AU2869092A - Heterocyclic 3-phenylpyrrolidin-2-ones, their preparation and use for the manufacture of a medicament for inhibiting tumor necrosis factor production - Google Patents
Heterocyclic 3-phenylpyrrolidin-2-ones, their preparation and use for the manufacture of a medicament for inhibiting tumor necrosis factor productionInfo
- Publication number
- AU2869092A AU2869092A AU28690/92A AU2869092A AU2869092A AU 2869092 A AU2869092 A AU 2869092A AU 28690/92 A AU28690/92 A AU 28690/92A AU 2869092 A AU2869092 A AU 2869092A AU 2869092 A AU2869092 A AU 2869092A
- Authority
- AU
- Australia
- Prior art keywords
- phenylpyrrolidin
- heterocyclic
- medicament
- ones
- manufacture
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US916733 | 1978-06-19 | ||
US77650891A | 1991-10-11 | 1991-10-11 | |
US776508 | 1991-10-11 | ||
US91673392A | 1992-07-20 | 1992-07-20 |
Publications (1)
Publication Number | Publication Date |
---|---|
AU2869092A true AU2869092A (en) | 1993-05-03 |
Family
ID=27119195
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU28690/92A Abandoned AU2869092A (en) | 1991-10-11 | 1992-10-02 | Heterocyclic 3-phenylpyrrolidin-2-ones, their preparation and use for the manufacture of a medicament for inhibiting tumor necrosis factor production |
Country Status (4)
Country | Link |
---|---|
AU (1) | AU2869092A (en) |
MX (1) | MX9205875A (en) |
PT (1) | PT100947A (en) |
WO (1) | WO1993007141A1 (en) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5665754A (en) * | 1993-09-20 | 1997-09-09 | Glaxo Wellcome Inc. | Substituted pyrrolidines |
ES2139754T3 (en) * | 1993-11-26 | 2000-02-16 | Pfizer | 3-PHENYL-2-ISOXAZOLINES AS ANTI-INFLAMMATORY AGENTS. |
US5612353A (en) * | 1995-06-07 | 1997-03-18 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | Substituted (sulfinic acid, sulfonic acid, sulfonylamino or sulfinylamino) N-[(aminoiminomethyl)phenylalkyl]-azaheterocyclylamide compounds |
ATE360419T1 (en) * | 1995-09-19 | 2007-05-15 | Solomon B Margolin | USE OF N-SUBSTITUTED PYRIDONES AS TUMOR NECROSIS FACTOR ALPHA INHIBITORS |
DE19751062A1 (en) * | 1997-11-18 | 1999-07-08 | Univ Ludwigs Albert | 4-substituted 2-pyrrolidinone derivatives to reduce extracellular glutamate levels |
EP1004578B1 (en) * | 1998-11-05 | 2004-02-25 | Pfizer Products Inc. | 5-oxo-pyrrolidine-2-carboxylic acid hydroxamide derivatives |
CA2402384A1 (en) | 2000-03-16 | 2001-09-20 | Inflazyme Pharmaceuticals Ltd. | Benzylated pde4 inhibitors |
US7056917B2 (en) | 2001-04-26 | 2006-06-06 | Daiichi Pharmaceutical Co., Ltd. | Drug efflux pump inhibitor |
ATE444065T1 (en) * | 2001-10-16 | 2009-10-15 | Memory Pharm Corp | 4(4-ALKOXY-3-HYDROXYPHENYL)-2-PYRROLIDONE DERIVATIVES AS PDE-4 INHIBITORS FOR THE TREATMENT OF NEUROLOGICAL SYNDROMES |
DE10222024A1 (en) * | 2002-05-17 | 2003-11-27 | Bayer Ag | New N-substituted N'-((5-oxo-2-pyrrolidinyl)-phenyl)-(thio)ureas, are antiviral agents especially effective against human cytomegalovirus |
US7495016B2 (en) | 2002-10-21 | 2009-02-24 | Irm Llc | Pyrrolidones with anti-HIV activity |
DE60326752D1 (en) | 2002-11-26 | 2009-04-30 | Pfizer Prod Inc | PHENYL SUBTITUED PIPERIDINE COMPOUNDS FOR USE AS PPAR ACTIVATORS |
DE10257786A1 (en) * | 2002-12-11 | 2004-07-01 | Bayer Healthcare Ag | oxazolidinones |
KR20060039392A (en) * | 2003-04-16 | 2006-05-08 | 메모리 파마슈티칼스 코포레이션 | Phosphodiesterase 4 inhibitors |
EP1631568A1 (en) | 2003-04-18 | 2006-03-08 | Memory Pharmaceuticals Corporation | Pyrazole derivatives as phosphodiesterase 4 inhibitors |
DE602004019814D1 (en) * | 2003-12-02 | 2009-04-16 | Ucb Pharma Sa | IMIDAZOLE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND THEIR APPLICATIONS |
AU2005295753A1 (en) | 2004-10-15 | 2006-04-27 | Memory Pharmaceuticals Corporation | Pyrazole derivatives as phosphodiesterase 4 inhibitors |
CN101166737A (en) | 2004-10-20 | 2008-04-23 | 记忆药物公司 | Phosphodiesterase 4 inhibitors |
CA2610042C (en) * | 2005-06-01 | 2013-04-23 | Ucb Pharma, S.A. | 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1350582A (en) * | 1970-07-24 | 1974-04-18 | Ucb Sa | Cerivatives of 2-pyrrolidinone |
JPS5182258A (en) * | 1974-04-25 | 1976-07-19 | Yoshitomi Pharmaceutical | PIRORIJINON JUDOTAINO SEIZOHO |
US4476311A (en) * | 1980-03-12 | 1984-10-09 | The Purdue Frederick Company | Analgesic 4-carboxy-pyrrolidin-2-one compound |
EP0114033B1 (en) * | 1982-12-21 | 1988-10-12 | Ciba-Geigy Ag | Substituted azabicycloalkanes, their use, pharmaceutical preparations containing these compounds and process for preparing these compounds |
FI875101A (en) * | 1986-12-03 | 1988-06-04 | Tanabe Seiyaku Co | LAKTAMDERIVAT OCH PREPARAT INNEHAOLLANDE DESSA. |
DE3823299A1 (en) * | 1988-07-07 | 1990-01-11 | Schering Ag | SUBSTITUTED PHENYL-PYRROLIDIN-2-ONE, -OXAZOLIDIN-2-ONE AND -IMIDAZOLIDIN-2-ONE, THEIR PRODUCTION AND USE IN MEDICINAL PRODUCTS |
DD299058A5 (en) * | 1990-01-31 | 1992-03-26 | Arzneimittelwerk Dresden Gmbh,De | PROCESS FOR THE PREPARATION OF N-ACYL-4-PHENYL-PYRROLIDIN-2-ONES WITH CEREBROPROTECTIVE EFFECT |
-
1992
- 1992-10-02 WO PCT/US1992/008611 patent/WO1993007141A1/en active Application Filing
- 1992-10-02 AU AU28690/92A patent/AU2869092A/en not_active Abandoned
- 1992-10-09 PT PT10094792A patent/PT100947A/en not_active Application Discontinuation
- 1992-10-13 MX MX9205875A patent/MX9205875A/en unknown
Also Published As
Publication number | Publication date |
---|---|
PT100947A (en) | 1994-02-28 |
WO1993007141A1 (en) | 1993-04-15 |
MX9205875A (en) | 1993-07-01 |
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