AU2017262960A1 - Substituted 5,6,7,8-tetrahydro(1,2,4)triazolo(4,3-a)pyridine-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo(2,1-c)(1,2,4)triazol-3-ones, and use thereof - Google Patents

Substituted 5,6,7,8-tetrahydro(1,2,4)triazolo(4,3-a)pyridine-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo(2,1-c)(1,2,4)triazol-3-ones, and use thereof

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Publication number
AU2017262960A1
AU2017262960A1 AU2017262960A AU2017262960A AU2017262960A1 AU 2017262960 A1 AU2017262960 A1 AU 2017262960A1 AU 2017262960 A AU2017262960 A AU 2017262960A AU 2017262960 A AU2017262960 A AU 2017262960A AU 2017262960 A1 AU2017262960 A1 AU 2017262960A1
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AU
Australia
Prior art keywords
tetrahydro
ones
triazolo
pyrrolo
triazol
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Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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AU2017262960A
Other versions
AU2017262960B2 (en
Inventor
Volker BADOCK
Nicole BIBER
Damian Brockschnieder
Kersten Matthias Gericke
Florian KÖLLING
Niels Lindner
Klemens Lustig
Jörg MEDING
Heinrich Meier
Hideki MIYATAKE ONDOZABAL
Steven Moore
Dieter Moosmayer
Thomas Neubauer
Alexander Schulz
Martina SCHÄFER
Carsten TERJUNG
Andreas Timmermann
Dmitry Zubov
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Bayer Pharma AG
Original Assignee
Bayer AG
Bayer Pharma AG
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Publication date
Application filed by Bayer AG, Bayer Pharma AG filed Critical Bayer AG
Priority claimed from PCT/EP2017/060900 external-priority patent/WO2017194459A1/en
Publication of AU2017262960A1 publication Critical patent/AU2017262960A1/en
Application granted granted Critical
Publication of AU2017262960B2 publication Critical patent/AU2017262960B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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AU2017262960A 2016-05-09 2017-05-08 Substituted 5,6,7,8-tetrahydro(1,2,4)triazolo(4,3-a)pyridine-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo(2,1-c)(1,2,4)triazol-3-ones, and use thereof Active AU2017262960B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP16168809 2016-05-09
EPEP16168809.8 2016-05-09
PCT/EP2017/060900 WO2017194459A1 (en) 2016-05-09 2017-05-08 Substituted 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridine-3(2h)-ones and 2,5,6,7-tetrahydro-3h-pyrrolo[2,1-c][1,2,4]triazol-3-ones, and use thereof

Publications (2)

Publication Number Publication Date
AU2017262960A1 true AU2017262960A1 (en) 2018-11-15
AU2017262960B2 AU2017262960B2 (en) 2021-11-11

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AU2017262960A Active AU2017262960B2 (en) 2016-05-09 2017-05-08 Substituted 5,6,7,8-tetrahydro(1,2,4)triazolo(4,3-a)pyridine-3(2H)-ones and 2,5,6,7-tetrahydro-3H-pyrrolo(2,1-c)(1,2,4)triazol-3-ones, and use thereof

Country Status (30)

Country Link
US (1) US10722501B2 (en)
JP (1) JP6987784B2 (en)
KR (1) KR102438965B1 (en)
CN (1) CN109476658B (en)
AR (1) AR110600A1 (en)
AU (1) AU2017262960B2 (en)
BR (1) BR112018073061A2 (en)
CA (1) CA3023383A1 (en)
CL (1) CL2018003194A1 (en)
CO (1) CO2018012136A2 (en)
CR (1) CR20180540A (en)
CU (1) CU24536B1 (en)
DO (1) DOP2018000246A (en)
EA (1) EA037531B1 (en)
EC (1) ECSP18083950A (en)
GE (1) GEP20227365B (en)
IL (1) IL262548B (en)
JO (1) JOP20170113B1 (en)
MX (1) MX2018013797A (en)
NI (1) NI201800118A (en)
PE (1) PE20190325A1 (en)
PH (1) PH12018502359A1 (en)
SA (1) SA518400397B1 (en)
SG (1) SG11201809724PA (en)
SV (1) SV2018005783A (en)
TN (1) TN2018000376A1 (en)
TW (1) TWI758291B (en)
UA (1) UA125644C2 (en)
UY (1) UY37234A (en)
WO (1) WO2017194459A1 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MX2007009796A (en) 2007-08-14 2009-02-25 Cell Therapy And Technology S Gel containing pirfenidone.
MX346763B (en) 2012-03-28 2017-03-31 Cell Therapy And Tech S A De C V Semi-solid topical composition which contains pirfenidone and modified diallyl disulphide oxide (m-ddo) for eliminating or preventing acne.
US11337973B2 (en) 2017-11-07 2022-05-24 Bayer Aktiengesellschaft Substituted [1,2,4]triazolo[4,3-A]pyrazines as prolyl endopeptidase inhibitors
CN110950797A (en) * 2019-12-06 2020-04-03 丽水绿氟科技有限公司 Preparation method of 2-trifluoromethyl-3-fluoro-4-picolinic acid and derivatives thereof
CN115466212B (en) * 2022-10-26 2023-09-22 河南农业大学 2-trifluoromethyl quinoline compound and synthetic method and application thereof

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US3966781A (en) 1970-12-17 1976-06-29 Merck Sharp & Dohme (I.A.) Corporation Deuteration of functional group-containing hydrocarbons
HUT76640A (en) * 1995-08-17 1997-10-28 Chinoin Gyogyszer Es Vegyeszet Compounds of pharmaceutical activity cyclic amide derivatives, pharmaceutical compositions containing them, process for producing them and their use
DE19834044A1 (en) 1998-07-29 2000-02-03 Bayer Ag New substituted pyrazole derivatives
DE19834047A1 (en) 1998-07-29 2000-02-03 Bayer Ag Substituted pyrazole derivatives
DE19943639A1 (en) 1999-09-13 2001-03-15 Bayer Ag Dicarboxylic acid derivatives with novel pharmaceutical properties
DE19943634A1 (en) 1999-09-13 2001-04-12 Bayer Ag Novel dicarboxylic acid derivatives with pharmaceutical properties
DE19943636A1 (en) 1999-09-13 2001-03-15 Bayer Ag Novel dicarboxylic acid derivatives with pharmaceutical properties
DE19943635A1 (en) 1999-09-13 2001-03-15 Bayer Ag Novel aminodicarboxylic acid derivatives with pharmaceutical properties
AR031176A1 (en) 2000-11-22 2003-09-10 Bayer Ag NEW DERIVATIVES OF PIRAZOLPIRIDINA SUBSTITUTED WITH PIRIDINE
DE10110750A1 (en) 2001-03-07 2002-09-12 Bayer Ag Novel aminodicarboxylic acid derivatives with pharmaceutical properties
DE10110749A1 (en) 2001-03-07 2002-09-12 Bayer Ag Substituted aminodicarboxylic acid derivatives
DE10220570A1 (en) 2002-05-08 2003-11-20 Bayer Ag Carbamate-substituted pyrazolopyridines
US7618983B2 (en) 2004-11-10 2009-11-17 Janssen Pharmaceutica, N.V. Bicyclic triazole α4 integrin inhibitors
US8524654B2 (en) * 2007-05-21 2013-09-03 The Uab Research Foundation Prolyl endopeptidase inhibitors for reducing or preventing neutrophilic inflammation
WO2011062864A2 (en) 2009-11-17 2011-05-26 Emory University Inhibitors of nox enzymes and methods of use thereof
DE102010021637A1 (en) 2010-05-26 2011-12-01 Bayer Schering Pharma Aktiengesellschaft Substituted 5-fluoro-1H-pyrazolopyridines and their use
EP2708539A1 (en) 2010-07-09 2014-03-19 Bayer Intellectual Property GmbH Annulated pyrimidines and triazines and their use
DE102010040233A1 (en) 2010-09-03 2012-03-08 Bayer Schering Pharma Aktiengesellschaft Bicyclic aza heterocycles and their use
DE102010043379A1 (en) 2010-11-04 2012-05-10 Bayer Schering Pharma Aktiengesellschaft Substituted 6-fluoro-1H-pyrazolo [4,3-b] pyridines and their use
EP2675440B1 (en) 2011-02-14 2020-03-25 Merck Sharp & Dohme Corp. Cathepsin cysteine protease inhibitors
KR20130091464A (en) * 2012-02-08 2013-08-19 한미약품 주식회사 Triazolopyridine derivatives as a tyrosine kinase inhibitor
US9624214B2 (en) 2012-11-05 2017-04-18 Bayer Pharma Aktiengesellschaft Amino-substituted imidazo[1,2-a]pyridinecarboxamides and their use

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