AU2003300522A1 - 4-phenyl-pyrimido (4,5-b) indole derivatives - Google Patents

4-phenyl-pyrimido (4,5-b) indole derivatives

Info

Publication number
AU2003300522A1
AU2003300522A1 AU2003300522A AU2003300522A AU2003300522A1 AU 2003300522 A1 AU2003300522 A1 AU 2003300522A1 AU 2003300522 A AU2003300522 A AU 2003300522A AU 2003300522 A AU2003300522 A AU 2003300522A AU 2003300522 A1 AU2003300522 A1 AU 2003300522A1
Authority
AU
Australia
Prior art keywords
pyrimido
phenyl
indole derivatives
indole
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU2003300522A
Inventor
Kevin B. Bacon
Florian Gantner
Tadashi Inoue
Hiroshi Komura
Tai-Wei Ly
Aiko Muramatsu
Hiromi Okigami
Hiroki Sato
Makoto Shimazaki
Naoki Tsuno
Klaus Urbahns
Nagahiro Yoshida
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer Healthcare AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Healthcare AG filed Critical Bayer Healthcare AG
Publication of AU2003300522A1 publication Critical patent/AU2003300522A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
AU2003300522A 2002-12-27 2003-12-13 4-phenyl-pyrimido (4,5-b) indole derivatives Abandoned AU2003300522A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP02029029.2 2002-12-27
EP02029029 2002-12-27
PCT/EP2003/014194 WO2004058764A1 (en) 2002-12-27 2003-12-13 4-phenyl-pyrimido [4,5-b] indole derivatives

Publications (1)

Publication Number Publication Date
AU2003300522A1 true AU2003300522A1 (en) 2004-07-22

Family

ID=32668748

Family Applications (1)

Application Number Title Priority Date Filing Date
AU2003300522A Abandoned AU2003300522A1 (en) 2002-12-27 2003-12-13 4-phenyl-pyrimido (4,5-b) indole derivatives

Country Status (2)

Country Link
AU (1) AU2003300522A1 (en)
WO (1) WO2004058764A1 (en)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2247558T (en) 2008-02-14 2022-03-21 Lilly Co Eli Novel imaging agents for detecting neurological dysfunction
EP2161271A1 (en) * 2008-09-08 2010-03-10 Università Degli Studi Di Milano - Bicocca Alpha-carboline inhibitors of NMP-ALK, RET, and Bcr-Abl
MX2011004306A (en) 2008-10-22 2011-07-28 Genentech Inc Modulation of axon degeneration.
KR20120102642A (en) 2009-10-22 2012-09-18 제넨테크, 인크. Modulation of axon degeneration
US9732083B2 (en) * 2011-03-15 2017-08-15 Merck Sharp & Dohme Corp. Tricyclic gyrase inhibitors
RS59002B1 (en) * 2012-01-27 2019-08-30 Univ Montreal Pyrimido[4,5-b]indole derivatives and use thereof in the expansion of hematopoietic stem cells
AU2014225889B2 (en) * 2013-03-06 2018-12-06 The Johns Hopkins University CaMKII inhibitors and uses thereof
CA2848575C (en) * 2013-05-17 2021-01-26 Universite De Montreal Methods to modulate acute myeloid leukemia stem/progenitor cell expansion and/or differentiation
US20170029778A1 (en) 2013-06-11 2017-02-02 President And Fellows Of Harvard College Sc-beta cells and compositions and methods for generating the same
CA2960101A1 (en) 2014-09-05 2016-03-10 Allosteros Therapeutics, Inc. Substituted carboline derivative and compositions thereof useful as camkii inhibitors
PL3194602T3 (en) * 2014-09-18 2020-07-27 Université de Montréal Compounds and methods for enhancing viral gene transfer to human hematopoietic cells
WO2016100930A1 (en) 2014-12-18 2016-06-23 President And Fellows Of Harvard College Methods for generating stem cell-derived b cells and methods of use thereof
WO2016100909A1 (en) 2014-12-18 2016-06-23 President And Fellows Of Harvard College METHODS FOR GENERATING STEM CELL-DERIVED β CELLS AND USES THEREOF
US10443042B2 (en) 2014-12-18 2019-10-15 President And Fellows Of Harvard College Serum-free in vitro directed differentiation protocol for generating stem cell-derived beta cells and uses thereof
AU2016273439B2 (en) 2015-06-05 2020-11-05 Héma-Québec Methods for culturing and/or differentiating hematopoietic stem cells into progenitors and uses thereof
BR112020009275A2 (en) 2017-11-15 2020-10-27 Semma Therapeutics, Inc. islet cell manufacturing compositions and methods of use
KR20200138166A (en) 2018-01-31 2020-12-09 헤파레게닉스 게엠베하 Protein kinase MKK4 inhibitors to promote liver regeneration or to reduce or prevent hepatocyte death
US11731968B2 (en) 2018-06-21 2023-08-22 Heparegenix Gmbh Tricyclic protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death
JP7365393B2 (en) 2018-07-16 2023-10-19 ヘパリジェニックス ゲーエムベーハー Protein kinase inhibitors for promoting liver regeneration or suppressing or preventing hepatocyte death
AU2019320072A1 (en) 2018-08-10 2021-02-25 Vertex Pharmaceuticals Incorporated Stem cell derived islet differentiation
WO2020225077A1 (en) * 2019-05-03 2020-11-12 Idorsia Pharmaceuticals Ltd Pyrimido[4,5-b]indol derivatives as pdhk1 inhibitors
WO2021018820A1 (en) * 2019-07-29 2021-02-04 Heparegenix Gmbh Heteroaryl-substituted pyrazolo-pyridine protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death
KR20220114569A (en) * 2019-12-18 2022-08-17 유니버시떼 드 몬트리얼 Modulator of CULLIN 3 adapter KBTBD4 as anticancer compound

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL334451A1 (en) * 1997-01-08 2000-02-28 Upjohn Co Pharmaceutically active tricyclic amines
EP1442039A1 (en) * 2001-10-31 2004-08-04 Bayer HealthCare AG Pyrimido (4,5-b) indole derivatives

Also Published As

Publication number Publication date
WO2004058764A1 (en) 2004-07-15

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase