AU2011375432B2 - Formulations of deoxycholic acid and salts thereof - Google Patents

Formulations of deoxycholic acid and salts thereof Download PDF

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Publication number
AU2011375432B2
AU2011375432B2 AU2011375432A AU2011375432A AU2011375432B2 AU 2011375432 B2 AU2011375432 B2 AU 2011375432B2 AU 2011375432 A AU2011375432 A AU 2011375432A AU 2011375432 A AU2011375432 A AU 2011375432A AU 2011375432 B2 AU2011375432 B2 AU 2011375432B2
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AU
Australia
Prior art keywords
composition
salt
deoxycholic acid
sodium
benzyl alcohol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
AU2011375432A
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English (en)
Other versions
AU2011375432A1 (en
Inventor
Robert Emil Hodge
Robert M. Moriarty
Jeffrey Douglas Webster
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kythera Biopharmaceuticals LLC
Original Assignee
Kythera Biopharmaceuticals LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
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Application filed by Kythera Biopharmaceuticals LLC filed Critical Kythera Biopharmaceuticals LLC
Publication of AU2011375432A1 publication Critical patent/AU2011375432A1/en
Application granted granted Critical
Publication of AU2011375432B2 publication Critical patent/AU2011375432B2/en
Priority to AU2016202661A priority Critical patent/AU2016202661B2/en
Priority to AU2018202807A priority patent/AU2018202807B2/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/08—Solutions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
AU2011375432A 2011-08-23 2011-08-23 Formulations of deoxycholic acid and salts thereof Active AU2011375432B2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2016202661A AU2016202661B2 (en) 2011-08-23 2016-04-27 Formulations of deoxycholic acid and salts thereof
AU2018202807A AU2018202807B2 (en) 2011-08-23 2018-04-23 Formulations of deoxycholic acid and salts thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2011/048806 WO2013028177A1 (en) 2011-08-23 2011-08-23 Formulations of deoxycholic acid and salts thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU2016202661A Division AU2016202661B2 (en) 2011-08-23 2016-04-27 Formulations of deoxycholic acid and salts thereof

Publications (2)

Publication Number Publication Date
AU2011375432A1 AU2011375432A1 (en) 2014-02-06
AU2011375432B2 true AU2011375432B2 (en) 2016-02-04

Family

ID=45569726

Family Applications (3)

Application Number Title Priority Date Filing Date
AU2011375432A Active AU2011375432B2 (en) 2011-08-23 2011-08-23 Formulations of deoxycholic acid and salts thereof
AU2016202661A Active AU2016202661B2 (en) 2011-08-23 2016-04-27 Formulations of deoxycholic acid and salts thereof
AU2018202807A Active AU2018202807B2 (en) 2011-08-23 2018-04-23 Formulations of deoxycholic acid and salts thereof

Family Applications After (2)

Application Number Title Priority Date Filing Date
AU2016202661A Active AU2016202661B2 (en) 2011-08-23 2016-04-27 Formulations of deoxycholic acid and salts thereof
AU2018202807A Active AU2018202807B2 (en) 2011-08-23 2018-04-23 Formulations of deoxycholic acid and salts thereof

Country Status (18)

Country Link
JP (1) JP5919597B2 (es)
KR (5) KR20200013103A (es)
CN (3) CN108619089A (es)
AU (3) AU2011375432B2 (es)
BR (1) BR112014000547B1 (es)
CA (1) CA2842177C (es)
CR (1) CR20140053A (es)
EA (1) EA029305B1 (es)
IL (1) IL230547A (es)
IN (1) IN2014CN02188A (es)
MX (1) MX350390B (es)
MY (1) MY184277A (es)
NZ (1) NZ620040A (es)
PH (1) PH12016501175A1 (es)
SG (1) SG2014013205A (es)
UA (1) UA113522C2 (es)
WO (1) WO2013028177A1 (es)
ZA (1) ZA201401027B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8101593B2 (en) 2009-03-03 2012-01-24 Kythera Biopharmaceuticals, Inc. Formulations of deoxycholic acid and salts thereof
MX2018005628A (es) * 2015-11-04 2018-08-01 Kythera Biopharmaceuticals Inc Tratamientos de grasa acumulada con acido desoxicolico y sales del mismo.
US20180078621A1 (en) * 2016-09-22 2018-03-22 Kyoung Lack Lee Composition for hypotonic lipolysis and manufacturing method thereof
KR101841193B1 (ko) * 2016-09-22 2018-03-22 이경락 저장성 지방 분해 조성물 및 그의 제조 방법
JP7042531B2 (ja) * 2018-04-16 2022-03-28 ペンミックス リミテッド デオキシコール酸を含む医薬組成物
KR102172439B1 (ko) 2018-12-05 2020-10-30 송미희 지방 분해용 조성물 및 이를 포함하는 주사제 조성물
KR102064864B1 (ko) 2019-02-08 2020-01-10 (주)제테마 국소 주사용 조성물
KR102111346B1 (ko) * 2019-08-20 2020-05-22 아영창 침전으로부터 안정한 소듐디옥시콜레이트를 포함하는 수용액상 조성물
KR20220026068A (ko) 2020-08-25 2022-03-04 강명범 지방 분해용 주사제 조성물
CN116617160A (zh) * 2023-07-25 2023-08-22 山东则正医药技术有限公司 水性混悬液及制备方法、冻干粉及应用、脂肪消减注射剂

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417179B1 (en) * 1998-10-13 2002-07-09 Craig G. Burkhart Ear wax solution

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2754709B1 (fr) 1996-10-23 1999-03-05 Sanofi Sa Composition cosmetique contenant un antagoniste des recepteurs du neuropeptide gamma et alpha 2 antagonistes susceptibles d'etre incorpores dans une telle composition
RU2224523C2 (ru) * 1998-07-24 2004-02-27 Сео Хонг Ю Водный раствор, содержащий желчную кислоту, и способ его получения
US20050048126A1 (en) * 2000-12-22 2005-03-03 Barrett Rabinow Formulation to render an antimicrobial drug potent against organisms normally considered to be resistant to the drug
DE10361067A1 (de) * 2003-12-22 2005-07-14 Aventis Pharma Deutschland Gmbh Medikamentöse Lipolyse von Fettansammlungen
US20060127468A1 (en) 2004-05-19 2006-06-15 Kolodney Michael S Methods and related compositions for reduction of fat and skin tightening
US7754230B2 (en) 2004-05-19 2010-07-13 The Regents Of The University Of California Methods and related compositions for reduction of fat
ES2372499T3 (es) * 2004-05-19 2012-01-20 Los Angeles Biomedical Research Institute At Harbor-Ucla Medical Center Uso de un detergente para la eliminación no quirúrgica de grasa.
CA2610022A1 (en) 2005-06-06 2006-12-14 Georgetown University Compositions and methods for lipo modeling
TW201011755A (en) 2008-09-10 2010-03-16 Skymedi Corp Flash memory system and its data recovery method
JP5420946B2 (ja) * 2009-03-23 2014-02-19 富士フイルム株式会社 胆汁酸を含むミノキシジル水性組成物
EP2645099A1 (en) * 2012-03-30 2013-10-02 Phares Pharmaceutical Research N.V. Biorelevant compositions

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6417179B1 (en) * 1998-10-13 2002-07-09 Craig G. Burkhart Ear wax solution

Also Published As

Publication number Publication date
UA113522C2 (xx) 2017-02-10
MX2014001495A (es) 2014-04-25
AU2016202661B2 (en) 2018-02-22
PH12016501175B1 (en) 2017-12-11
AU2016202661A1 (en) 2016-05-19
BR112014000547B1 (pt) 2021-11-09
IN2014CN02188A (es) 2015-05-29
MY184277A (en) 2021-03-30
WO2013028177A1 (en) 2013-02-28
KR102073536B1 (ko) 2020-02-04
KR20170075016A (ko) 2017-06-30
KR101751585B1 (ko) 2017-06-27
PH12016501175A1 (en) 2017-12-11
KR20190119677A (ko) 2019-10-22
CA2842177C (en) 2016-07-19
CN108743522A (zh) 2018-11-06
BR112014000547A2 (pt) 2017-02-14
ZA201401027B (en) 2017-09-27
MX350390B (es) 2017-09-06
CN108619089A (zh) 2018-10-09
EA029305B1 (ru) 2018-03-30
IL230547A0 (en) 2014-03-31
EA201490175A1 (ru) 2014-06-30
CN103826608A (zh) 2014-05-28
NZ620040A (en) 2016-06-24
JP5919597B2 (ja) 2016-05-18
KR20150000448A (ko) 2015-01-02
CA2842177A1 (en) 2013-02-28
JP2014524467A (ja) 2014-09-22
AU2018202807B2 (en) 2020-01-16
AU2018202807A1 (en) 2018-05-10
KR20200013103A (ko) 2020-02-05
AU2011375432A1 (en) 2014-02-06
KR20180123734A (ko) 2018-11-19
SG2014013205A (en) 2014-05-29
KR102034606B1 (ko) 2019-10-22
KR101919269B1 (ko) 2018-11-15
CR20140053A (es) 2014-06-12
IL230547A (en) 2017-02-28

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