AU3118989A - Benzocycloheptene derivatives - Google Patents

Benzocycloheptene derivatives

Info

Publication number
AU3118989A
AU3118989A AU31189/89A AU3118989A AU3118989A AU 3118989 A AU3118989 A AU 3118989A AU 31189/89 A AU31189/89 A AU 31189/89A AU 3118989 A AU3118989 A AU 3118989A AU 3118989 A AU3118989 A AU 3118989A
Authority
AU
Australia
Prior art keywords
benzocycloheptene derivatives
benzocycloheptene
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU31189/89A
Other versions
AU612471B2 (en
Inventor
Andreas Bomhard
Jurgen Dammgen
Joachim Heiden
Walter Kobinger
Christian Lillie
Manfred Psiorz
Manfred Reiffen
Volker Trach
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH and Co KG
Original Assignee
Dr Karl Thomae GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dr Karl Thomae GmbH filed Critical Dr Karl Thomae GmbH
Publication of AU3118989A publication Critical patent/AU3118989A/en
Application granted granted Critical
Publication of AU612471B2 publication Critical patent/AU612471B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • C07C255/49Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
    • C07C255/58Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and singly-bound nitrogen atoms, not being further bound to other hetero atoms, bound to the carbon skeleton
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/56Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
    • C07C217/60Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms linked by carbon chains having two carbon atoms between the amino groups and the six-membered aromatic ring or the condensed ring system containing that ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/54Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C217/74Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with rings other than six-membered aromatic rings being part of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/78Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • C07C217/80Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings
    • C07C217/82Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring
    • C07C217/84Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton having amino groups and etherified hydroxy groups bound to carbon atoms of non-condensed six-membered aromatic rings of the same non-condensed six-membered aromatic ring the oxygen atom of at least one of the etherified hydroxy groups being further bound to an acyclic carbon atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63Esters of sulfonic acids
    • C07C309/64Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • C07C309/66Methanesulfonates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/12One of the condensed rings being a six-membered aromatic ring the other ring being at least seven-membered

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
AU31189/89A 1988-03-10 1989-03-10 Benzocycloheptene derivatives Ceased AU612471B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3807813A DE3807813A1 (en) 1988-03-10 1988-03-10 NEW BENZOCYCLOHEPEN DERIVATIVES, MEDICAMENTS CONTAINING SUCH COMPOUNDS AND METHOD FOR THE PRODUCTION THEREOF
DE3807813 1988-03-10

Publications (2)

Publication Number Publication Date
AU3118989A true AU3118989A (en) 1989-09-14
AU612471B2 AU612471B2 (en) 1991-07-11

Family

ID=6349282

Family Applications (1)

Application Number Title Priority Date Filing Date
AU31189/89A Ceased AU612471B2 (en) 1988-03-10 1989-03-10 Benzocycloheptene derivatives

Country Status (14)

Country Link
EP (1) EP0332064A3 (en)
JP (1) JPH024739A (en)
KR (1) KR890014446A (en)
AU (1) AU612471B2 (en)
DD (1) DD279238A5 (en)
DE (1) DE3807813A1 (en)
DK (1) DK114189A (en)
FI (1) FI891115A (en)
HU (1) HUT54616A (en)
IL (1) IL89533A0 (en)
NO (1) NO891009L (en)
NZ (1) NZ228277A (en)
PH (1) PH26473A (en)
ZA (1) ZA891797B (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6310107B1 (en) 1997-02-27 2001-10-30 Takeda Chemical Industries, Ltd. Amine compounds, their production and use as amyloid-β production inhibitors
US6784314B2 (en) 2000-04-03 2004-08-31 Takeda Chemical Industries, Ltd. Process for producing amine derivatives

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE467076B (en) * 1989-06-16 1992-05-18 Gunnar Martin Natanael Staalma SET AND DEVICE FOR THEORETARY PROOF
SE9103745D0 (en) * 1991-12-18 1991-12-18 Wikstroem Haakan ARYL-TRIFLATES AND RELATED COMPOUNDS
CA2259927A1 (en) 1996-07-12 1998-01-22 Leukosite, Inc. Chemokine receptor antagonists and methods of use therefor
AR035431A1 (en) 2001-02-13 2004-05-26 Aventis Pharma Gmbh 6,7,8,9-TETRAHIDRO-5H-BENZOCICLOHEPTENIL ACILATED AMINES, A METHOD FOR SYNTHESIS, PHARMACEUTICAL COMPOSITIONS AND THE USE OF SUCH COMPOUNDS FOR THE MANUFACTURE OF MEDICINES
ZA200706586B (en) * 2003-08-29 2008-07-30 Mitsui Chemicals Inc Insecticide for agricultural or horticultural use and method of use thereof
PL2354134T3 (en) * 2008-12-05 2016-07-29 Astellas Pharma Inc 2h-chromene derivatives as stimulators of sphingosine 1-phosphate receptor
JP6088595B2 (en) 2015-07-24 2017-03-01 ファナック株式会社 Machine tool, partition device, and robot system including partition member that shields part of opening of cover

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ213651A (en) * 1984-10-11 1989-07-27 Hoffmann La Roche Tetrahydronapthalene derivatives and medicaments

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6310107B1 (en) 1997-02-27 2001-10-30 Takeda Chemical Industries, Ltd. Amine compounds, their production and use as amyloid-β production inhibitors
US6613805B2 (en) 1997-02-27 2003-09-02 Takeda Chemical Industries, Ltd. Amine compounds, their production and use
US7256204B2 (en) 1997-02-27 2007-08-14 Takeda Pharmaceutical Company Limited Amine compounds, their production and use
US6784314B2 (en) 2000-04-03 2004-08-31 Takeda Chemical Industries, Ltd. Process for producing amine derivatives

Also Published As

Publication number Publication date
FI891115A0 (en) 1989-03-09
KR890014446A (en) 1989-10-23
DK114189A (en) 1989-09-11
JPH024739A (en) 1990-01-09
IL89533A0 (en) 1989-09-10
PH26473A (en) 1992-07-23
DD279238A5 (en) 1990-05-30
EP0332064A3 (en) 1990-12-05
FI891115A (en) 1989-09-11
DE3807813A1 (en) 1989-09-21
NO891009D0 (en) 1989-03-09
EP0332064A2 (en) 1989-09-13
HUT54616A (en) 1991-03-28
DK114189D0 (en) 1989-03-09
AU612471B2 (en) 1991-07-11
NO891009L (en) 1989-09-11
ZA891797B (en) 1990-11-28
NZ228277A (en) 1991-06-25

Similar Documents

Publication Publication Date Title
AU3715993A (en) N-isopropylheteroaryloxyacetanilides
AU2864489A (en) 16-dehydro-vitamin d3-derivatives
AU3301689A (en) 1-azabicyclo-alkyl derivatives
AU3642589A (en) 1-aryl-2-naphthoylamines
AU3163389A (en) 5-amino-1-phenylpyrazoles
AU2963389A (en) Pyranobenzoxadiazole derivatives
AU616039B2 (en) Benzopyranol derivatives
AU3234289A (en) Co-dispenser
AU3334389A (en) Rutheniumcomplex-compounds
AU3315889A (en) Phosphonoalkylpurine derivatives
AU3118989A (en) Benzocycloheptene derivatives
AU4628489A (en) Assayomate
AU4601389A (en) Novel benzopyranylpyrrolinone derivatives
AU3330789A (en) Arylpropanamine derivatives
AU3300089A (en) Triazoloazines
AU3301589A (en) Oxadiazole-1-azabicyclo-alkane derivatives
AU3156989A (en) Androst-4-ene derivatives
AU3869789A (en) Pyrazolo-pyrrolo-pyrimidine-diones
AU3315089A (en) 2-substituted-2-cyclopentenones
AU3508989A (en) Des-17-histidine-calcitonin
AU4679689A (en) Polyhydroxybenzylpxypropanolamines
AU4463989A (en) Pyranylethyl-naphthalene derivatives
AU2508688A (en) Yacht-hull
AU3851189A (en) Recombinomas
AU3672689A (en) Substituted azacyclohexyl derivatives