AU2014243418B2 - Modified binding proteins inhibiting the VEGF-A receptor interaction - Google Patents
Modified binding proteins inhibiting the VEGF-A receptor interactionInfo
- Publication number
- AU2014243418B2 AU2014243418B2 AU2014243418A AU2014243418A AU2014243418B2 AU 2014243418 B2 AU2014243418 B2 AU 2014243418B2 AU 2014243418 A AU2014243418 A AU 2014243418A AU 2014243418 A AU2014243418 A AU 2014243418A AU 2014243418 B2 AU2014243418 B2 AU 2014243418B2
- Authority
- AU
- Australia
- Prior art keywords
- binding proteins
- vegf
- binding
- receptor interaction
- proteins
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Abstract
MODIFIED BINDING PROTEINS INHIBITING THE VEGF-A RECEPTOR INTERACTION The present invention relates to binding proteins specific for VEGF-A, in particular to recombinant binding proteins comprising a polyethylene glycol moiety and a binding domain, which inhibits VEGF-Axxx binding to VEGFR-2. Examples of such recombinant binding proteins are proteins which comprise an ankyrin repeat domain with the desired binding specificity, and a polyethylene glycol moiety. The binding proteins are useful in the treatment of cancer and other pathological conditions, e.g. eye diseases such as age-related macular degeneration.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2014243418A AU2014243418B2 (en) | 2010-04-30 | 2014-10-09 | Modified binding proteins inhibiting the VEGF-A receptor interaction |
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP10161685.2 | 2010-04-30 | ||
AU2011247563A AU2011247563B2 (en) | 2010-04-30 | 2011-04-29 | Modified binding proteins inhibiting the VEGF-A receptor interaction |
AU2014243418A AU2014243418B2 (en) | 2010-04-30 | 2014-10-09 | Modified binding proteins inhibiting the VEGF-A receptor interaction |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AU2011247563A Division AU2011247563B2 (en) | 2010-04-30 | 2011-04-29 | Modified binding proteins inhibiting the VEGF-A receptor interaction |
Publications (2)
Publication Number | Publication Date |
---|---|
AU2014243418A1 AU2014243418A1 (en) | 2014-10-30 |
AU2014243418B2 true AU2014243418B2 (en) | 2016-09-22 |
Family
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Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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AU2014243418A Active AU2014243418B2 (en) | 2010-04-30 | 2014-10-09 | Modified binding proteins inhibiting the VEGF-A receptor interaction |
Country Status (1)
Country | Link |
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AU (1) | AU2014243418B2 (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010060748A1 (en) * | 2008-11-03 | 2010-06-03 | Molecular Partners Ag | Binding proteins inhibiting the vegf-a receptor interaction |
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2014
- 2014-10-09 AU AU2014243418A patent/AU2014243418B2/en active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2010060748A1 (en) * | 2008-11-03 | 2010-06-03 | Molecular Partners Ag | Binding proteins inhibiting the vegf-a receptor interaction |
Also Published As
Publication number | Publication date |
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AU2014243418A1 (en) | 2014-10-30 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FGA | Letters patent sealed or granted (standard patent) |