AU2014243418B2 - Modified binding proteins inhibiting the VEGF-A receptor interaction - Google Patents

Modified binding proteins inhibiting the VEGF-A receptor interaction

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Publication number
AU2014243418B2
AU2014243418B2 AU2014243418A AU2014243418A AU2014243418B2 AU 2014243418 B2 AU2014243418 B2 AU 2014243418B2 AU 2014243418 A AU2014243418 A AU 2014243418A AU 2014243418 A AU2014243418 A AU 2014243418A AU 2014243418 B2 AU2014243418 B2 AU 2014243418B2
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Australia
Prior art keywords
binding proteins
vegf
binding
receptor interaction
proteins
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AU2014243418A
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AU2014243418A1 (en
Inventor
Hans Kaspar Binz
Patrik Forrer
Michael Tobias Stumpp
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Molecular Partners AG
Original Assignee
Molecular Partners AG
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Publication date
Priority claimed from AU2011247563A external-priority patent/AU2011247563B2/en
Application filed by Molecular Partners AG filed Critical Molecular Partners AG
Priority to AU2014243418A priority Critical patent/AU2014243418B2/en
Publication of AU2014243418A1 publication Critical patent/AU2014243418A1/en
Application granted granted Critical
Publication of AU2014243418B2 publication Critical patent/AU2014243418B2/en
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Abstract

MODIFIED BINDING PROTEINS INHIBITING THE VEGF-A RECEPTOR INTERACTION The present invention relates to binding proteins specific for VEGF-A, in particular to recombinant binding proteins comprising a polyethylene glycol moiety and a binding domain, which inhibits VEGF-Axxx binding to VEGFR-2. Examples of such recombinant binding proteins are proteins which comprise an ankyrin repeat domain with the desired binding specificity, and a polyethylene glycol moiety. The binding proteins are useful in the treatment of cancer and other pathological conditions, e.g. eye diseases such as age-related macular degeneration.
AU2014243418A 2010-04-30 2014-10-09 Modified binding proteins inhibiting the VEGF-A receptor interaction Active AU2014243418B2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2014243418A AU2014243418B2 (en) 2010-04-30 2014-10-09 Modified binding proteins inhibiting the VEGF-A receptor interaction

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP10161685.2 2010-04-30
AU2011247563A AU2011247563B2 (en) 2010-04-30 2011-04-29 Modified binding proteins inhibiting the VEGF-A receptor interaction
AU2014243418A AU2014243418B2 (en) 2010-04-30 2014-10-09 Modified binding proteins inhibiting the VEGF-A receptor interaction

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
AU2011247563A Division AU2011247563B2 (en) 2010-04-30 2011-04-29 Modified binding proteins inhibiting the VEGF-A receptor interaction

Publications (2)

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AU2014243418A1 AU2014243418A1 (en) 2014-10-30
AU2014243418B2 true AU2014243418B2 (en) 2016-09-22

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AU2014243418A Active AU2014243418B2 (en) 2010-04-30 2014-10-09 Modified binding proteins inhibiting the VEGF-A receptor interaction

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AU (1) AU2014243418B2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010060748A1 (en) * 2008-11-03 2010-06-03 Molecular Partners Ag Binding proteins inhibiting the vegf-a receptor interaction

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010060748A1 (en) * 2008-11-03 2010-06-03 Molecular Partners Ag Binding proteins inhibiting the vegf-a receptor interaction

Also Published As

Publication number Publication date
AU2014243418A1 (en) 2014-10-30

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