AU2009100021A4 - Prevention of formation of biocidal resistant strains of microorganisms - Google Patents
Prevention of formation of biocidal resistant strains of microorganisms Download PDFInfo
- Publication number
- AU2009100021A4 AU2009100021A4 AU2009100021A AU2009100021A AU2009100021A4 AU 2009100021 A4 AU2009100021 A4 AU 2009100021A4 AU 2009100021 A AU2009100021 A AU 2009100021A AU 2009100021 A AU2009100021 A AU 2009100021A AU 2009100021 A4 AU2009100021 A4 AU 2009100021A4
- Authority
- AU
- Australia
- Prior art keywords
- biocide
- health care
- washing
- hand washing
- hands
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
- A01N31/16—Oxygen or sulfur directly attached to an aromatic ring system with two or more oxygen or sulfur atoms directly attached to the same aromatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N31/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic oxygen or sulfur compounds
- A01N31/08—Oxygen or sulfur directly attached to an aromatic ring system
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N47/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid
- A01N47/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides
- A01N47/42—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom not being member of a ring and having no bond to a carbon or hydrogen atom, e.g. derivatives of carbonic acid the carbon atom having a double or triple bond to nitrogen, e.g. cyanates, cyanamides containing —N=CX2 groups, e.g. isothiourea
- A01N47/44—Guanidine; Derivatives thereof
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N59/00—Biocides, pest repellants or attractants, or plant growth regulators containing elements or inorganic compounds
- A01N59/12—Iodine, e.g. iodophors; Compounds thereof
Description
Regulation 3.2 Revised 2/98
AUSTRALIA
Patents Act, 1990 COMPLETE INNOVATION SPECIFICATION NAME OF APPLICANT ACTUAL INVENTOR ADDRESS FOR SERVICE INVENTION TITLE: DETAILS OF ASSOCIATED PROVISIONAL APPLICATION NO(S): Bruno Anthony Glueck GLUECK, Bruno Anthony Peter Maxwell and Associates Level 6 Pitt Street SYDNEY NSW 2000 PREVENTION OF FORMATION OF BIOCIDAL RESISTANT STRAINS OF
MICROORGANISMS
2008 906 235 2 December 2008 AU The following statement is a full description of this invention including the best method of performing it known to me:m:\docs\20091005\159149.doc PREVENTION OF FORMATION OF BIOCIDAL RESISTANT STRAINS OF MICROORGANISMS TECHNICAL FIELD The present invention relates to a process for preventing the formation in a health care environment of antimicrobial resistant microorganisms. The present invention also relates to a process for the gradual elimination from such an environment of antimicrobial resistant microorganisms.
BACKGROUND
ART
It is well known that infections with pathogenic microorganisms are spread to patients by skin contact with health care personnel, say, working in a hospital.
Commonly, the only recommendation to prevent the spread of infection within a hospital is for a health care professional to frequently wash his or her hands with an antiseptic hand washing product containing a biocide. The use and frequency of hand washing routines have become an integral part of infection control. It is ideally after each patient contact that the hands of health care personnel should be washed with an antiseptic hand washing product containing a biocide.
The formation of antimicrobial resistant strains of microorganisms, however, can be caused by prolonged contact and over exposure to the same biocide through the natural selection of those microorganisms that survive the biocide. Hospitals normally make the same biocide available to all their health care personnel so that, after each patient contact, the hands are washed with the same biocide.
13/01/09 Even with the strictest adherence to hand washing routines by health care personnel in a hospital, there are reports of the growing concern at the increase of antimicrobial resistant microorganisms and, more specifically, antibiotic resistant strains of microorganisms infecting patients by skin contact with health care personnel.
There are many published reports and guidelines for hand washing procedures for health care personnel working in a hospital. A report at the 1 0 5 th General Meeting of the American Society for Microbiology in June 2005 states: "that methiciline resistant staphylococcus aureus (MRSA) studies demonstrated the need for frequent hand washing in health care settings due to the potential of MRSA being transferred from person to person".
The hand washing instructions issued in August 2008 by the Department of Microbiology and Immunology in the Faculty of Medicine of Melbourne University in accordance with Australian standard procedure AS/NZS 4815 provide strict rules for the procedure of how the hands are to be washed.
However, none of these reports and guidelines for hand washing procedures for health care personnel recommend a hand washing routine in which health care personnel use a different hand washing product containing a different biocide at each hand wash.
DESCRIPTION OF THE INVENTION It is an object of the present invention to overcome, or at least substantially ameliorate, the disadvantages and shortcomings of the aforementioned prior art.
It is another object of the present invention to provide a process for the prevention of infections due to the transfer of transient antimicrobial resistant 13/01/09 microorganisms from the hands of health care personnel to patients in a health care environment.
Accordingly, the present invention provides a process for preventing the formation in a health care environment of antimicrobial resistant pathogenic microorganisms, comprising:providing a first antiseptic hand washing product containing a first biocide, (ii) providing a second antiseptic hand washing product containing a second biocide different to the first biocide, (iii) washing the hands of a health care professional infected, or at risk of being infected, with one or more pathogenic microorganism after skin contact with a patient, the washing being with the first product, and (iv) washing the hands of the health care professional after further skin contact with a patient with the second product so as to effectively eliminate any pathogenic microorganism infecting the hands of the health care professional after the washing with the previous product.
Preferably, the process further provides a third or more additional antiseptic hand washing product containing a respective third or further biocide, and repeating step (iv) with the, or each of the, third or more additional antiseptic hand washing product.
It is preferred that the biocides contained in the antiseptic hand washing products are selected from the group consisting of: an alcohol, 5-chloro-2-(2,4-dichlorophenoxy)phenol (Triclosan), Chlorhexidine, quaternary ammonium compounds, octenidine dihydrochloride, parachlorometaxylenol (PCMX), and iodophors.
13/01/09 In a preferred form, the first and second biocides are Chlorhexidine and Triclosan, respectively.
In another preferred form, the first, second and third biocides are an alcohol, Triclosan and Chlorhexidine, respectively.
Frequent hand washing with antiseptic products each containing different biocides prevents the formation of antimicrobial resistant microorganisms and, more specifically, antibiotic resistant strains of microorganisms, as the bacterial, fungal and viral hand flora would not be continuously exposed to the same biocide.
Furthermore, washing the hands after each skin contact with a patient with a different antiseptic hand washing product containing a different biocide avoids irritation and dermatitis of the skin, as the skin is not being continuously confronted with the same biocides and washing agents also contained in the antiseptic hand washing products.
The term "comprising" as used herein is intended to be interpreted in an inclusive sense, akin to the terms "including" and "containing". The term "comprising" is not intended to be interpreted in an exclusive sense, akin to the terms "consisting of' or "composed of'.
BEST METHOD FOR CARRYING OUT THE INVENTION The washing of the hands of health care professionals using antiseptic hand washing products containing different biocides can be facilitated by placing dispenser apparatus, such as dispenser bottles, filled with each of the different antiseptic hand washing products at a suitable distance from each other in a wash room or other dedicated facility in a health care environment.
13/01/09 Each dispenser apparatus will constitute a separate washing station at which a health care professional must wash his or her hands after skin contact with a patient.
The antiseptic hand washing products can be selected from, but are not restricted to, those which contain as biocides: an alcohol, Chlorhexidine, 5-chloro-2-(2,4-dichlorophenoxy)phenol (Triclosan), quaternary ammonium compounds, parachlorometaxylenol (PCMX), octenide dihydrochloride and an iodophor.
The following examples illustrate some preferred sequences of antiseptic hand washing products each containing different biocides that can be used as hand washing routines, and which are suitable for the prevention of formation of antimicrobial resistant pathogenic microorganisms. They should not be construed as limiting.
Biocide Sequence 1 Wash 1, use Chlorhexidine, Wash 2, use Triclosan.
Biocide Sequence 2 Wash 1, use an Alcohol, Wash 2, use Triclosan, Wash 3, use Chlorhexidine.
Biocide Sequence 3 Wash 1, use an Alcohol, Wash 2, use Quaternary ammonium compound, Wash 3, use PCMX, Wash 4, use Octenidine dihydrochloride, Wash 5, use Triclosan.
13/01/09 Biocide Seauence 4 Wash 1, use lodophor, Wash 2, use Triclosan, Wash 3, use Chlorhexidine, Wash 4, use PCMX.
It will be apparent to persons skilled in the art that a large number of combinations and permutations of biocide sequences may be suitable for use in washing routines of the present invention. These may include many proven, commercially available, antiseptic hand washing products, as well as biocide containing products not yet in use.
It will also be apparent to persons skilled in the art that various modifications may be made in details of process steps and composition of biocides used in the process without departing from the scope or ambit of the present invention.
13/01/09
Claims (4)
1. A process for preventing the formation in a health care environment of antimicrobial resistant pathogenic microorganisms, comprising:- providing a first antiseptic hand washing product containing a first biocide, (ii) providing a second antiseptic hand washing product containing a second biocide different to the first biocide, (iii) washing the hands of a health care professional infected, or at risk of being infected, with one or more pathogenic microorganism after skin contact with a patient, the washing being with the first product, and (iv) washing the hands of the health care professional after further skin contact with a patient with the second product so as to effectively eliminate any pathogenic microorganism infecting the hands of the health care professional after the washing with the previous product.
2. The process of claim 1 further providing a third or more additional antiseptic hand washing product containing a respective third or further biocide, and repeating step (iv) with the, or each of the, third or more additional antiseptic hand washing product.
3. The process of claim 1 or claim 2 wherein the biocides contained in the antiseptic hand washing products are selected from the group consisting of: an alcohol, 5 -chloro-2-(2,4-dichlorophenoxy)phenol (Triclosan), Chlorhexidine, 13/01/09 quaternary ammonium compounds, octenidine dihydrochloride, parachlorometaxylenol (PCMX), and iodophors.
4. The process of any one of claims 1 to 3 wherein the first and second biocides are Chlorhexidine and Triclosan, respectively. The process of any one of claims 1 to 3 wherein the first, second and third biocides are an alcohol, Triclosan and Chlorhexidine, respectively. Dated this 13 day of January 2008 Bruno Anthony Glueck Patent Attorneys for the Applicant PETER MAXWELL AND ASSOCIATES 13/01/09
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2009100021A AU2009100021A4 (en) | 2008-12-02 | 2009-01-15 | Prevention of formation of biocidal resistant strains of microorganisms |
| PCT/GB2009/051633 WO2010064039A1 (en) | 2008-12-02 | 2009-12-02 | Prevention of formation of biocidal resistant strains of microorganisms |
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU2008906235 | 2008-12-02 | ||
| AU2008906235A AU2008906235A0 (en) | 2008-12-02 | Procedure to minimise the formation of biolidal resistant strains of micro-organism | |
| AU2009100021A AU2009100021A4 (en) | 2008-12-02 | 2009-01-15 | Prevention of formation of biocidal resistant strains of microorganisms |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| AU2009100021A4 true AU2009100021A4 (en) | 2009-02-19 |
Family
ID=40385116
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AU2009100021A Ceased AU2009100021A4 (en) | 2008-12-02 | 2009-01-15 | Prevention of formation of biocidal resistant strains of microorganisms |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU2009100021A4 (en) |
| WO (1) | WO2010064039A1 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104207970A (en) * | 2014-03-21 | 2014-12-17 | 郭健 | Medical skin-care disinfection hand-cleaning liquid and preparation method thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2424003A1 (en) * | 2003-03-28 | 2004-09-28 | Austin & Repatriation Medical Centre | Anti-microbial topical composition comprising alcohol and chlorhexidine salt |
| DE102005002645A1 (en) * | 2005-01-19 | 2006-07-20 | Schülke & Mayr GmbH | Alcoholic compositions for disinfection |
-
2009
- 2009-01-15 AU AU2009100021A patent/AU2009100021A4/en not_active Ceased
- 2009-12-02 WO PCT/GB2009/051633 patent/WO2010064039A1/en active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO2010064039A1 (en) | 2010-06-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FGI | Letters patent sealed or granted (innovation patent) | ||
| MK22 | Patent ceased section 143a(d), or expired - non payment of renewal fee or expiry |