A AU 3125695 A AU3125695 A AU 3125695A AU 31256/95 A AU31256/95 A AU 31256/95A AU 3125695 A AU3125695 A AU 3125695A AU 3125695 A AU3125695 A AU 3125695A
Authority
AU
Australia
Prior art keywords
aminosteroids
neurologically active
neurologically
active
active aminosteroids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU31256/95A
Inventor
Gordon L. Bundy
Eric Jon Jacobsen
Michael A Wynalda
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pharmacia and Upjohn Co
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of AU3125695A publication Critical patent/AU3125695A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0007—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa
    • C07J5/0023—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16
    • C07J5/003—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group including 16-alkylidene substitutes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16—Anti-Parkinson drugs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Psychology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU31256/95A 1994-07-21 1995-07-18 Neurologically active aminosteroids Abandoned AU3125695A (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US27863394A 1994-07-21 1994-07-21
US36181894A 1994-12-22 1994-12-22
US361818 1994-12-22
US47387395A 1995-06-07 1995-06-07
PCT/US1995/008646 WO1996003421A1 (en) 1994-07-21 1995-07-18 Neurologically active aminosteroids
US278633 2002-10-22
US473873 2006-06-23

Publications (1)

Publication Number Publication Date
AU3125695A true AU3125695A (en) 1996-02-22

Family

ID=27403009

Family Applications (1)

Application Number Title Priority Date Filing Date
AU31256/95A Abandoned AU3125695A (en) 1994-07-21 1995-07-18 Neurologically active aminosteroids

Country Status (3)

Country Link
JP (1) JP2002500616A (en)
AU (1) AU3125695A (en)
WO (1) WO1996003421A1 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10505063A (en) * 1994-09-01 1998-05-19 ファルマシア・アンド・アップジョン・カンパニー Parenteral co-solvent formulation of tirilazad
CA2852057C (en) 2011-10-14 2022-06-07 Sage Therapeutics, Inc. 3,3-disubstituted 19-nor pregnane compounds, compositions, and uses thereof for the treatment of cns related disorders
BR112014018110B1 (en) 2012-01-23 2022-06-07 Sage Therapeutics, Inc Aqueous pharmaceutical compositions formulated for parenteral administration and use of allopregnanolone and sulfbutylether-b-cyclodextrin
LT2986624T (en) 2013-04-17 2020-07-10 Sage Therapeutics, Inc. 19-nor neuroactive steroids for methods of treatment
US9725481B2 (en) 2013-04-17 2017-08-08 Sage Therapeutics, Inc. 19-nor C3, 3-disubstituted C21-C-bound heteroaryl steroids and methods of use thereof
SG10201802389SA (en) 2013-04-17 2018-04-27 Sage Therapeutics Inc 19-nor c3,3-disubstituted c21-n-pyrazolyl steroids and methods of use thereof
US20160068563A1 (en) 2013-04-17 2016-03-10 Boyd L. Harrison 19-nor neuroactive steroids and methods of use thereof
AU2014290400B2 (en) 2013-07-19 2019-12-05 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
PT3035940T (en) 2013-08-23 2019-01-28 Sage Therapeutics Inc Neuroactive steroids, compositions, and uses thereof
US10246482B2 (en) 2014-06-18 2019-04-02 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
KR102612943B1 (en) 2014-10-16 2023-12-13 세이지 테라퓨틱스, 인크. Compositions and methods for treating cns disorders
EP3753927B1 (en) 2014-10-16 2023-07-19 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
PT3224269T (en) 2014-11-27 2020-06-01 Sage Therapeutics Inc Compositions and methods for treating cns disorders
SI3250210T1 (en) 2015-01-26 2021-07-30 Sage Therapeutics, Inc. Compositions and methods for treating cns disorders
US10329320B2 (en) 2015-02-20 2019-06-25 Sage Therapeutics, Inc. Neuroactive steroids, compositions, and uses thereof
CN109414444A (en) 2016-03-08 2019-03-01 萨奇治疗股份有限公司 Neuroactive steroids, its composition and purposes
US20190233465A1 (en) 2016-07-11 2019-08-01 Sage Therapeutics, Inc. C7, c12, and c16 substituted neuroactive steroids and their methods of use
EP4302764A2 (en) 2016-07-11 2024-01-10 Sage Therapeutics, Inc. C17, c20, and c21 substituted neuroactive steroids and their methods of use
MX2021014515A (en) 2019-05-31 2022-03-22 Sage Therapeutics Inc Neuroactive steroids and compositions thereof.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1987001706A2 (en) * 1985-09-12 1987-03-26 The Upjohn Company C20 through c26 amino steroids
JP2832632B2 (en) * 1990-05-18 1998-12-09 本田技研工業株式会社 Transmission in motorcycle

Also Published As

Publication number Publication date
JP2002500616A (en) 2002-01-08
WO1996003421A1 (en) 1996-02-08

Similar Documents

Publication Publication Date Title
AU1385195A (en) Pesticides
AU3304795A (en) Bisresorcinyltriazines
AU2832295A (en) Cytoanalyzer
AU3304995A (en) 2-Hydroxyphenyltriazines
EP0688698A3 (en) Vehicle network
AU3125695A (en) Neurologically active aminosteroids
AU2837895A (en) Thiazine- or thiazepine-derivatives
AU4131596A (en) Polyglycomers
AU4044795A (en) Handleset
AU2308295A (en) Heterocyclylbenzonitriles
AU3554995A (en) Antipicornaviral agents
AU1963395A (en) Boom-structure
AU4029295A (en) Thienopyridones
AU7469594A (en) Poop-scoop
AU3166195A (en) Acylimidazopyridines
AU1716895A (en) Vs ribozymes
AU4590996A (en) Boekomslag
AU1093697A (en) Active bio-compounds
AU3166095A (en) Benzylimidazopyridines
AU1603595A (en) Meso-azanoradamantanes
AU2411395A (en) Hydrocopter
AU3446995A (en) Biodestumping
AU4783896A (en) Active bio-compounds
AU3417395A (en) Hydro-ethano-indeno-pyridines
AU653704B3 (en) Aperture former